抗体

抗Toll样受体6(TLR6)(C末端)抗体

ABIN357055

0.4毫升

357.5美元

多克隆

兔

nonconjugated

免疫组化, 酶免疫法

抗Toll样受体6(TLR6)(C末端)抗体

兔

多克隆

CD286/TLR6

Primary

0.4毫升

357.5美元

11095740,10231569

Ig

TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.Synonyms: Toll-like receptor 6

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of mouse TLR6.

C末端

Human,Mouse (Murine)

PBS with 0.09 % (W/V) sodium azide

0.25毫克/毫升

酶免疫法(EIA), 免疫组化(石蜡包埋切片)(免疫组化(p))

Q9EPW9