蛋白

血管内皮生长因子165

19-C083

10微克

149.00美元

血管内皮生长因子165

重组蛋白

10微克

149.00美元

Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cystine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide linked homodimer consisting of two glycosylated 165 a.a polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less-defined and is thought to modulate the VEGFR2 signaling.

Greater than 95% as determined by reducing SDS-PAGE.

Recombinant Human VEGF165 was lyophilized at 1mg/ml in 20mM PBS.