抗体

anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (pSer274) antibody

ABIN358242

0.4毫升

357.5美元

多克隆

兔

nonconjugated

人类, 小鼠

免疫印迹, 免疫组化, 酶免疫法

anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (pSer274) antibody

兔

多克隆

CD120a/TNFR1

Primary

0.4毫升

357.5美元

15851552,15818692,15288471,15542843,15502938

Ig

A member of the TNF-receptor superfamily, this protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60

This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S274 of human TNFR.

pSer274

Human,Mouse (Murine)

PBS with 0.09 % (W/V) Sodium Azide as preservative.

0.25毫克/毫升

酶免疫法(EIA), 免疫组化(石蜡包埋切片)(免疫组化(p)), 免疫印迹(免疫印迹)

P19438