产品简要
公司名称 :
Antibodies-online
产品类型 :
抗体
产品名称 :
anti-Wilms Tumor 1 (WT1) (AA 346-375), (Center), (Glu361) antibody
目录 :
ABIN655904
规格 :
400微升
价格 :
291.5美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
克隆名称 :
RB18841
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 流式细胞仪
更多信息或购买 :
文章摘录数: 3
参考文献
Dohi S, Ohno S, Ohno Y, Kyo S, Soma G, Sugiyama H, et al. WT1 expression correlates with angiogenesis in endometrial cancer tissue. Anticancer Res. 2010;30:3187-92 pubmed
Sitaram R, Degerman S, Ljungberg B, Andersson E, Oji Y, Sugiyama H, et al. Wilms' tumour 1 can suppress hTERT gene expression and telomerase activity in clear cell renal cell carcinoma via multiple pathways. Br J Cancer. 2010;103:1255-62 pubmed 出版商
Rocquain J, Carbuccia N, Trouplin V, Raynaud S, Murati A, Nezri M, et al. Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias. BMC Cancer. 2010;10:401 pubmed 出版商
图像
图像 1 :
Antibodies-online ABIN655904 图像 1
Confocal immunofluorescent analysis of WT1 Antibody (Center E361)(ABIN655904) with MCF-7 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
产品信息
目录代码 :
ABIN655904
产品名称 :
anti-Wilms Tumor 1 (WT1) (AA 346-375), (Center), (Glu361) antibody
宿主物种 :
克隆性 :
多克隆
抗原 :
Wilms瘤抑癌基因
产品类型 :
Primary
规格 :
400微升
标价美元 :
291.5美元
Pubmed号列表 :
20842112,20871039,20678218,12665546,9361029
图像 :
Confocal immunofluorescent analysis of WT1 Antibody (Center E361)(ABIN655904) with MCF-7 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
克隆 :
RB18841
抗体亚型 :
Ig
产品描述 :
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq]. Synonyms: WT1,Wilms tumor protein,
免疫原 :
This WT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 AA from the Central region of human WT1.
表位 :
AA 346-375,Center,Glu361
反应物种 :
人类
缓冲液 :
PBS with 0.09 % (W/V) sodium azide
浓度 :
0.3毫克/毫升
应用摘要 :
流式细胞仪(流式细胞仪), 免疫荧光(IF), 免疫组化(石蜡包埋切片)(免疫组化(p)), 免疫印迹(免疫印迹)
UniProt数据库编号 :
P19544
更多信息或购买 :
公司信息
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
support@antibodies-online.com
www.antibodies-online.com
49-0-241-95-163-153
公司总部: 德国
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