产品简要
公司名称 :
Aviva Systems Biology
产品类型 :
ELISA/assay
产品名称 :
VEGFA ELISA Kit (Human) : 48 Wells (OKAA00029-48W)
目录 :
OKAA00029
规格 :
48 Wells
更多信息或购买 :
产品信息
SKU号 :
OKAA00029
产品类型 :
Application Kit
类别 :
酶联免疫吸附试剂盒
名称 :
VEGFA ELISA Kit (Human) : 48 Wells (OKAA00029-48W)
规格 :
48 Wells
基因符号 :
血管内皮生长因子A
alias symbols :
MGC70609, MVCD1, 血管内皮生长因子, 血管通透性因子, 血管内皮生长因子, 血管内皮生长因子-A, VPF
nucleotide accession num :
NM_001025366.2
protein accession num :
NP_001020537.2
SwissProt号 :
P15692
物种活性 :
人类
description of target :
This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.
应用 :
酶联免疫吸附测定
同源 :
人类
assay info :
Assay Method: Quantitative Sandwich ELISA
敏感性 :
7 pg/ml
特异性 :
This assay recognizes both natural and recombinant human TSLP. The factors listed below were prepared at 50ng/ml in Standard /sample Diluent and assayed for cross-reactivity and no significant cross-reactivity or interference was observed.Recombinant human: IL-1a, IL-1b, IL-2, IL-3, IL-4, IL-5, IL-6 , Recombinant mouse: IL-1a, IL-1b, IL-2, IL-4, IL-5, IL-6 , Recombinant rat: IL-1a , IL-1b, IL-2, IL-4, IL-6, IL-10, Leptin ,
drywet surcharge :
Wet Ice
储存温度 :
4C
更多信息或购买 :
公司信息
Aviva Systems Biology
7700 Ronson Road, Ste 100, San Diego, CA 92111
techsupport@avivasysbio.com
http://www.avivasysbio.com
1-858-552-6979
公司总部: 美国