抗体

anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (C-Term) antibody

ABIN264506

0.2毫克

357.5美元

单克隆

小鼠

nonconjugated

1B4

免疫印迹, 免疫组化, 酶免疫法

anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (C-Term) antibody

小鼠

单克隆

基质金属蛋白酶-3

Primary

0.2毫克

357.5美元

3360803,8631328

1B4

IgG1

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including Collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.Synonyms: MMP3, Matrix metalloproteinase-3, SL-1, STMY1, Stromelysin-1, Transin-1

Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the Cterminus of the human MMP3 protein and mousemyeloma Ag8563 cells.

C末端

人类

PBS, 0.08 % 叠氮化钠

酶免疫法(EIA), 免疫组化(石蜡包埋切片)(免疫组化(p)), 免疫印迹(免疫印迹)

P08254