产品简要
公司名称 :
Aviva Systems Biology
产品类型 :
抗体
产品名称 :
NR1I2抗体-N末端地区(ARP36016_P050)
目录 :
ARP36016
规格 :
100微升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
产品信息
SKU号 :
ARP36016
产品类型 :
多克隆抗体
类别 :
多克隆
名称 :
NR1I2抗体-N末端地区(ARP36016_P050)
规格 :
100微升
基因符号 :
NR1I2
alias symbols :
BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
nucleotide accession num :
NM_003889
protein accession num :
NP_003880
SwissProt号 :
O75469
物种活性 :
人类
产品格式 :
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
肽序列 :
KKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEE
QRMMIRELMDA
Synthetic peptide located within the following region:
QRMMIRELMDA
Synthetic peptide located within the following region:
重组和储存 :
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
description of target :
NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. NR1I2 contains a zinc finger domain.NR1I2 is a transcriptional regulator of the cytochrome P45 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P45 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
宿主 :
兔
应用 :
免疫组化, 免疫印迹
同源 :
Human: 100%
纯化 :
亲和纯化
克隆性 :
多克隆
免疫原 :
The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I2
drywet surcharge :
Wet Ice
储存温度 :
-20C
更多信息或购买 :
公司信息
Aviva Systems Biology
7700 Ronson Road, Ste 100, San Diego, CA 92111
techsupport@avivasysbio.com
http://www.avivasysbio.com1-858-552-6979
公司总部: 美国