产品简要
公司名称 :
Antibodies-online
产品类型 :
抗体
产品名称 :
抗甘油醛3脱氢酶(磷酸甘油醛脱氢酶)(C末端)抗体
目录 :
ABIN374435
规格 :
0.1毫克
价格 :
368.5美元
克隆性 :
多克隆
宿主 :
山羊
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 酶免疫法
更多信息或购买 :
文章摘录数: 5
参考文献
Happold C, Roth P, Silginer M, Florea A, Lamszus K, Frei K, et al. Interferon-? induces loss of spherogenicity and overcomes therapy resistance of glioblastoma stem cells. Mol Cancer Ther. 2014;13:948-61 pubmed 出版商
Happold C, Roth P, Wick W, Schmidt N, Florea A, Silginer M, et al. Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells. J Neurochem. 2012;122:444-55 pubmed 出版商
Kiepe D, Van Der Pas A, Ciarmatori S, Ständker L, Schütt B, Hoeflich A, et al. Defined carboxy-terminal fragments of insulin-like growth factor (IGF) binding protein-2 exert similar mitogenic activity on cultured rat growth plate chondrocytes as IGF-I. Endocrinology. 2008;149:4901-11 pubmed 出版商
Henson M, Roberts A, Salimi K, Vadlamudi S, Hamer R, Gilmore J, et al. Developmental regulation of the NMDA receptor subunits, NR3A and NR1, in human prefrontal cortex. Cereb Cortex. 2008;18:2560-73 pubmed 出版商
Gerstner J, Bremer Q, Vander Heyden W, LaVaute T, Yin J, Landry C. Brain fatty acid binding protein (Fabp7) is diurnally regulated in astrocytes and hippocampal granule cell precursors in adult rodent brain. PLoS ONE. 2008;3:e1631 pubmed 出版商
图像
图像 1 :
Antibodies-online ABIN374435 图像 1
产品信息
目录代码 :
ABIN374435
产品名称 :
抗甘油醛3脱氢酶(磷酸甘油醛脱氢酶)(C末端)抗体
宿主物种 :
山羊
克隆性 :
多克隆
抗原 :
磷酸甘油醛脱氢酶
产品类型 :
Primary
规格 :
0.1毫克
标价美元 :
368.5美元
Pubmed号列表 :
22564186,18556354,18286188,17517966,18296432,20489048,24526161
产品描述 :
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a metabolic enzyme originally thought to be only involved in Glycolysis. GAPDH is constitutively expressed at high levels in almost all tissues and serves therefore as a useful marker for the measurement of equal loading in western blotting experiments. Because of its ubiquitous expression, GAPDH is often seen as a housekeeping gene. However in the last two decades, every year a new function for this enzyme has been revealed. Besides its central role as a cytoplasmic enzyme in Glycolysis, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular processes such as DNA replication and repair, nuclear membrane fusion, endocytosis, nuclear translocation in apoptosis, microtubule bundling, vesicular secretory transport, maintenance of telomere structure, phosphotransferase activity and nuclear RNA export. We now know that GAPDH is not only in the cytoplasm, but it shuttles between the cytoplasm and the nucleus and membranes. A lot of reports demonstrate the role of GAPDH in different pathologies such as progression in prostate cancer and ovarian cancer (mRNA stability), programmed neuronal cell death, and agerelated neuronal diseases. For example the sub-cellular distribution of GAPDH is abnormal in patients with Alzheimer's disease.Synonyms: CDABP0047, GAPD, Glyceraldehyde-3-Phosphate Dehydrogenase
免疫原 :
Peptide with sequence from the C-Terminus of the protein sequence according to NP_002037.2.
表位 :
C末端
反应物种 :
Dog (Canine),Human,Mouse (Murine),Rat (Rattus)
缓冲液 :
Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
浓度 :
0.5毫克/毫升
应用摘要 :
酶免疫法(EIA), 免疫荧光(IF), 免疫组化(石蜡包埋切片)(免疫组化(p)), 免疫印迹(免疫印迹)
UniProt数据库编号 :
P04406
更多信息或购买 :
公司信息
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
support@antibodies-online.com
www.antibodies-online.com
49-0-241-95-163-153
公司总部: 德国
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