产品简要
公司名称 :
American Research Products
产品类型 :
抗体
产品名称 :
Anti-p62 Protein (SQSTM1), C-Terminal Specific
目录 :
03-GP62-C
规格 :
25微升
价格 :
169.00美元
克隆性 :
多克隆
宿主 :
豚鼠
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 30
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:100; 图 4b
Watanabe S, Komine O, Endo F, Wakasugi K, Yamanaka K. Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice. J Neurochem. 2018;145:80-89 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1d
Hammerling B, Najor R, Cortez M, Shires S, Leon L, Gonzalez E, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017;8:14050 pubmed 出版商
  • 免疫印迹; 大鼠; 图 4a
Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473:3769-3789 pubmed
  • 免疫组化-石蜡切片; 小鼠; 图 4c
Walker W, Oehler A, Edinger A, Wagner K, Gunn T. Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy. Biol Cell. 2016;108:324-337 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Gschweitl M, Ulbricht A, Barnes C, Enchev R, Stoffel Studer I, Meyer Schaller N, et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. elife. 2016;5:e13841 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s5d
Liu Y, Takahashi Y, Desai N, Zhang J, Serfass J, Shi Y, et al. Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. Sci Rep. 2016;6:20453 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
  • 免疫印迹; 人类; 图 6
Draganov D, Gopalakrishna Pillai S, Chen Y, Zuckerman N, Moeller S, Wang C, et al. Modulation of P2X4/P2X7/Pannexin-1 sensitivity to extracellular ATP via Ivermectin induces a non-apoptotic and inflammatory form of cancer cell death. Sci Rep. 2015;5:16222 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000
Kett L, Stiller B, Bernath M, Tasset I, Blesa J, Jackson Lewis V, et al. α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2. J Neurosci. 2015;35:5724-42 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Lin H, Lin S, Chung Y, Vonderfecht S, Camden J, Flodby P, et al. Dynamic involvement of ATG5 in cellular stress responses. Cell Death Dis. 2014;5:e1478 pubmed 出版商
  • 免疫印迹; 人类; 1:1700
Zhong Y, Morris D, Jin L, Patel M, Karunakaran S, Fu Y, et al. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels. J Biol Chem. 2014;289:26021-37 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
  • 免疫印迹; 小鼠; 1:1000
Lu J, He L, Behrends C, Araki M, Araki K, Jun Wang Q, et al. NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity. Nat Commun. 2014;5:3920 pubmed 出版商
  • 免疫组化; 大鼠; 1:200
  • 免疫印迹; 大鼠; 1:200
Yang S, Xia C, Li S, Du L, Zhang L, Hu Y. Mitochondrial dysfunction driven by the LRRK2-mediated pathway is associated with loss of Purkinje cells and motor coordination deficits in diabetic rat model. Cell Death Dis. 2014;5:e1217 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Lee I, Yun J, Finkel T. The emerging links between sirtuins and autophagy. Methods Mol Biol. 2013;1077:259-71 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 9a
Zhou J, Freeman T, Ahmad F, Shang X, Mangano E, Gao E, et al. GSK-3? is a central regulator of age-related pathologies in mice. J Clin Invest. 2013;123:1821-32 pubmed 出版商
Raso F, Sagadiev S, Du S, Gage E, Arkatkar T, Metzler G, et al. αv Integrins regulate germinal center B cell responses through noncanonical autophagy. J Clin Invest. 2018;128:4163-4178 pubmed 出版商
Pan H, Yan Y, Liu C, Finkel T. The role of ZKSCAN3 in the transcriptional regulation of autophagy. Autophagy. 2017;13:1235-1238 pubmed 出版商
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Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-1269 pubmed 出版商
Tanaka Y, Chambers J, Matsuwaki T, Yamanouchi K, Nishihara M. Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice. Acta Neuropathol Commun. 2014;2:78 pubmed 出版商
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Sishi B, Loos B, van Rooyen J, Engelbrecht A. Autophagy upregulation promotes survival and attenuates doxorubicin-induced cardiotoxicity. Biochem Pharmacol. 2013;85:124-34 pubmed 出版商
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产品信息
目录代码 :
03-GP62-C
产品名称 :
Anti-p62 Protein (SQSTM1), C-Terminal Specific
宿主物种 :
豚鼠
克隆性 :
多克隆
共轭 :
纯化
产品类型 :
豚鼠多克隆
规格 :
25微升
标价 :
169.00美元
产品描述 :
Guinea pig polyclonal to p62 Protein, C-Terminal Specific. Human 62 kD (p62) protein, present in intracytoplasmic inclusions (e.g. hyaline bodies) of hepatocellular carcinoma. P62 protein has been found in many tissues and cells, including lymphoid cells, serving probably a common cellular signal transduction mechanism. The antiserum stains also neurofibrillary tangles in the brain of patients suffering fromAlzheimer’s disease. Note: The p62 antigen might be susceptible to proteolytic degradation. We recommend to use protease inhibitors during sample preparation Synonyms: SQSTM1, Sequestosome 1, Ubiquitin-binding protein
免疫原 :
C-terminal domain (20 amino acids: C-NYD IGA ALD TIQ YSK HPP PL) of human p62 protein, coupled with KLH. This peptide sequence is identical in human, monkey, bovine, mouse, and rat
特异性 :
Human 62 kD (p62) protein, present in intracytoplasmic inclusions (e.g. hyaline bodies) of hepatocellular carcinoma. P62 protein has been found in many tissues and cells, including lymphoid cells, serving probably a common cellular signal transduction mechanism. The antiserum stains also neurofibrillary tangles in the brain of patients suffering from Alzheimer’s disease. Note: The p62 antigen might be susceptible to proteolytic degradation. We recommend to use protease inhibitors during sample preparation.
应用摘要 :
Immunohistochemistry on frozen and paraffin sections (enhanced after microwave treatment) Cytological material Immunoblotting
储存 :
2-8°C
一般参考 :
Stumptner, C. et al. (1999) Am. J. Pathol. 154: 1701-1710Janig, E. et al. (2005) Eur J Cell Biol. 84: 329-339Kuusisto, E. et al. (2007) Neuropathology & Applied Neurobiology, pp 1-12Aishima S et al. (2010) Am J Clin Pathol 134: 457-465Itakura E et al. (2011) J Cell Bio 192: 17-27
更多信息或购买 :
公司信息
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
info@arp1.com
http://www.arp1.com
800-832-2611 781-373-2182
公司总部: 美国