抗体

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pSer727) antibody

ABIN358233

0.4毫升

357.5美元

多克隆

兔

nonconjugated

免疫印迹, 免疫组化, 酶免疫法

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pSer727) antibody

兔

多克隆

STAT3

Primary

0.4毫升

357.5美元

15229229,15184909,15145953,15223310,15207733

Ig

STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. It mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.Synonyms: APRF, Acute-phase response factor, STAT-3, Signal transducer and activator of transcription 3

This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S727 of human STAT3.

pSer727

人类

PBS with 0.09 % (W/V) Sodium Azide as preservative.

0.25毫克/毫升

酶免疫法(EIA), 免疫组化(石蜡包埋切片)(免疫组化(p)), 免疫印迹(免疫印迹)

P40763