产品简要
公司名称 :
Alomone Labs
产品类型 :
化学品
产品名称 :
Chelerythrine chloride
目录 :
C-400
规格 :
1毫克
更多信息或购买 :
Alomone Labs 产品网页
文章摘录数: 4
参考文献
Garcia N, Balañà C, Lanuza M, Tomas M, Cilleros Mañé V, Just Borràs L, et al. Opposed Actions of PKA Isozymes (RI and RII) and PKC Isoforms (cPKCβI and nPKCε) in Neuromuscular Developmental Synapse Elimination. Cells. 2019;8: pubmed 出版商
Mohan S, Nath M, Biala Y, Yaari Y. Regulation of neuronal Na+/K+-ATPase by specific protein kinases and protein phosphatases. J Neurosci. 2019;: pubmed 出版商
Libster A, Title B, Yarom Y. Corticotropin-releasing factor increases Purkinje neuron excitability by modulating sodium, potassium, and Ih currents. J Neurophysiol. 2015;114:3339-50 pubmed 出版商
Hoggard J, Fan J, Lu Z, Lu Q, Sutton L, Chen Y. Claudin-7 increases chemosensitivity to cisplatin through the upregulation of caspase pathway in human NCI-H522 lung cancer cells. Cancer Sci. 2013;104:611-8 pubmed 出版商
图像
图像 1 :
Alomone Labs C-400 图像 1
Alomone Labs Chelerythrine chloride inhibits PKC in NIH-3T3 cells. - Cells were incubated with different concentrations ofChelerythrine chloride(#C-400) for 30 min and then stimulated withPMA(#P-800) (3 ng/ml) for 20 min. Cell proteins were resolved by SDS-PAGE and probed with anti-phospho (ser)-MARCKS (myristoylated alanin-rich protein kinase C substrate).
图像 2 :
Alomone Labs C-400 图像 2
Western blot analysis of human neuroblastoma (SH-SY5Y) (lanes 1 and 4) human brain astrocytoma (CCF-STTGI) (lanes 2 and 5) and rat pheochromocytoma (PC12) (lanes 3 and 6): - 1-3.Anti-CRF1/CRHR1 (extracellular) Antibody(#ACR-050) (1:200).4-6. Anti-CRF1/CRHR1 (extracellular) Antibody preincubated with the negative control antigen.
产品信息
产品种类 :
Small Molecule
产品名称 :
Chelerythrine chloride
产品描述 :
Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C (PKC). It is at least 100-fold more selective for PKCs than for other kinases.
Package Content :
Reagent vial, SDS documentation
品牌名 :
Alomone Labs
ManufacturerCatalogID :
C-400
SupplierCatalogID :
C-400
包装规格 :
1
产品规格/规格 :
1毫克
单位 :
毫克
Minimum Order Quantity :
1
船国家[美国] :
以色列
Default Carrier [US] :
Fedex
Order Processing Time [US] :
1
Est. Transit Time [US] :
3
船国家[GB] :
以色列
Default Carrier [GB] :
Fedex
Order Processing Time [GB] :
1
Est. Transit Time [GB] :
3
船国家[EU] :
以色列
Default Carrier [EU] :
Fedex
Order Processing Time [EU] :
1
Est. Transit Time [EU] :
3
美国HS编码 :
2933.99.8290
EU HS编码 :
2933998090
船细节 :
Ship at room temperature, temperature stabilized product
CAS# :
3895-92-9
靶标 :
PKC, SERCA pumps, P2X7 receptor
活性 :
Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C (PKC). It is at least 100-fold more selective for PKCs than for other kinases.
类型 :
Antagonists & Inhibitors
分子名称 :
1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride.
起源 :
Macleaya Cordata.
基因/蛋白号码 :
PRKCA, ATP2A1, ATP2A2, ATP2A3, P2RX7
来源 :
Macleaya Cordata.
配方 :
C21H18ClNO4
分子量 :
383.84
格式 :
Lyophilized/solid.
纯度 :
>99%
主要种类 :
Ion Channels > Cell Signaling Tools > Protein Kinases > Inhibitors
更多信息或购买 :
Alomone Labs 产品网页
公司信息
Alomone Labs
Jerusalem BioPark (JBP), Hadassah Ein Kerem
P.O. Box 4287
Jerusalem 9104201
info@alomone.com
http://www.alomone.com
972-2-587-2202
公司总部: 以色列
Alomone Labs公司成立于1989年，在离子通道、GPCR及神经信号通路研究等领域占据全球领先地位。