抗体

NOTCH1 antibody - middle region (ARP39295_P050)

ARP39295

100微升

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠, 犬, 牛, 斑马鱼

多克隆抗体

多克隆

NOTCH1 antibody - middle region (ARP39295_P050)

100微升

NOTCH1

TAN1, hN1

NM_017617

NP_060087

P46531

牛, 狗, 豚鼠, 马, 人类, 小鼠, 大鼠, 斑马鱼

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

EHPFLTPSPESPDQWSSSSPHSNVSDWSEGVSSPPTSMQ
SQIARIPEAFK
Synthetic peptide located within the following region:

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

NOTCH1 is a member of the Notch family. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

兔

免疫印迹

Cow: 79%; Dog: 79%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 79%; Rat: 93%; Zebrafish: 93%

亲和纯化

多克隆

Antibody recognizes 88 kDa for Notch1 intracellular domain.

The immunogen is a synthetic peptide directed towards the middle region of human NOTCH1

Wet Ice

-20C