抗体

抗SLC38A1抗体

蚂蚁-184

1 X 50 mcl

530美元

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化

蚂蚁-184

Primary Antibody>Intracellular>Non-Labeled

Insert

抗SLC38A1抗体

Anti-SLC38A1 Antibody (#ANT-184) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize SNAT1 from human, rat, and mouse samples.

A兔多克隆抗体SLC38A1转运蛋白

BLP-NT184

Sodium-coupled neutral amino acid transporter 1, Snat1, Amino acid transporter A1, rATA1, Glutamine transporter, N-system amino acid transporter 2, Ata1, Glnt, Sa2, Sat1

SLC38A1转运蛋白

Transporters , Exchangers and Pumps > Amino Acid Transporters > SLC38 Family > Antibodies

未共轭

免疫组化, 免疫印迹

兔

多克隆

兔IgG

SLC38A1

人类(试验);小鼠(试验);大鼠(试验)

Mouse, human – identical.

Lynx1 is a member of the Ly-6/neurotoxin gene superfamily (Lynx family) of proteins that feature a three-looped toxin fold and a cysteine rich motif; structural characteristics that are shared with the snake venom toxin α-bungarotoxin1. Lynx1 is expressed in large projection neurons in the hippocampus, cortex, and cerebellum. Initial analysis of the functional consequence of genetic ablation of Lynx1 in mice revealed that Lynx1 is an allosteric modulator of various nicotinic receptors that affects their kinetics, decreases their agonist affinities, and increases their desensitization to overall limit their activation. Lynx1 can serve as a protective measure against neurotoxicity through agonist-induced overstimulation2. In fact, deletion of Lynx1 eventually leads to neurodegeneration in aged mice3. Collectively the findings regarding Lynx1 suggest a direct relationship between plasticity regulation and nicotinic signaling, and underline the significance of fine tuning of nicotinic tone to vastly control the development of brain functions.Lynx1 activity was shown to be related to the pathophysiology of Alzheimer’s disease as well as cholinergic activity in healthy and tumor cells of bronchial epithelium4.

合成肽

intracellular

Cytoplasmic, N-terminus

(C)SKFISDRESRRSLTNSH, corresponding to amino acid residues 41-57 of rat SLC38A1

Peptide (C)SKFISDRESRRSLTNSH, corresponding to amino acid residues 41-57 of rat SLC38A1 (Accession Q9JM15). Cytoplasmic, N-terminus.

1 X 50 mcl

0.8毫克/毫升

08毫克/毫升

磷酸盐缓冲液(PBS)

pH值7.4

1% BSA, 0.05% NaN3 (% of reconstituted antibody)

Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

冻干粉末

Affinity purified on immobilized antigen

-20°C

Q9JM15

AHC-001

Reconstitution: 1 X 50 mcl double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C, as long as it is in its original form, it can last a minimum of 3 years this way. The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

1

50

mcl

530美元