产品简要
公司名称 :
碧迪BD
其他品牌 :
Transduction Laboratories, PharMingen, Difco
产品类型 :
抗体
产品名称 :
CD3e
目录 :
557306
规格 :
0.1毫克
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
未共轭
克隆名称 :
145-2C11
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片, 抑制或激活实验, 其他
更多信息或购买 :
文章摘录数: 407
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 3a
Chuang H, Chen M, Chen Y, Yang H, Ciou Y, Hsueh C, et al. BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus. Theranostics. 2021;11:9953-9966 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Zhu Y, Elsheikha H, Wang J, Fang S, He J, Zhu X, et al. Synergy between Toxoplasma gondii type I ΔGRA17 immunotherapy and PD-L1 checkpoint inhibition triggers the regression of targeted and distal tumors. J Immunother Cancer. 2021;9: pubmed 出版商
  • 免疫组化; 小鼠; 1:300; 图 s3ci
Papazian I, Tsoukala E, Boutou A, Karamita M, Kambas K, Iliopoulou L, et al. Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice. J Neuroinflammation. 2021;18:222 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s5a
Liu Y, Du J, Liu X, Wang L, Han Y, Huang C, et al. MG149 inhibits histone acetyltransferase KAT8-mediated IL-33 acetylation to alleviate allergic airway inflammation and airway hyperresponsiveness. Signal Transduct Target Ther. 2021;6:321 pubmed 出版商
  • 流式细胞仪; 小鼠
Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400; 图 2i
Roca C, Burton O, Gergelits V, Prezzemolo T, Whyte C, Halpert R, et al. AutoSpill is a principled framework that simplifies the analysis of multichromatic flow cytometry data. Nat Commun. 2021;12:2890 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5f
Yang C, Kwon D, Kim M, Im S, Lee Y. Commensal Microbiome Expands Tγδ17 Cells in the Lung and Promotes Particulate Matter-Induced Acute Neutrophilia. Front Immunol. 2021;12:645741 pubmed 出版商
  • 流式细胞仪; 小鼠
Jhala G, Selck C, Chee J, Kwong C, Pappas E, Thomas H, et al. Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice. Front Immunol. 2021;12:645817 pubmed 出版商
  • 抑制或激活实验; 小鼠; 2 ug/ml; 图 6b
Petty A, Dai R, Lapalombella R, Baiocchi R, Benson D, Li Z, et al. Hedgehog-induced PD-L1 on tumor-associated macrophages is critical for suppression of tumor-infiltrating CD8+ T cell function. JCI Insight. 2021;6: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Sciarrillo R, Di Lorenzo M, Valiante S, Rosati L, De Falco M. OctylPhenol (OP) Alone and in Combination with NonylPhenol (NP) Alters the Structure and the Function of Thyroid Gland of the Lizard Podarcis siculus. Arch Environ Contam Toxicol. 2021;80:567-578 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Lee D, Lin Y, Chang G. Biochemical Regulation of the Glyoxalase System in Response to Insulin Signaling. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Chen Z, Lin X, Chan T, Chan H. Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis. Aging (Albany NY). 2021;13:7259-7283 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Chiavellini P, Canatelli Mallat M, Lehmann M, Gallardo M, Herenu C, Cordeiro J, et al. Aging and rejuvenation - a modular epigenome model. Aging (Albany NY). 2021;13:4734-4746 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Schiessl J, Kosciow K, Garschagen L, Hoffmann J, Heymuth J, Franke T, et al. Degradation of the low-calorie sugar substitute 5-ketofructose by different bacteria. Appl Microbiol Biotechnol. 2021;105:2441-2453 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Kvacskay P, Yao N, Schnotz J, Scarpone R, Carvalho R, Klika K, et al. Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?. Arthritis Res Ther. 2021;23:56 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Mpekris F, Panagi M, Voutouri C, Martin J, Samuel R, Takahashi S, et al. Normalizing the Microenvironment Overcomes Vessel Compression and Resistance to Nano-immunotherapy in Breast Cancer Lung Metastasis. Adv Sci (Weinh). 2021;8:2001917 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100
Wang Y, Yang Y, Wang M, Wang S, Jeong J, Xu L, et al. Eosinophils attenuate hepatic ischemia-reperfusion injury in mice through ST2-dependent IL-13 production. Sci Transl Med. 2021;13: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Zhao L, Hu S, Davila M, Yang J, Lin Y, Albanese J, et al. Coordinated co-migration of CCR10+ antibody-producing B cells with helper T cells for colonic homeostatic regulation. Mucosal Immunol. 2021;14:420-430 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 1j
Castiello M, Bosticardo M, Sacchetti N, Calzoni E, Fontana E, Yamazaki Y, et al. Efficacy and safety of anti-CD45-saporin as conditioning agent for RAG deficiency. J Allergy Clin Immunol. 2021;147:309-320.e6 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 8a
Grand M, Waqasi M, Demarta Gatsi C, Wei Y, Peronet R, Commere P, et al. Hepatic Inflammation Confers Protective Immunity Against Liver Stages of Malaria Parasite. Front Immunol. 2020;11:585502 pubmed 出版商
  • 流式细胞仪; 小鼠
Shi H, Lo T, Ma D, Condor B, Lesmana B, Parungao R, et al. Dihydrotestosterone (DHT) Enhances Wound Healing of Major Burn Injury by Accelerating Resolution of Inflammation in Mice. Int J Mol Sci. 2020;21: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:300; 图 4n
Stebegg M, Bignon A, Hill D, Silva Cayetano A, Krueger C, Vanderleyden I, et al. Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1m
  • 免疫组化; 小鼠
Choi S, Bae H, Jeong S, Park I, Cho H, Hong S, et al. YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells. Nat Commun. 2020;11:519 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 e9g
Song E, Mao T, Dong H, Boisserand L, Antila S, Bosenberg M, et al. VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours. Nature. 2020;577:689-694 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Cheng M, Chen Y, Huang D, Chen W, Xu W, Chen Y, et al. Intrinsically altered lung-resident γδT cells control lung melanoma by producing interleukin-17A in the elderly. Aging Cell. 2020;19:e13099 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s5
Bell O, Copland D, Ward A, Nicholson L, Lange C, Chu C, et al. Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Front Immunol. 2019;10:3033 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2f
Williford J, Ishihara J, Ishihara A, Mansurov A, Hosseinchi P, Marchell T, et al. Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy. Sci Adv. 2019;5:eaay1357 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2d
Zhao Y, Yang Q, Jin C, Feng Y, Xie S, Xie H, et al. Changes of CD103-expressing pulmonary CD4+ and CD8+ T cells in S. japonicum infected C57BL/6 mice. BMC Infect Dis. 2019;19:999 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 s5a, s6a
Ansaldo E, Slayden L, Ching K, Koch M, Wolf N, Plichta D, et al. Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasis. Science. 2019;364:1179-1184 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2c
