ELISA/assay

STAT3脱氧核糖核酸结合酶联免疫吸附试剂盒(OKAG00467)

OKAG00467

96试验

Application Kit

酶联免疫吸附试剂盒

STAT3脱氧核糖核酸结合酶联免疫吸附试剂盒(OKAG00467)

96试验

STAT3

Acute-phase response factor, APRF, FLJ20882, HIES, MGC16063, Signal transducer and activator of transcription 3

P40763

人类, 小鼠, 大鼠

12 x 8-Well Microstrips

Store as indicated in product manual.

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

酶联免疫吸附测定

Assay Type: Qualitative DNA Binding ELISA

STAT3脱氧核糖核酸结合酶联免疫吸附测定检测内生水平总数STAT3蛋白

Wet Ice

4C