ELISA/assay

SEMA4D酶联免疫吸附试剂盒(小鼠)(OKCD02880)

OKCD02880

96 Wells

Application Kit

酶联免疫吸附试剂盒

SEMA4D酶联免疫吸附试剂盒(小鼠)(OKCD02880)

96 Wells

SEMA4D

CD100, coll-4, M-sema G, M-Sema G, Semacl2, Semaj, Sema J, Semaphorin-4D, Semaphorin-C-like 2, semaphorin H, Semaphorin-J, Semcl2

NM_001281880.1

NP_001268809.1

O09126

小鼠

Store as indicated in product manual.

Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

Assay Methodology: Quantitative Sandwich ELISA

0.30 ng/mL

This assay has high sensitivity and excellent specificity for detection of Semaphorin 4D (SEMA4D). No significant cross-reactivity or interference between Semaphorin 4D (SEMA4D) and analogues was observed

Wet Ice

2-8C