产品简要
信息索取 :
公司名称 :
American Research Products
产品类型 :
抗体
产品名称 :
抗Hsp27
目录 :
01-2439
规格 :
200微升
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
人类
更多信息或购买 :
产品信息
目录代码 :
01-2439
产品名称 :
抗Hsp27
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
纯化
产品类型 :
小鼠单克隆
规格 :
200微升
克隆 :
2A5
产品描述 :
Hsp27 (also known as the Estrogen-Regulated 24k protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPkAP kinase 2 and the stress-activated protein kinase SAPk2 (p38). Hsp27 forms a multimeric complex within cells, and its primary chaperone function, like other small Hsps, appears to be the stabilization of denatured or aggregated proteins in a refolding competent state.
免疫原 :
重组人类Hsp27(1-205aa)纯化来自大肠杆菌
特异性 :
Hsp27
浓度 :
0.1毫克/毫升
储存 :
-20°C (aliquot), Avoid repeated freeze and thaw cycles.
一般参考 :
Ehrnsperger M, et al., (1997) EMBO J 16:221-229 Steve J, et al., (2000) Mol Cell Biol 20(20):7602–7612 Butt E, et al., (2001) J Biol Chem 276:7108-7113 Michael, et al., (2002) Cell Stress Chsperones 7(3):281–296
更多信息或购买 :
公司信息
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
Waltham, MA 02452
info@arp1.com
www.arp1.com800-832-2611 781-373-2182
公司总部: 美国