Sharma N, Vacher J, Allison J. TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion. Proc Natl Acad Sci U S A. 2019;116:10453-10462 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 e8a
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4d
Yamamoto T, Lee P, Vodnala S, Gurusamy D, Kishton R, Yu Z, et al. T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy. J Clin Invest. 2019;129:1551-1565 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Mikolajczyk T, Nosalski R, Skiba D, Koziol J, Mazur M, Justo Junior A, et al. 1,2,3,4,6-Penta-O-galloyl-β-d-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. Br J Pharmacol. 2019;176:1951-1965 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Martins J, Andoniou C, Fleming P, Kuns R, Schuster I, Voigt V, et al. Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantation. Science. 2019;363:288-293 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Li J, He Y, Hao J, Ni L, Dong C. High Levels of Eomes Promote Exhaustion of Anti-tumor CD8+ T Cells. Front Immunol. 2018;9:2981 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Farhat K, Bodart G, Charlet Renard C, Desmet C, Moutschen M, Beguin Y, et al. Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae. Front Immunol. 2018;9:2175 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3b
Noh J, Kim Y, Kim D, Hwang J, Kim K, Choi D, et al. Small heterodimer partner negatively regulates C-X-C motif chemokine ligand 2 in hepatocytes during liver inflammation. Sci Rep. 2018;8:15222 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Qu J, Li L, Xie H, Zhang X, Yang Q, Qiu H, et al. TLR3 Modulates the Response of NK Cells against Schistosoma japonicum. J Immunol Res. 2018;2018:7519856 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Li H, Li D, He Z, Fan J, Li Q, Liu X, et al. The effects of Nrf2 knockout on regulation of benzene-induced mouse hematotoxicity. Toxicol Appl Pharmacol. 2018;358:56-67 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
White E, Gyulay G, Lhotak S, Szewczyk M, Chong T, Fuller M, et al. Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice. J Biol Chem. 2018;293:14689-14706 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Feng Y, Liao Y, Huang W, Lai X, Luo J, Du C, et al. Mesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis. Cell Death Dis. 2018;9:691 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5d
Stefani F, Eberstål S, Vergani S, Kristiansen T, Bengzon J. Low-dose irradiated mesenchymal stromal cells break tumor defensive properties in vivo. Int J Cancer. 2018;143:2200-2212 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Lee J, Park J, Nam T, Seo S, Kim J, Lee H, et al. Differences between immunodeficient mice generated by classical gene targeting and CRISPR/Cas9-mediated gene knockout. Transgenic Res. 2018;27:241-251 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2a
Kara E, Bastow C, McKenzie D, Gregor C, Fenix K, Babb R, et al. Atypical chemokine receptor 4 shapes activated B cell fate. J Exp Med. 2018;215:801-813 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Zhang Y, Khairallah C, Sheridan B, van der Velden A, Bliska J. CCR2+ Inflammatory Monocytes Are Recruited to Yersinia pseudotuberculosis Pyogranulomas and Dictate Adaptive Responses at the Expense of Innate Immunity during Oral Infection. Infect Immun. 2018;86: pubmed 出版商
  • 抑制或激活实验; 小鼠; 0.5 ug/ml; 图 3c
Johnson R, Yu H, Strank N, Karunakaran K, Zhu Y, Brunham R. B Cell Presentation of Chlamydia Antigen Selects Out Protective CD4?13 T Cells: Implications for Genital Tract Tissue-Resident Memory Lymphocyte Clusters. Infect Immun. 2018;86: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Muschaweckh A, Petermann F, Korn T. IL-1? and IL-23 Promote Extrathymic Commitment of CD27+CD122- ?? T Cells to ??T17 Cells. J Immunol. 2017;199:2668-2679 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 9a
Miao T, Symonds A, Singh R, Symonds J, Ogbe A, Omodho B, et al. Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017;214:1787-1808 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Laffont S, Blanquart E, Savignac M, Cenac C, Laverny G, Metzger D, et al. Androgen signaling negatively controls group 2 innate lymphoid cells. J Exp Med. 2017;214:1581-1592 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Kwan B, Zhu E, Tzeng A, Sugito H, Eltahir A, Ma B, et al. Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses. J Exp Med. 2017;214:1679-1690 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Singh R, Miao T, Symonds A, Omodho B, Li S, Wang P. Egr2 and 3 Inhibit T-bet-Mediated IFN-? Production in T Cells. J Immunol. 2017;198:4394-4402 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Kim W, Kim M, Kim D, Byun J, Huy H, Song H, et al. Suppressor of Cytokine Signaling 2 Negatively Regulates NK Cell Differentiation by Inhibiting JAK2 Activity. Sci Rep. 2017;7:46153 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4
Oh J, Oh D, Jung H, Lee H. A mechanism for the induction of type 2 immune responses by a protease allergen in the genital tract. Proc Natl Acad Sci U S A. 2017;114:E1188-E1195 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Vander Lugt B, Riddell J, Khan A, Hackney J, Lesch J, DeVoss J, et al. Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation. J Cell Biol. 2017;216:779-792 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Ishiguro T, Fukawa T, Akaki K, Nagaoka K, Takeda T, Iwakura Y, et al. Absence of DCIR1 reduces the mortality rate of endotoxemic hepatitis in mice. Eur J Immunol. 2017;47:704-712 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Yanagita T, Murata Y, Tanaka D, Motegi S, Arai E, Daniwijaya E, et al. Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy. JCI Insight. 2017;2:e89140 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 s1
Nowyhed H, Chandra S, Kiosses W, Marcovecchio P, Andary F, Zhao M, et al. ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content. Sci Rep. 2017;7:40273 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4b
Jiang X, Park C, Geddes Sweeney J, Yoo M, Gaide O, Kupper T. Dermal ?? T Cells Do Not Freely Re-Circulate Out of Skin and Produce IL-17 to Promote Neutrophil Infiltration during Primary Contact Hypersensitivity. PLoS ONE. 2017;12:e0169397 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4b
Ellman D, Degn M, Lund M, Clausen B, Novrup H, Flæng S, et al. Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice. Mediators Inflamm. 2016;2016:2684098 pubmed 出版商
  • 抑制或激活实验; 小鼠
Rampoldi F, Brunk F, Bonrouhi M, Federico G, Krunic D, Porubsky S, et al. Deficiency of N-myristoylation reveals calcineurin activity as regulator of IFN-?-producing ?? T cells. J Leukoc Biol. 2017;101:1005-1014 pubmed 出版商
  • 抑制或激活实验; 小鼠
  • 流式细胞仪; 小鼠
