蛋白

MAPK1, 1-360aa, 人类, 多聚组氨酸标签, 大肠杆菌, 重组

01-1755-1

10微克

139.00美元

MAPK1, 1-360aa, 人类, 多聚组氨酸标签, 大肠杆菌, 重组

重组蛋白

10微克

139.00美元

MAPK1, also known as ERK(extracellular signal-regulated kinase), acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Recombinant human MAPK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

> 95% by SDS - PAGE

Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.

1毫克/毫升(由布拉德福德Bradford检测确定)

可以储存在+4C短期(1-2周)。 为长期储存, 分成小份儿保存在-20C或-70C。 避免反复冻融

Hu S., et al. (2009) Cell. 139(3):610-22.McGargill MA., et al. (2009) J Immunol. 183(8):4838-42.