抗体

STAT3抗体-N末端地区(ARP38253_P050)

ARP38253

100微升

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠, 犬, 牛, 斑马鱼

免疫印迹, 免疫组化, 免疫细胞化学

多克隆抗体

多克隆

STAT3抗体-N末端地区(ARP38253_P050)

100微升

STAT3

APRF, FLJ20882, MGC16063, HIES

NM_003150

NP_003141

B5BTZ6

牛, 狗, 豚鼠, 马, 人类, 小鼠, 兔, 大鼠, 斑马鱼

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

AQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIES
QDWAYAASKES
Synthetic peptide located within the following region:

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. It mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

兔

免疫组化, 免疫印迹, IF

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

亲和纯化

多克隆

The immunogen is a synthetic peptide directed towards the N terminal region of human STAT3

Wet Ice

-20C