抗体

PDGFB抗体-N末端地区(ARP58509_P050)

ARP58509

100微升

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠, 犬, 牛

免疫印迹, 免疫组化

多克隆抗体

多克隆

PDGFB抗体-N末端地区(ARP58509_P050)

100微升

PDGFB

FLJ12858, PDGF2, SIS, SSV, c-sis

NM_002608

NP_002599

P01127

牛, 狗, 豚鼠, 人类, 小鼠, 大鼠, 羊

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

NRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRS
FDDLQRLLHGD
Synthetic peptide located within the following region:

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor.The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two splice variants have been identified for this gene.

兔

免疫印迹, 免疫组化

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 100%

亲和纯化

多克隆

The immunogen is a synthetic peptide directed towards the N terminal region of human PDGFB

Wet Ice

-20C