Hayakawa M, Hayakawa H, Petrova T, Ritprajak P, Sutavani R, Jiménez Andrade G, et al. Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction. J Biol Chem. 2017;292:1762-1772 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4b
Li M, Li Z, Yao Y, Jin W, Wood K, Liu Q, et al. Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity. Proc Natl Acad Sci U S A. 2017;114:E396-E405 pubmed 出版商
  • 抑制或激活实验; 小鼠; 2 ug/ml; 图 3b
Morita K, Okamura T, Inoue M, Komai T, Teruya S, Iwasaki Y, et al. Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-β3 production. Proc Natl Acad Sci U S A. 2016;113:E8131-E8140 pubmed
  • 流式细胞仪; 小鼠; 图 3d
Sektioglu I, Carretero R, Bulbuc N, Bald T, Tüting T, Rudensky A, et al. Basophils Promote Tumor Rejection via Chemotaxis and Infiltration of CD8+ T Cells. Cancer Res. 2017;77:291-302 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 s3c
Hammer A, Yang G, Friedrich J, Kovacs A, Lee D, Grave K, et al. Role of the receptor Mas in macrophage-mediated inflammation in vivo. Proc Natl Acad Sci U S A. 2016;113:14109-14114 pubmed
  • 流式细胞仪; 小鼠
Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Jirmo A, Daluege K, Happle C, Albrecht M, Dittrich A, Busse M, et al. IL-27 Is Essential for Suppression of Experimental Allergic Asthma by the TLR7/8 Agonist R848 (Resiquimod). J Immunol. 2016;197:4219-4227 pubmed
  • 抑制或激活实验; 小鼠
Paszkiewicz P, Fräßle S, Srivastava S, Sommermeyer D, Hudecek M, Drexler I, et al. Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia. J Clin Invest. 2016;126:4262-4272 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Alves da Costa T, Di Gangi R, Thomé R, Barreto Felisbino M, Pires Bonfanti A, Lumi Watanabe Ishikawa L, et al. Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis. PLoS ONE. 2016;11:e0164745 pubmed 出版商
  • 免疫细胞化学; 小鼠
Wang H, Li M, Hung C, Sinha M, Lee L, Wiesner D, et al. MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase. PLoS Pathog. 2016;12:e1005787 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Lebrero Fernández C, Bas Forsberg A. The ontogeny of Butyrophilin-like (Btnl) 1 and Btnl6 in murine small intestine. Sci Rep. 2016;6:31524 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Drake L, Iijima K, Bartemes K, Kita H. Group 2 Innate Lymphoid Cells Promote an Early Antibody Response to a Respiratory Antigen in Mice. J Immunol. 2016;197:1335-42 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4e
Clausen B, Degn M, Sivasaravanaparan M, Fogtmann T, Andersen M, Trojanowsky M, et al. Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling. Sci Rep. 2016;6:29291 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Lo T, Silveira P, Fromm P, Verma N, Vu P, Kupresanin F, et al. Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. J Immunol. 2016;197:885-98 pubmed 出版商
  • 抑制或激活实验; 小鼠; 1 ug/ml; 图 3
Gu L, Deng W, Sun X, Zhou H, Xu Q. Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance. Mol Med Rep. 2016;14:1153-61 pubmed 出版商
  • 流式细胞仪; 人类; 图 s3a
Yamashita K, Kawata K, Matsumiya H, Kamekura R, Jitsukawa S, Nagaya T, et al. Bob1 limits cellular frequency of T-follicular helper cells. Eur J Immunol. 2016;46:1361-70 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1f
Holmkvist P, Pool L, Hägerbrand K, Agace W, Rivollier A. IL-18R?-deficient CD4(+) T cells induce intestinal inflammation in the CD45RB(hi) transfer model of colitis despite impaired innate responsiveness. Eur J Immunol. 2016;46:1371-82 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Fend L, Remy Ziller C, Foloppe J, Kempf J, Cochin S, Barraud L, et al. Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment. Oncoimmunology. 2016;5:e1080414 pubmed
  • 流式细胞仪; 小鼠; 图 s1
Sim C, Cho Y, Kim B, Baek I, Kim Y, Lee M. 2'-5' Oligoadenylate synthetase-like 1 (OASL1) deficiency in mice promotes an effective anti-tumor immune response by enhancing the production of type I interferons. Cancer Immunol Immunother. 2016;65:663-75 pubmed 出版商
  • 流式细胞仪; 小鼠
Cordeiro O, Chypre M, Brouard N, Rauber S, Alloush F, Romera Hernandez M, et al. Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL. PLoS ONE. 2016;11:e0151848 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Lombard R, Doz E, Carreras F, Epardaud M, Le Vern Y, Buzoni Gatel D, et al. IL-17RA in Non-Hematopoietic Cells Controls CXCL-1 and 5 Critical to Recruit Neutrophils to the Lung of Mycobacteria-Infected Mice during the Adaptive Immune Response. PLoS ONE. 2016;11:e0149455 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1, 2
Kim J, Choi Y, Lee B, Song M, Ban C, Kim J, et al. Programmed cell death ligand 1 alleviates psoriatic inflammation by suppressing IL-17A production from programmed cell death 1-high T cells. J Allergy Clin Immunol. 2016;137:1466-1476.e3 pubmed 出版商
  • 抑制或激活实验; 小鼠; 0.25 ug/ml
Bandyopadhyay S, Quinn T, Scandiuzzi L, Basu I, Partanen A, Tomé W, et al. Low-Intensity Focused Ultrasound Induces Reversal of Tumor-Induced T Cell Tolerance and Prevents Immune Escape. J Immunol. 2016;196:1964-76 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2
Scholz A, Harter P, Cremer S, Yalcin B, Gurnik S, Yamaji M, et al. Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma. EMBO Mol Med. 2016;8:39-57 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Majumder K, Arora N, Modi S, Chugh R, Nomura A, Giri B, et al. A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies. J Gastrointest Surg. 2016;20:53-65; discussion 65 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Okada K, Sato S, Sato A, Mandelboim O, Yamasoba T, Kiyono H. Identification and Analysis of Natural Killer Cells in Murine Nasal Passages. PLoS ONE. 2015;10:e0142920 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 3i
Alam M, Gaida M, Bergmann F, Lasitschka F, Giese T, Giese N, et al. Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression. Nat Med. 2015;21:1337-43 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Vlachou K, Mintzas K, Glymenaki M, Ioannou M, Papadaki G, Bertsias G, et al. Elimination of Granulocytic Myeloid-Derived Suppressor Cells in Lupus-Prone Mice Linked to Reactive Oxygen Species-Dependent Extracellular Trap Formation. Arthritis Rheumatol. 2016;68:449-61 pubmed 出版商
  • 流式细胞仪; 大鼠; 图 4b
Fichtner A, Paletta D, Starick L, Schumann R, Niewiesk S, Herrmann T. Function and expression of CD1d and invariant natural killer T-cell receptor in the cotton rat (Sigmodon hispidus). Immunology. 2015;146:618-29 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Poncini C, Ilarregui J, Batalla E, Engels S, Cerliani J, Cucher M, et al. Trypanosoma cruzi Infection Imparts a Regulatory Program in Dendritic Cells and T Cells via Galectin-1-Dependent Mechanisms. J Immunol. 2015;195:3311-24 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6a
