产品简要
公司名称 :
American Research Products
产品类型 :
抗体
产品名称 :
Anti-Adipophilin / ADRP
目录 :
03-610102
规格 :
200微升
价格 :
129.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
文章摘录数: 1
参考文献
Shepherd S, Cocks M, Tipton K, Ranasinghe A, Barker T, Burniston J, et al. Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5. J Physiol. 2013;591:657-75 pubmed 出版商
产品信息
目录代码 :
03-610102
产品名称 :
Anti-Adipophilin / ADRP
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
纯化
产品类型 :
小鼠单克隆
规格 :
200微升
标价 :
129.00美元
克隆 :
AP 125
抗体亚型 :
IgG1
产品描述 :
Mouse Monoclonal Antibody to Human homologue to mouse adipocyte differentiation-related protein (ADRP). Adipophilin / ADRP is a ubiquitous component of lipid droplets. It has been found in milk fat globule membranes and on the surface of lipid droplets in various cultured cell lines (see e.g. Heid et al.; for review see e.g. Targett- Adams et al.); inducible by etomoxir.Enhanced expression of Adipophilin / ADRP is a useful marker for pathologies characterized by increased lipid droplet accumulation. Such diseases include atheroma, steatosis, obesity and certain cases of liposarcoma. It also seems to be a potent marker for atherosclerosis. ADRP can also be used to study virus entry via lipid droplets (see e.g. Hope et al., Samsa et al.).Polypeptide reacting: Adipophilin / ADRP, MW 48,100 (calculated from aa sequence data); apparent Mr 52,000 (after SDS-PAGE); pI 6.72
免疫原 :
Synthetic peptide (aa 5-27 from N-terminus of human adipophilin)
特异性 :
Adipophilin is positively detected in the glandular cells of lactating mammary gland (ductal cells are negative), zona fasciculata of the adrenal gland, Sertoli cells of the testis, and in fat-accumulating hepatocytes of alcoholic cirrhotic fatty liver; adipocytes are negative.Also positively stained are lipid-storing CD 68-positive macrophages.
应用摘要 :
Immunoblotting (Western blot)Immunohistochemistry of frozen tissue (for staining protocols see ref. Ohsaki et al.)Paraffin-embedded tissue after microwave treatment (for stainingprotocol see Straub et al. 2008), Cytological material
储存 :
2-8°C for immediate use, or at -20°C (aliquot)
一般参考 :
Heid, H.W.et al. (1997) (submitted for publication)Heid, HWet al. (1996) Biochem J. 320: 1025-1030*Steiner, S. et al. (1996). Biochem. Biophys. Res. 218: 777-778Mrozinzki, J et al. (1999) J. Cancer Res&Clin. Oncol. 125 supplementThan, NG et al. (1999) Tumor Biol. 20: 184-192Hope, RG et al. (2000) J. General Virol. 81: 1913-1925Ostermeyer, AG. Et al.(2001) J. Cell Biol. 152: 1071-1078Fujimoto, T. et al. (2001) j. Cell Biol. 152: 1079-1085Buechler, C. et al. (2001) Biochim Biophys Acta 1532: 97-104
更多信息或购买 :
公司信息
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
info@arp1.com
www.arp1.com
800-832-2611 781-373-2182
公司总部: 美国