抗体

CALR抗体-C末端地区(ARP30114_P050)

ARP30114

100微升

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠, 犬, 斑马鱼

免疫印迹, 免疫组化

多克隆抗体

多克隆

CALR抗体-C末端地区(ARP30114_P050)

100微升

CALR

RO, CRT, SSA, cC1qR

NM_004343

NP_004334

P27797

狗, 山羊, 豚鼠, 马, 人类, 小鼠, 兔, 大鼠, 酵母, 斑马鱼

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

FGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEE
EAEDKEDDEDK
Synthetic peptide located within the following region:

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.

兔

免疫印迹, 免疫组化

Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 92%; Zebrafish: 79%

亲和纯化

多克隆

The immunogen is a synthetic peptide directed towards the C terminal region of human CALR

Wet Ice

-20C