Kaminsky L, Sei J, Parekh N, Davies M, Reider I, Krouse T, et al. Redundant Function of Plasmacytoid and Conventional Dendritic Cells Is Required To Survive a Natural Virus Infection. J Virol. 2015;89:9974-85 pubmed 出版商
  • 流式细胞仪; 人类
  • 流式细胞仪; 小鼠
Holtzhausen A, Zhao F, Evans K, Tsutsui M, Orabona C, Tyler D, et al. Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy. Cancer Immunol Res. 2015;3:1082-95 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:65; 图 s2
Castiglioni A, Corna G, Rigamonti E, Basso V, Vezzoli M, Monno A, et al. FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration. PLoS ONE. 2015;10:e0128094 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1b
Weigelin B, Bolaños E, Teijeira A, Martinez Forero I, Labiano S, Azpilikueta A, et al. Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb. Proc Natl Acad Sci U S A. 2015;112:7551-6 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Bouchery T, Kyle R, Camberis M, Shepherd A, Filbey K, Smith A, et al. ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms. Nat Commun. 2015;6:6970 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Wirsdörfer F, Bangen J, Pastille E, Hansen W, Flohé S. Breaking the co-operation between bystander T-cells and natural killer cells prevents the development of immunosuppression after traumatic skeletal muscle injury in mice. Clin Sci (Lond). 2015;128:825-38 pubmed 出版商
  • 其他; 小鼠; 图 8
Liesz A, Dalpke A, Mracskó É, Antoine D, Roth S, Zhou W, et al. DAMP signaling is a key pathway inducing immune modulation after brain injury. J Neurosci. 2015;35:583-98 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Pekkonen P, Järviluoma A, Zinovkina N, Cvrljevic A, Prakash S, Westermarck J, et al. KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo. Cell Cycle. 2014;13:3670-84 pubmed 出版商
  • 流式细胞仪; 小鼠
Nacer A, Movila A, Sohet F, Girgis N, Gundra U, Loke P, et al. Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier. PLoS Pathog. 2014;10:e1004528 pubmed 出版商
  • 抑制或激活实验; 小鼠
Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 2015;518:417-21 pubmed 出版商
  • 流式细胞仪; 小鼠
Peters A, Burkett P, Sobel R, Buckley C, Watson S, Bettelli E, et al. Podoplanin negatively regulates CD4+ effector T cell responses. J Clin Invest. 2015;125:129-40 pubmed 出版商
  • 流式细胞仪; 小鼠
Venkatanarayan A, Raulji P, Norton W, Chakravarti D, Coarfa C, Su X, et al. IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo. Nature. 2015;517:626-30 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Mehta P, Nuotio Antar A, Smith C. γδ T cells promote inflammation and insulin resistance during high fat diet-induced obesity in mice. J Leukoc Biol. 2015;97:121-34 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Behler F, Maus R, Bohling J, Knippenberg S, Kirchhof G, Nagata M, et al. Macrophage-inducible C-type lectin Mincle-expressing dendritic cells contribute to control of splenic Mycobacterium bovis BCG infection in mice. Infect Immun. 2015;83:184-96 pubmed 出版商
  • 免疫组化; 小鼠; 图 7
Donaldson D, Bradford B, Artis D, Mabbott N. Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23. Mucosal Immunol. 2015;8:582-95 pubmed 出版商
  • 流式细胞仪; 小鼠
Tassi I, Claudio E, Wang H, Tang W, Ha H, Saret S, et al. The NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunity. J Immunol. 2014;193:4303-11 pubmed 出版商
  • 流式细胞仪; 小鼠
Wei F, Yang D, Tewary P, Li Y, Li S, Chen X, et al. The Alarmin HMGN1 contributes to antitumor immunity and is a potent immunoadjuvant. Cancer Res. 2014;74:5989-98 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Naik E, Webster J, DeVoss J, Liu J, Suriben R, Dixit V. Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X. J Exp Med. 2014;211:1947-55 pubmed 出版商
  • 流式细胞仪; 小鼠
Wei H, Nash W, Makrigiannis A, Brown M. Impaired NK-cell education diminishes resistance to murine CMV infection. Eur J Immunol. 2014;44:3273-82 pubmed 出版商
  • 流式细胞仪; 小鼠
Wu C, He S, Peng Y, Kushwaha K, Lin J, Dong J, et al. TSLPR deficiency attenuates atherosclerotic lesion development associated with the inhibition of TH17 cells and the promotion of regulator T cells in ApoE-deficient mice. J Mol Cell Cardiol. 2014;76:33-45 pubmed 出版商
  • 抑制或激活实验; 人类; 1 ug/ml
Lin C, Lo S, Hsu C, Hsieh C, Chang Y, Hou B, et al. T-cell autophagy deficiency increases mortality and suppresses immune responses after sepsis. PLoS ONE. 2014;9:e102066 pubmed 出版商
  • 流式细胞仪; 小鼠
Siurala M, Bramante S, Vassilev L, Hirvinen M, Parviainen S, Tähtinen S, et al. Oncolytic adenovirus and doxorubicin-based chemotherapy results in synergistic antitumor activity against soft-tissue sarcoma. Int J Cancer. 2015;136:945-54 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Alsadeq A, Hobeika E, Medgyesi D, Kläsener K, Reth M. The role of the Syk/Shp-1 kinase-phosphatase equilibrium in B cell development and signaling. J Immunol. 2014;193:268-76 pubmed 出版商
  • 流式细胞仪; 小鼠
Vargas A, Zhou S, Ethier Chiasson M, Flipo D, Lafond J, Gilbert C, et al. Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia. FASEB J. 2014;28:3703-19 pubmed 出版商
  • 流式细胞仪; 小鼠
Jakobsson T, Vedin L, Hassan T, Venteclef N, Greco D, D AMATO M, et al. The oxysterol receptor LXR? protects against DSS- and TNBS-induced colitis in mice. Mucosal Immunol. 2014;7:1416-28 pubmed 出版商
  • 流式细胞仪; 小鼠; 表 1
Okimura K, Maeta K, Kobayashi N, Goto M, Kano N, Ishihara T, et al. Characterization of ASKP1240, a fully human antibody targeting human CD40 with potent immunosuppressive effects. Am J Transplant. 2014;14:1290-9 pubmed 出版商
  • 抑制或激活实验; 小鼠; 0.5 ug/ml
Ntranos A, Hall O, Robinson D, Grishkan I, Schott J, Tosi D, et al. FTY720 impairs CD8 T-cell function independently of the sphingosine-1-phosphate pathway. J Neuroimmunol. 2014;270:13-21 pubmed 出版商
  • 流式细胞仪; 小鼠
Hirayama T, Asano Y, Iida H, Watanabe T, Nakamura T, Goitsuka R. Meis1 is required for the maintenance of postnatal thymic epithelial cells. PLoS ONE. 2014;9:e89885 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Gaughan A, Wang J, Pelletier R, Nadasdy T, Brodsky S, Roy S, et al. Key role for CD4 T cells during mixed antibody-mediated rejection of renal allografts. Am J Transplant. 2014;14:284-94 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Bignon A, Gaudin F, Hemon P, Tharinger H, Mayol K, Walzer T, et al. CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice. J Immunol. 2014;192:886-96 pubmed 出版商
  • 抑制或激活实验; 小鼠; 10 ug/ml
Lee P, Puppi M, Schluns K, Yu Lee L, Dong C, Lacorazza H. The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineage. J Immunol. 2014;192:178-88 pubmed 出版商
  • 抑制或激活实验; 小鼠; 1 ug/ml
Iwata A, Kawashima S, Kobayashi M, Okubo A, Kawashima H, Suto A, et al. Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity. Int Immunol. 2014;26:103-14 pubmed 出版商
  • 抑制或激活实验; 小鼠; 10 ug/ml
Sumitomo S, Fujio K, Okamura T, Morita K, Ishigaki K, Suzukawa K, et al. Transcription factor early growth response 3 is associated with the TGF-?1 expression and the regulatory activity of CD4-positive T cells in vivo. J Immunol. 2013;191:2351-9 pubmed 出版商
