产品简要
公司名称 :
American Research Products
产品类型 :
蛋白
产品名称 :
IL-22
目录 :
19-C047
规格 :
10微克
价格 :
149.00美元
更多信息或购买 :
产品信息
目录代码 :
19-C047
产品名称 :
IL-22
产品类型 :
重组蛋白
规格 :
10微克
标价 :
149.00美元
产品描述 :
Interleukin-22 (IL22), also known as IL-10-related T cell-derived inducible factor (IL-TIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL22 cDNA encodes a 179 amino acid (aa) residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL22 is produced by normal mouse T cells upon Con A activation. Mouse IL22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL22 may be involved in inflammatory responses. The functional IL22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rbeta (previously known as CRF2-4), belonging to the class II cytokine receptor family
纯度 :
Greater than 95% as determined by reducing SDS-PAGE.
包装 :
recombinant mouse IL22 was lyophilized after extensive dialysis against PBS.
更多信息或购买 :
公司信息
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
info@arp1.com
www.arp1.com
800-832-2611 781-373-2182
公司总部: 美国