产品简要
公司名称 :
Alomone Labs
产品类型 :
抗体
产品名称 :
Anti-Cortactin Antibody
目录 :
APZ-018
规格 :
1 X 0.2毫升
价格 :
637美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
图像
图像 1 :
Alomone Labs APZ-018 图像 1
Western blot analysis of rat brain lysate (lanes 1 and 3) and mouse brain lysate (lanes 2 and 4): - 1, 2. Anti-Cortactin Antibody (#APZ-018), (1:1000). 3, 4. Anti-Cortactin Antibody, preincubated with Cortactin Blocking Peptide (#BLP-PZ018).
产品信息
SKU号 :
APZ-018_1_0.2_ml
ParentSKU :
APZ-018
Taxonomy Node :
Primary Antibody>Intracellular>Non-Labeled
Action :
Insert
产品名称 :
Anti-Cortactin Antibody
产品描述 :
Anti-Cortactin Antibody (#APZ-018) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot analysis. It has been designed to recognize Cortactin from rat, mouse, and human samples.
Short Description :
A Rabbit Polyclonal Antibody to Cortactin
Negative Control :
BLP-PZ018
同义词 :
Src substrate cortactin, Oncogene EMS1, EMS1, Amplaxin, CTTN
靶标名 :
Cortactin
Primary Category (Old) :
Neural Signaling > Scaffolding proteins > Antibodies
标记/共轭标签 :
未共轭
应用 :
免疫组化, 免疫印迹
宿主 :
克隆性 :
多克隆
抗体亚型 :
兔IgG
基因符号 :
Cttn
反应物种 :
人类(试验);小鼠(试验);大鼠(试验)
同源 :
Rat, human – identical.
靶标/背景信息 :
Otopetrin-1 (Otop-1) is a proton channel involved in sour taste recognition. It belongs to the Otopetrin proton channel family together with Otopetrins-2 and 31. Otop-1 is a dimeric structure, with each subunit forming 12 transmembrane helices divided into structurally similar N- and C-domains2. Taste recognition is very important because it enables to sample chemicals in the environment prior to digestion and hence, plays an important role in feeding and avoiding intoxication2. The sense of sour taste is caused by acids, and the first step in sour taste transduction is an influx of H+ ions through Otop-1 channel into the type three Taste Receptor Cells (TRCs). This leads to a decrease in intracellular pH and operation of a signaling cascade1-3. Otop-1 is specifically expressed in type three taste cells and exhibits the Zn2+ sensitivity that is a key feature observed in the proton current of sour taste cells4. Otop-1 also has a role in regulating intracellular Ca2+ levels required for the formation of otoconia in the vertebrate inner ear. Otoconia are complex calcium carbonate biominerals required for the sensation of gravity5.
免疫原 :
合成肽
区域 :
intracellular
Loop :
Intracellular
序列 :
(C)KTSNIRANFENLAK, corresponding to amino acid residues 346 - 359 of mouse Cortactin
序列文本 :
Peptide (C)KTSNIRANFENLAK, corresponding to amino acid residues 346 - 359 of mouse Cortactin (Accession Q60598). Intracellular.
Primary Size (Size+Units) :
1 X 0.2毫升
浓度 :
0.8毫克/毫升
浓度 :
08毫克/毫升
缓冲液 :
磷酸盐缓冲液(PBS)
pH值 :
pH值7.4
防腐剂 :
1% BSA, 0.05% NaN3 (% of reconstituted antibody)
Additive(s) :
Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
格式(液体/冻干) :
冻干粉末
纯化来源(杂交瘤细胞, 腹水 :
Affinity purified on immobilized antigen
储存温度 :
-20°C
UniProt数据库 :
Q14247
储存和重组 :
Reconstitution: 1 X 0.2 ml double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C, as long as it is in its original form, it can last a minimum of 3 years this way. The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
包装规格 :
1
产品规格/规格 :
0.2
单位 :
毫升
标价美国[美元] :
637美元
更多信息或购买 :
公司信息
Alomone Labs
Jerusalem BioPark (JBP), Hadassah Ein Kerem
P.O. Box 4287
Jerusalem 9104201
info@alomone.com
http://www.alomone.com
972-2-587-2202
公司总部: 以色列
Alomone Labs公司成立于1989年,在离子通道、GPCR及神经信号通路研究等领域占据全球领先地位。