  • 流式细胞仪; 小鼠
Erlandsson M, Svensson M, Jonsson I, Bian L, Ambartsumian N, Andersson S, et al. Expression of metastasin S100A4 is essential for bone resorption and regulates osteoclast function. Biochim Biophys Acta. 2013;1833:2653-2663 pubmed 出版商
  • 流式细胞仪; 小鼠
Qiao G, Zhao Y, Li Z, Tang P, Langdon W, Yang T, et al. T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells. J Immunol. 2013;191:632-9 pubmed 出版商
  • 抑制或激活实验; 小鼠; 1 ug/ml; 图 2
Dufner A, Schamel W. B cell antigen receptor-induced activation of an IRAK4-dependent signaling pathway revealed by a MALT1-IRAK4 double knockout mouse model. Cell Commun Signal. 2011;9:6 pubmed 出版商
  • 流式细胞仪; 小鼠
Blache C, Adriouch S, Calbo S, Drouot L, Dulauroy S, Arnoult C, et al. Cutting edge: CD4-independent development of functional FoxP3+ regulatory T cells. J Immunol. 2009;183:4182-6 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Godfrey D, Kennedy J, Mombaerts P, Tonegawa S, Zlotnik A. Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. J Immunol. 1994;152:4783-92 pubmed
Zhu Q, Ma Y, Liang J, Wei Z, Li M, Zhang Y, et al. AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma. Signal Transduct Target Ther. 2021;6:299 pubmed 出版商
Liu S, Lei Z, Li J, Wang L, Jia R, Liu Z, et al. Interleukin 16 contributes to gammaherpesvirus pathogenesis by inhibiting viral reactivation. PLoS Pathog. 2020;16:e1008701 pubmed 出版商
Wu Y, Chou T, Young L, Hsieh F, Pan H, Mo S, et al. Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation. Cell Death Dis. 2020;11:305 pubmed 出版商
Okumura G, Iguchi Manaka A, Murata R, Yamashita Kanemaru Y, Shibuya A, Shibuya K. Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells. J Exp Med. 2020;217: pubmed 出版商
Khumalo J, Kirstein F, Scibiorek M, Hadebe S, Brombacher F. Therapeutic and prophylactic deletion of IL-4Ra-signaling ameliorates established ovalbumin induced allergic asthma. Allergy. 2020;75:1347-1360 pubmed 出版商
Long Y, Tao H, Karachi A, Grippin A, Jin L, Chang Y, et al. Dysregulation of Glutamate Transport Enhances Treg Function That Promotes VEGF Blockade Resistance in Glioblastoma. Cancer Res. 2020;80:499-509 pubmed 出版商
Andersen L, Gülich A, Alteneder M, Preglej T, Orola M, Dhele N, et al. The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. Cell Rep. 2019;29:4447-4459.e6 pubmed 出版商
Gehring T, Erdmann T, Rahm M, Graß C, Flatley A, O Neill T, et al. MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells. Cell Rep. 2019;29:873-888.e10 pubmed 出版商
Tavernier S, Athanasopoulos V, Verloo P, Behrens G, Staal J, Bogaert D, et al. A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation. Nat Commun. 2019;10:4779 pubmed 出版商
Petermann F, Pekowska A, Johnson C, Jankovic D, Shih H, Jiang K, et al. The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1. Mol Cell. 2019;75:1229-1242.e5 pubmed 出版商
Lee S, Park H, Kim S, Shin S, Kim K, Park S, et al. TLR4-dependent effects of ISAg treatment on conventional T cell polarization in vivo. Anim Cells Syst (Seoul). 2019;23:184-191 pubmed 出版商
Wen S, Shim R, Ho L, Wanrooy B, Srikhanta Y, Prame Kumar K, et al. Advanced age promotes colonic dysfunction and gut-derived lung infection after stroke. Aging Cell. 2019;18:e12980 pubmed 出版商
Moffett H, Harms C, Fitzpatrick K, Tooley M, Boonyaratanakornkit J, Taylor J. B cells engineered to express pathogen-specific antibodies protect against infection. Sci Immunol. 2019;4: pubmed 出版商
Wang W, Green M, Choi J, Gijon M, Kennedy P, Johnson J, et al. CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy. Nature. 2019;569:270-274 pubmed 出版商
Zhou L, Chu C, Teng F, Bessman N, Goc J, Santosa E, et al. Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Nature. 2019;568:405-409 pubmed 出版商
Basso L, Aboushousha R, Fan C, Iftinca M, Melo H, Flynn R, et al. TRPV1 promotes opioid analgesia during inflammation. Sci Signal. 2019;12: pubmed 出版商
Cao Y, Trillo Tinoco J, Sierra R, Anadon C, Dai W, Mohamed E, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nat Commun. 2019;10:1280 pubmed 出版商
Wu J, Chen Y, Dobbs N, Sakai T, Liou J, Miner J, et al. STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death. J Exp Med. 2019;: pubmed 出版商
Pallett M, Ren H, Zhang R, Scutts S, Gonzalez L, Zhu Z, et al. Vaccinia Virus BBK E3 Ligase Adaptor A55 Targets Importin-Dependent NF-κB Activation and Inhibits CD8+ T-Cell Memory. J Virol. 2019;93: pubmed 出版商
Denton A, Innocentin S, Carr E, Bradford B, Lafouresse F, Mabbott N, et al. Type I interferon induces CXCL13 to support ectopic germinal center formation. J Exp Med. 2019;216:621-637 pubmed 出版商
Salem M, Wallace C, Velegraki M, Li A, Ansa Addo E, Metelli A, et al. GARP Dampens Cancer Immunity by Sustaining Function and Accumulation of Regulatory T Cells in the Colon. Cancer Res. 2019;: pubmed 出版商
Camilio K, Wang M, Mauseth B, Waagene S, Kvalheim G, Rekdal Ø, et al. Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model. Breast Cancer Res. 2019;21:9 pubmed 出版商
Sardar S, Kerr A, Vaartjes D, Moltved E, Karosiene E, Gupta R, et al. The oncoprotein TBX3 is controlling severity in experimental arthritis. Arthritis Res Ther. 2019;21:16 pubmed 出版商
Mulati K, Hamanishi J, Matsumura N, Chamoto K, Mise N, Abiko K, et al. VISTA expressed in tumour cells regulates T cell function. Br J Cancer. 2019;120:115-127 pubmed 出版商
Amir M, Chaudhari S, Wang R, Campbell S, Mosure S, Chopp L, et al. REV-ERBα Regulates TH17 Cell Development and Autoimmunity. Cell Rep. 2018;25:3733-3749.e8 pubmed 出版商
Du X, de Almeida P, Manieri N, de Almeida Nagata D, Wu T, Harden Bowles K, et al. CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1. Proc Natl Acad Sci U S A. 2018;115:E11731-E11740 pubmed 出版商
Szappanos D, Tschismarov R, Perlot T, Westermayer S, Fischer K, Platanitis E, et al. The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity. PLoS Pathog. 2018;14:e1007397 pubmed 出版商
Nakagawa M, RATHINAM C. Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells. Cell Rep. 2018;25:2094-2109.e4 pubmed 出版商
Lee S, Park H, Im W, Kim M, Hong S. Repeated immune activation with low-dose lipopolysaccharide attenuates the severity of Huntington's disease in R6/2 transgenic mice. Anim Cells Syst (Seoul). 2018;22:219-226 pubmed 出版商
Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed 出版商
Viaud S, Ma J, Hardy I, Hampton E, Benish B, Sherwood L, et al. Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory. Proc Natl Acad Sci U S A. 2018;115:E10898-E10906 pubmed 出版商
Ravindranathan S, Nguyen K, Kurtz S, Frazier H, Smith S, Koppolu B, et al. Tumor-derived granulocyte colony-stimulating factor diminishes efficacy of breast tumor cell vaccines. Breast Cancer Res. 2018;20:126 pubmed 出版商
