This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
Alomone Labs
产品类型 :
化学品
产品名称 :
Roscovitine
目录 :
R-300
规格 :
1毫克, 5 x 1毫克, 5毫克
产品信息
供应商 :
Alomone Labs Ltd.
产品名 :
Roscovitine
目录号 :
R-300
规格 :
1毫克, 5 x 1毫克, 5毫克
类型 :
Antagonists Inhibitors
分子名称 :
2-(R)-1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine.
CAS登记号码 :
186692-46-6
来源/表达系统 :
Synthetic
活性 :
Roscovitine is an olomoucine-related purine flavopiridol. In contrast to Olomoucine, Roscovitine is a highly specific and strong inhibitor for the kinase activity of CDK1, CDK2, CDK5, and CDK7. Roscovitine arrests the cell cycle at G1, prevents proliferation and induces apoptosis in mammalian cells by inhibition of the CDK-STAT pathway.
分子量 :
354.46
基因符号 :
CACNA1G, CACNA1H, CACNA1I
靶标 :
CDKs, T-type Cav channels
配方 :
C19H26N6O
格式 :
Lyophilized/solid.
纯度 :
99%
产品描述 :
A Cyclin-Dependent Kinase (CDK) Inhibitor and a T-Type Cav Channel Blocker
类别 :
Protein Kinases, Cell signaling, Cell Signalling, Ca2+ signaling, Ca2+ signalling, G-protein coupled receptors, G protein-coupled receptors, GPCRs, Ion Channels, Chemicals and Reagents, Inhibitors, Biomolecules, Blockers, Antagonists
研究领域 :
Cardiovascular, Cardiac, Heart, Alzheimer's Disease, Neurodegenerative Disorders, Pain, Nociception, Epilepsy, Neuroscience
公司信息
Alomone Labs
Jerusalem BioPark (JBP), Hadassah Ein Kerem
P.O. Box 4287
Jerusalem 9104201
info@alomone.com
http://www.alomone.com
972-2-587-2202
公司总部: 以色列
Alomone Labs公司成立于1989年，在离子通道、GPCR及神经信号通路研究等领域占据全球领先地位。