产品简要
公司名称 :
Aviva Systems Biology
产品类型 :
抗体
产品名称 :
P4HB抗体-N末端地区(ARP48150_P050)
目录 :
ARP48150
规格 :
100微升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
产品信息
SKU号 :
ARP48150
产品类型 :
多克隆抗体
类别 :
多克隆
名称 :
P4HB抗体-N末端地区(ARP48150_P050)
规格 :
100微升
基因符号 :
P4HB
alias symbols :
DSI, ERBA2L, GIT, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB, P4Hbeta
nucleotide accession num :
NM_000918
protein accession num :
NP_000909
SwissProt号 :
P07237
物种活性 :
牛, 狗, 豚鼠, 马, 人类, 小鼠, 兔, 大鼠
产品格式 :
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
肽序列 :
TIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATT
LPDGAAAESLV
Synthetic peptide located within the following region:
重组和储存 :
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
description of target :
P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
宿主 :
应用 :
免疫组化, 免疫印迹
同源 :
Cow: 100%; Dog: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
纯化 :
亲和纯化
克隆性 :
多克隆
免疫原 :
The immunogen is a synthetic peptide directed towards the N terminal region of human P4HB
drywet surcharge :
Wet Ice
储存温度 :
-20C
更多信息或购买 :
公司信息
Aviva Systems Biology
7700 Ronson Road, Ste 100, San Diego, CA 92111
techsupport@avivasysbio.com
http://www.avivasysbio.com
1-858-552-6979
公司总部: 美国