Yanagisawa N, Ueshiba H, Abe Y, Kato H, Higuchi T, Yagi J. Outer Membrane Protein of Gut Commensal Microorganism Induces Autoantibody Production and Extra-Intestinal Gland Inflammation in Mice. Int J Mol Sci. 2018;19: pubmed 出版商
Lee S, Park H, Cheon J, Wu L, Van Kaer L, Hong S. iNKT Cells Suppress Pathogenic NK1.1+CD8+ T Cells in DSS-Induced Colitis. Front Immunol. 2018;9:2168 pubmed 出版商
Song M, Sandoval T, Chae C, Chopra S, Tan C, Rutkowski M, et al. IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. Nature. 2018;562:423-428 pubmed 出版商
Irons E, Lau J. Systemic ST6Gal-1 Is a Pro-survival Factor for Murine Transitional B Cells. Front Immunol. 2018;9:2150 pubmed 出版商
Masuda J, Umemura C, Yokozawa M, Yamauchi K, Seko T, Yamashita M, et al. Dietary Supplementation of Selenoneine-Containing Tuna Dark Muscle Extract Effectively Reduces Pathology of Experimental Colorectal Cancers in Mice. Nutrients. 2018;10: pubmed 出版商
Plantamura E, Dzutsev A, Chamaillard M, Djebali S, Moudombi L, Boucinha L, et al. MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype. Proc Natl Acad Sci U S A. 2018;115:10404-10409 pubmed 出版商
Tanaka S, Suto A, Iwamoto T, Kageyama T, Tamachi T, Takatori H, et al. Sox12 promotes T reg differentiation in the periphery during colitis. J Exp Med. 2018;215:2509-2519 pubmed 出版商
Knouse K, Lopez K, Bachofner M, Amon A. Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture. Cell. 2018;175:200-211.e13 pubmed 出版商
Sequeira I, Neves J, Carrero D, Peng Q, Palasz N, Liakath Ali K, et al. Immunomodulatory role of Keratin 76 in oral and gastric cancer. Nat Commun. 2018;9:3437 pubmed 出版商
Saito Reis C, Marjon K, Pascetti E, FLOREN M, Gillette J. The tetraspanin CD82 regulates bone marrow homing and engraftment of hematopoietic stem and progenitor cells. Mol Biol Cell. 2018;29:2946-2958 pubmed 出版商
Amôr N, de Oliveira C, Gasparoto T, Vilas Boas V, Perri G, Kaneno R, et al. ST2/IL-33 signaling promotes malignant development of experimental squamous cell carcinoma by decreasing NK cells cytotoxicity and modulating the intratumoral cell infiltrate. Oncotarget. 2018;9:30894-30904 pubmed 出版商
Carrero J, Benshoff N, Nalley K, Unanue E. Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice. Diabetes. 2018;67:1830-1835 pubmed 出版商
Pilat N, Mahr B, Gattringer M, Baranyi U, Wekerle T. CTLA4Ig Improves Murine iTreg Induction via TGFβ and Suppressor Function In Vitro. J Immunol Res. 2018;2018:2484825 pubmed 出版商
Nanjappa S, Mudalagiriyappa S, Fites J, Suresh M, Klein B. CBLB Constrains Inactivated Vaccine-Induced CD8+ T Cell Responses and Immunity against Lethal Fungal Pneumonia. J Immunol. 2018;201:1717-1726 pubmed 出版商
Kim S, Lee S, Park H, Lee S, Im W, Kim Y, et al. Anti-cancer activity of Angelica gigas by increasing immune response and stimulating natural killer and natural killer T cells. BMC Complement Altern Med. 2018;18:218 pubmed 出版商
Sardar S, Kanne K, Andersson A. Analysis of Polymorphisms in the Mediator Complex Subunit 13-like (Med13L) Gene in the Context of Immune Function and Development of Experimental Arthritis. Arch Immunol Ther Exp (Warsz). 2018;66:365-377 pubmed 出版商
Nakano R, Ohira M, Yano T, Imaoka Y, Tanaka Y, Ohdan H. Hepatic irradiation persistently eliminates liver resident NK cells. PLoS ONE. 2018;13:e0198904 pubmed 出版商
Lu J, Duan X, Zhao W, Wang J, Wang H, Zhou K, et al. Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology. Aging Dis. 2018;9:358-373 pubmed 出版商
Wei B, Zhang R, Zhai J, Zhu J, Yang F, Yue D, et al. Suppression of Th17 Cell Response in the Alleviation of Dextran Sulfate Sodium-Induced Colitis by Ganoderma lucidum Polysaccharides. J Immunol Res. 2018;2018:2906494 pubmed 出版商
Suryadevara C, Desai R, Abel M, Riccione K, Batich K, Shen S, et al. Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma. Oncoimmunology. 2018;7:e1434464 pubmed 出版商
Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, et al. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018;37:4941-4954 pubmed 出版商
Drobek A, Moudra A, Mueller D, Huranová M, Horková V, Pribikova M, et al. Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells. EMBO J. 2018;37: pubmed 出版商
Teruya S, Okamura T, Komai T, Inoue M, Iwasaki Y, Sumitomo S, et al. Egr2-independent, Klf1-mediated induction of PD-L1 in CD4+ T cells. Sci Rep. 2018;8:7021 pubmed 出版商
Silva M, Davoli Ferreira M, Medina T, Sesti Costa R, Silva G, Lopes C, et al. Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis. Nat Commun. 2018;9:1513 pubmed 出版商
Wu X, Gowda N, Kawasawa Y, Gowda D. A malaria protein factor induces IL-4 production by dendritic cells via PI3K-Akt-NF-κB signaling independent of MyD88/TRIF and promotes Th2 response. J Biol Chem. 2018;293:10425-10434 pubmed 出版商
Treise I, Huber E, Klein Rodewald T, Heinemeyer W, Grassmann S, Basler M, et al. Defective immuno- and thymoproteasome assembly causes severe immunodeficiency. Sci Rep. 2018;8:5975 pubmed 出版商
Powell J, Mota F, Steadman D, Soudy C, Miyauchi J, Crosby S, et al. Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells. J Med Chem. 2018;61:4135-4154 pubmed 出版商
Khong H, Volmari A, Sharma M, Dai Z, Imo C, Hailemichael Y, et al. Peptide Vaccine Formulation Controls the Duration of Antigen Presentation and Magnitude of Tumor-Specific CD8+ T Cell Response. J Immunol. 2018;200:3464-3474 pubmed 出版商
Gopinath S, Kim M, Rakib T, Wong P, Van Zandt M, Barry N, et al. Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner. Nat Microbiol. 2018;3:611-621 pubmed 出版商
Schloss J, Ali R, Racine J, Chapman H, Serreze D, DiLorenzo T. HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression. J Immunol. 2018;200:3353-3363 pubmed 出版商
Zhang J, He Z, Sen S, Wang F, Zhang Q, Sun Z. TCF-1 Inhibits IL-17 Gene Expression To Restrain Th17 Immunity in a Stage-Specific Manner. J Immunol. 2018;200:3397-3406 pubmed 出版商
Kling J, Jordan M, Pitt L, Meiners J, Thanh Tran T, Tran L, et al. Temporal Regulation of Natural Killer T Cell Interferon Gamma Responses by β-Catenin-Dependent and -Independent Wnt Signaling. Front Immunol. 2018;9:483 pubmed 出版商
Fichtner A, Karunakaran M, Starick L, Truman R, Herrmann T. The Armadillo (Dasypus novemcinctus): A Witness but Not a Functional Example for the Emergence of the Butyrophilin 3/Vγ9Vδ2 System in Placental Mammals. Front Immunol. 2018;9:265 pubmed 出版商
Chen C, Koenig A, Saison C, Dahdal S, Rigault G, Barba T, et al. CD4+ T Cell Help Is Mandatory for Naive and Memory Donor-Specific Antibody Responses: Impact of Therapeutic Immunosuppression. Front Immunol. 2018;9:275 pubmed 出版商
Oleinika K, Rosser E, Matei D, Nistala K, Bosma A, Drozdov I, et al. CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells. Nat Commun. 2018;9:684 pubmed 出版商
Mittelstadt P, Taves M, Ashwell J. Cutting Edge: De Novo Glucocorticoid Synthesis by Thymic Epithelial Cells Regulates Antigen-Specific Thymocyte Selection. J Immunol. 2018;200:1988-1994 pubmed 出版商
