抗体

CASP3抗体-N末端地区(AVARP00021_T100)

AVARP00021

100微升

多克隆

domestic rabbit

未共轭

人类, 大鼠, 犬, 牛

免疫印迹, 免疫组化

多克隆抗体

多克隆

CASP3抗体-N末端地区(AVARP00021_T100)

100微升

CASP3

CPP32, SCA-1, CPP32B

NM_004346

NP_004337

P42574

牛, 狗, 豚鼠, 马, 人类, 猪, 兔, 大鼠

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKM
DYPEMGLCIII
Synthetic peptide located within the following region:

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 1. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

兔

免疫组化, 免疫印迹

Cow: 84%; Dog: 84%; Guinea Pig: 84%; Horse: 92%; Human: 100%; Pig: 92%; Rabbit: 84%; Rat: 84%

蛋白质A纯化

多克隆

The immunogen is a synthetic peptide directed towards the N terminal region of human CASP3

Wet Ice

-20C