产品简要
公司名称 :
Antibodies-online
产品类型 :
抗体
产品名称 :
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) (pSer536) antibody
目录 :
ABIN650886
规格 :
400微升
价格 :
291.5美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
克隆名称 :
RB22552
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
Antibodies-online 产品网页
文章摘录数: 2
参考文献
Pan W, Li J, Huang S, Papadimos T, Pan Z, Chen L. Synergistic activation of NF-{kappa}B by bacterial chemoattractant and TNF{alpha} is mediated by p38 MAPK-dependent RelA acetylation. J Biol Chem. 2010;285:34348-54 pubmed 出版商
Tago K, Funakoshi Tago M, Sakinawa M, Mizuno N, Itoh H. KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA. J Biol Chem. 2010;285:30622-33 pubmed 出版商
图像
图像 1 :
Antibodies-online ABIN650886 图像 1
Dot blot analysis of anti-Phospho-NF kappa B-S536 Phospho-specific Pab (ABIN650886) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6 µg/mL.
产品信息
目录代码 :
ABIN650886
产品名称 :
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) (pSer536) antibody
宿主物种 :
兔
克隆性 :
多克隆
抗原 :
核因子κB
产品类型 :
Primary
规格 :
400微升
标价美元 :
291.5美元
Pubmed号列表 :
20729202,20639196
图像 :
Dot blot analysis of anti-Phospho-NF kappa B-S536 Phospho-specific Pab (ABIN650886) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6 µg/mL.
克隆 :
RB22552
抗体亚型 :
Ig
产品描述 :
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine). Synonyms: Transcription factor p65,RELA,NFKB3
免疫原 :
This NF kappa B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S536 of human NF kappa B.
表位 :
pSer536
反应物种 :
人类
缓冲液 :
PBS with 0.09 % (W/V) sodium azide
浓度 :
0.31毫克/毫升
应用摘要 :
Dot Blot (DB)
UniProt数据库编号 :
Q04206
更多信息或购买 :
Antibodies-online 产品网页
公司信息
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
support@antibodies-online.com
www.antibodies-online.com
49-0-241-95-163-153
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