Davenport A, Cross R, Watson K, Liao Y, Shi W, Prince H, et al. Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity. Proc Natl Acad Sci U S A. 2018;115:E2068-E2076 pubmed 出版商
Carpier J, Zucchetti A, Bataille L, Dogniaux S, Shafaq Zadah M, Bardin S, et al. Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation. J Exp Med. 2018;215:1245-1265 pubmed 出版商
Kalim K, Yang J, Li Y, Meng Y, Zheng Y, Guo F. Reciprocal Regulation of Glycolysis-Driven Th17 Pathogenicity and Regulatory T Cell Stability by Cdc42. J Immunol. 2018;200:2313-2326 pubmed 出版商
Seki A, Rutz S. Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells. J Exp Med. 2018;215:985-997 pubmed 出版商
Risco A, Martín Serrano M, Barber D, Cuenda A. p38γ and p38δ Are Involved in T Lymphocyte Development. Front Immunol. 2018;9:65 pubmed 出版商
Morais S, Figueiredo B, Assis N, Alvarenga D, de Magalhães M, Ferreira R, et al. Schistosoma mansoni SmKI-1 serine protease inhibitor binds to elastase and impairs neutrophil function and inflammation. PLoS Pathog. 2018;14:e1006870 pubmed 出版商
Li Z, Zhang S, Wan Y, Cai M, Wang W, Zhu Y, et al. MicroRNA-146a Overexpression Impairs the Positive Selection during T Cell Development. Front Immunol. 2017;8:2006 pubmed 出版商
Zhang Q, Lee W, Kang J, Kim L, Kim Y. Integrin CD11b negatively regulates Mincle-induced signaling via the Lyn-SIRPα-SHP1 complex. Exp Mol Med. 2018;50:e439 pubmed 出版商
Cortes J, Ambesi Impiombato A, Couronné L, Quinn S, Kim C, da Silva Almeida A, et al. RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis. Cancer Cell. 2018;33:259-273.e7 pubmed 出版商
Ranganathan P, Shanmugam A, Swafford D, Suryawanshi A, Bhattacharjee P, Hussein M, et al. GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis. J Immunol. 2018;200:1781-1789 pubmed 出版商
Linehan J, Harrison O, Han S, Byrd A, Vujkovic Cvijin I, Villarino A, et al. Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair. Cell. 2018;172:784-796.e18 pubmed 出版商
Alam M, Gaida M, Debnath S, Tagad H, Miller Jenkins L, Appella E, et al. Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation. PLoS Biol. 2018;16:e2004111 pubmed 出版商
Mustafa D, Pedrosa R, Smid M, van der Weiden M, de Weerd V, Nigg A, et al. T lymphocytes facilitate brain metastasis of breast cancer by inducing Guanylate-Binding Protein 1 expression. Acta Neuropathol. 2018;135:581-599 pubmed 出版商
Reynolds C, Suleyman O, Ortega Prieto A, Skelton J, Bonnesoeur P, Blohm A, et al. T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses. Sci Rep. 2018;8:672 pubmed 出版商
Chockley P, Chen J, Chen G, Beer D, Standiford T, Keshamouni V. Epithelial-mesenchymal transition leads to NK cell-mediated metastasis-specific immunosurveillance in lung cancer. J Clin Invest. 2018;128:1384-1396 pubmed 出版商
Sprouse M, Shevchenko I, Scavuzzo M, Joseph F, Lee T, Blum S, et al. Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity. J Immunol. 2018;200:909-914 pubmed 出版商
Maltby S, Lochrin A, Bartlett B, Tay H, Weaver J, Poulton I, et al. Osteoblasts Are Rapidly Ablated by Virus-Induced Systemic Inflammation following Lymphocytic Choriomeningitis Virus or Pneumonia Virus of Mice Infection in Mice. J Immunol. 2018;200:632-642 pubmed 出版商
Hermida M, Malta R, de S Santos M, dos Santos W. Selecting the right gate to identify relevant cells for your assay: a study of thioglycollate-elicited peritoneal exudate cells in mice. BMC Res Notes. 2017;10:695 pubmed 出版商
Wilck N, Matus M, Kearney S, Olesen S, Forslund K, Bartolomaeus H, et al. Salt-responsive gut commensal modulates TH17 axis and disease. Nature. 2017;: pubmed 出版商
Veselits M, Tanaka A, Chen Y, Hamel K, Mandal M, Kandasamy M, et al. Ig? ubiquitination activates PI3K signals required for endosomal sorting. J Exp Med. 2017;214:3775-3790 pubmed 出版商
Quatrini L, Wieduwild E, Guia S, Bernat C, Glaichenhaus N, Vivier E, et al. Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells. J Exp Med. 2017;214:3531-3541 pubmed 出版商
Jang J, Li J, Gambini L, Batugedara H, Sati S, Lazar M, et al. Human resistin protects against endotoxic shock by blocking LPS-TLR4 interaction. Proc Natl Acad Sci U S A. 2017;114:E10399-E10408 pubmed 出版商
Bartemes K, Chen C, Iijima K, Drake L, Kita H. IL-33-Responsive Group 2 Innate Lymphoid Cells Are Regulated by Female Sex Hormones in the Uterus. J Immunol. 2018;200:229-236 pubmed 出版商
Wasiuk A, Testa J, Weidlick J, Sisson C, Vitale L, Widger J, et al. CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy. J Immunol. 2017;199:4110-4123 pubmed 出版商
Pollard K, Escalante G, Huang H, Haraldsson K, Hultman P, Christy J, et al. Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN. J Immunol. 2017;199:3739-3747 pubmed 出版商
Roussey J, Viglianti S, Teitz Tennenbaum S, Olszewski M, Osterholzer J. Anti-PD-1 Antibody Treatment Promotes Clearance of Persistent Cryptococcal Lung Infection in Mice. J Immunol. 2017;199:3535-3546 pubmed 出版商
Patel S, Yokoyama W. CD8+ T Cells Prevent Lethality from Neonatal Murine Roseolovirus Infection. J Immunol. 2017;199:3212-3221 pubmed 出版商
Isoda T, Moore A, He Z, Chandra V, Aida M, Denholtz M, et al. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 2017;171:103-119.e18 pubmed 出版商
Burns K, Thomas S, Hamilton K, Young S, Cook D, Korach K. Early Endometriosis in Females Is Directed by Immune-Mediated Estrogen Receptor α and IL-6 Cross-Talk. Endocrinology. 2018;159:103-118 pubmed 出版商
Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, et al. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32:377-391.e9 pubmed 出版商
Barik S, Miller M, Cattin Roy A, Ukah T, Chen W, Zaghouani H. IL-4/IL-13 Signaling Inhibits the Potential of Early Thymic Progenitors To Commit to the T Cell Lineage. J Immunol. 2017;199:2767-2776 pubmed 出版商
Blanchfield L, Sabatino J, Lawrence L, Evavold B. NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease. J Immunol. 2017;199:2680-2691 pubmed 出版商
Madireddi S, Eun S, Mehta A, Birta A, Zajonc D, Niki T, et al. Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9. J Immunol. 2017;199:2721-2728 pubmed 出版商
Ingram J, Blomberg O, Sockolosky J, Ali L, Schmidt F, Pishesha N, et al. Localized CD47 blockade enhances immunotherapy for murine melanoma. Proc Natl Acad Sci U S A. 2017;114:10184-10189 pubmed 出版商
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed 出版商
Bucsek M, Qiao G, MacDonald C, Giridharan T, Evans L, Niedzwecki B, et al. β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy. Cancer Res. 2017;77:5639-5651 pubmed 出版商
Kanemaru H, Yamane F, Fukushima K, Matsuki T, Kawasaki T, Ebina I, et al. Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages. Proc Natl Acad Sci U S A. 2017;114:E7331-E7340 pubmed 出版商
He L, Zhou S, Qi Q, Chi Y, Zhu J, Xu Z, et al. The regulation of regulation: interleukin-10 increases CD4+ CD25+ regulatory T cells but impairs their immunosuppressive activity in murine models with schistosomiasis japonica or asthma. Immunology. 2018;153:84-96 pubmed 出版商
