产品简要
公司名称 :
Antibodies-online
产品类型 :
抗体
产品名称 :
anti-Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) (AA 219-248), (C-Term) antibody
目录 :
ABIN655271
规格 :
400微升
价格 :
291.5美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
克隆名称 :
RB14883
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 流式细胞仪
更多信息或购买 :
文章摘录数: 3
参考文献
Srikanth C, Wall D, Maldonado Contreras A, Shi H, Zhou D, Demma Z, et al. Salmonella pathogenesis and processing of secreted effectors by caspase-3. Science. 2010;330:390-393 pubmed 出版商
Würstle M, Laussmann M, Rehm M. The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signaling. J Biol Chem. 2010;285:33209-18 pubmed 出版商
Burke S, Smith L, Smith J. cIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosome. J Biol Chem. 2010;285:30061-8 pubmed 出版商
图像
图像 1 :
Antibodies-online ABIN655271 图像 1
CASP3 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
产品信息
目录代码 :
ABIN655271
产品名称 :
anti-Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) (AA 219-248), (C-Term) antibody
宿主物种 :
克隆性 :
多克隆
抗原 :
CASP3
产品类型 :
Primary
规格 :
400微升
标价美元 :
291.5美元
Pubmed号列表 :
20702410,20947770,20667824
图像 :
CASP3 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
克隆 :
RB14883
抗体亚型 :
Ig
产品描述 :
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]. Synonyms: Caspase-3,CASP3,CPP32
免疫原 :
This CASP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-248 AA from the C-terminal region of human CASP3.
表位 :
氨基酸219-248, C末端
反应物种 :
人类
缓冲液 :
PBS with 0.09 % (W/V) sodium azide
浓度 :
2毫克/毫升
应用摘要 :
流式细胞仪(流式细胞仪), 免疫组化(石蜡包埋切片)(免疫组化(p)), 免疫印迹(免疫印迹)
UniProt数据库编号 :
P42574
更多信息或购买 :
公司信息
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
support@antibodies-online.com
www.antibodies-online.com
49-0-241-95-163-153
公司总部: 德国
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