Wiede F, Dudakov J, Lu K, Dodd G, Butt T, Godfrey D, et al. PTPN2 regulates T cell lineage commitment and αβ versus γδ specification. J Exp Med. 2017;214:2733-2758 pubmed 出版商
Li H, Tong J, Zhu S, Batista P, Duffy E, Zhao J, et al. m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways. Nature. 2017;548:338-342 pubmed 出版商
Shi X, Lin Y, Gao B, Zhang P. Impairment of Hematopoietic Precursor Cell Activation during the Granulopoietic Response to Bacteremia in Mice with Chronic-Plus-Binge Alcohol Administration. Infect Immun. 2017;85: pubmed 出版商
Sugita S, Shimizu J, Makabe K, Keino H, Watanabe T, Takahashi M. Inhibition of T cell-mediated inflammation in uveitis by a novel anti-CD3 antibody. Arthritis Res Ther. 2017;19:176 pubmed 出版商
Liao X, Ren J, Reihl A, Pirapakaran T, Sreekumar B, Cecere T, et al. Renal-infiltrating CD11c+ cells are pathogenic in murine lupus nephritis through promoting CD4+ T cell responses. Clin Exp Immunol. 2017;190:187-200 pubmed 出版商
Wu X, Dayanand K, Thylur R, Norbury C, Gowda D. Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes. J Biol Chem. 2017;292:13615-13634 pubmed 出版商
Kim D, Seo S, Zeng M, Kim W, Kamada N, Inohara N, et al. Mesenchymal Cell-Specific MyD88 Signaling Promotes Systemic Dissemination of Salmonella Typhimurium via Inflammatory Monocytes. J Immunol. 2017;199:1362-1371 pubmed 出版商
Lee S, Park H, Suh Y, Yoon E, Kim J, Jang W, et al. Inhibition of acute lethal pulmonary inflammation by the IDO-AhR pathway. Proc Natl Acad Sci U S A. 2017;114:E5881-E5890 pubmed 出版商
Karim A, Reba S, Li Q, Boom W, Rojas R. Toll like Receptor 2 engagement on CD4+ T cells promotes TH9 differentiation and function. Eur J Immunol. 2017;47:1513-1524 pubmed 出版商
Dudakov J, Mertelsmann A, O Connor M, Jenq R, Velardi E, Young L, et al. Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease. Blood. 2017;130:933-942 pubmed 出版商
Zhao Q, Harbour S, Kolde R, Latorre I, Tun H, Schoeb T, et al. Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota. J Immunol. 2017;199:312-322 pubmed 出版商
Klocke K, Holmdahl R, Wing K. CTLA-4 expressed by FOXP3+ regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis. Immunology. 2017;152:125-137 pubmed 出版商
Burton O, Tamayo J, Stranks A, Koleoglou K, Oettgen H. Allergen-specific IgG antibody signaling through FcγRIIb promotes food tolerance. J Allergy Clin Immunol. 2018;141:189-201.e3 pubmed 出版商
Ratiu J, Racine J, Hasham M, Wang Q, Branca J, Chapman H, et al. Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes. J Immunol. 2017;198:4255-4267 pubmed 出版商
Ripamonti C, Bishop L, Kovacs J. Pulmonary Interleukin-17-Positive Lymphocytes Increase during Pneumocystis murina Infection but Are Not Required for Clearance of Pneumocystis. Infect Immun. 2017;85: pubmed 出版商
de Oliveira M, Oliveira L, Lira A, Sgnotto F, Duarte A, Sato M, et al. Preconception allergen sensitization can induce B10 cells in offspring: a potential main role for maternal IgG. Allergy Asthma Clin Immunol. 2017;13:22 pubmed 出版商
Fenske R, Cadena M, Harenda Q, Wienkes H, Carbajal K, Schaid M, et al. The Inhibitory G Protein ?-Subunit, G?z, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice. Endocrinology. 2017;158:1645-1658 pubmed 出版商
Thylur R, Wu X, Gowda N, Punnath K, Neelgund S, Febbraio M, et al. CD36 receptor regulates malaria-induced immune responses primarily at early blood stage infection contributing to parasitemia control and resistance to mortality. J Biol Chem. 2017;292:9394-9408 pubmed 出版商
Claser C, de Souza J, Thorburn S, Grau G, Riley E, Renia L, et al. Host Resistance to Plasmodium-Induced Acute Immune Pathology Is Regulated by Interleukin-10 Receptor Signaling. Infect Immun. 2017;85: pubmed 出版商
Bi X, Li F, Liu S, Jin Y, Zhang X, Yang T, et al. ?-3 polyunsaturated fatty acids ameliorate type 1 diabetes and autoimmunity. J Clin Invest. 2017;127:1757-1771 pubmed 出版商
Cunin P, Penke L, Thon J, Monach P, Jones T, Chang M, et al. Megakaryocytes compensate for Kit insufficiency in murine arthritis. J Clin Invest. 2017;127:1714-1724 pubmed 出版商
Gomez Lopez N, Romero R, Arenas Hernandez M, Schwenkel G, St Louis D, Hassan S, et al. In vivo activation of invariant natural killer T cells induces systemic and local alterations in T-cell subsets prior to preterm birth. Clin Exp Immunol. 2017;189:211-225 pubmed 出版商
Forsberg M, Ciecko A, Bednar K, Itoh A, Kachapati K, Ridgway W, et al. CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice. J Immunol. 2017;198:3857-3868 pubmed 出版商
Cheemarla N, Banos Lara M, Naidu S, Guerrero Plata A. Neutrophils regulate the lung inflammatory response via ?? T cell infiltration in an experimental mouse model of human metapneumovirus infection. J Leukoc Biol. 2017;101:1383-1392 pubmed 出版商
Chung J, Ebens C, Perkey E, Radojcic V, Koch U, Scarpellino L, et al. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest. 2017;127:1574-1588 pubmed 出版商
Bartee M, Dunlap K, Bartee E. Tumor-Localized Secretion of Soluble PD1 Enhances Oncolytic Virotherapy. Cancer Res. 2017;77:2952-2963 pubmed 出版商
Ansa Addo E, Zhang Y, Yang Y, Hussey G, Howley B, Salem M, et al. Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-β signaling. J Clin Invest. 2017;127:1321-1337 pubmed 出版商
Brandstadter J, Chen H, Jiang S, Huang X, Yang Y. IL-18-dependent NKG2D ligand upregulation on accessory cells is mediated by the PI3K/GSK-3 pathway. J Leukoc Biol. 2017;101:1317-1323 pubmed 出版商
Shaw M, Gao Z, McElhinney K, Thornton S, Flick M, Lane A, et al. Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease. J Neurosci. 2017;37:3776-3788 pubmed 出版商
Wang H, Qian L, Zhao Y, Mengarelli J, Adrianto I, Montgomery C, et al. Downregulation of E Protein Activity Augments an ILC2 Differentiation Program in the Thymus. J Immunol. 2017;198:3149-3156 pubmed 出版商
Stacey M, Clare S, Clement M, Marsden M, Abdul Karim J, Kane L, et al. The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis. J Clin Invest. 2017;127:1463-1474 pubmed 出版商
Zhang H, Qi Y, Yuan Y, Cai L, Xu H, Zhang L, et al. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation. Sci Rep. 2017;7:41887 pubmed 出版商
Beavis P, Henderson M, Giuffrida L, Mills J, Sek K, Cross R, et al. Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy. J Clin Invest. 2017;127:929-941 pubmed 出版商
Pardi N, Hogan M, Pelc R, Muramatsu H, Andersen H, Demaso C, et al. Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination. Nature. 2017;543:248-251 pubmed 出版商
Guan J, Yang S, Gonzalez F, Yin Y, Shastri N. Antigen Processing in the Endoplasmic Reticulum Is Monitored by Semi-Invariant αβ TCRs Specific for a Conserved Peptide-Qa-1b MHC Class Ib Ligand. J Immunol. 2017;198:2017-2027 pubmed 出版商
Freund P, Kerenyi M, Hager M, Wagner T, Wingelhofer B, Pham H, et al. O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies. Leukemia. 2017;31:2132-2142 pubmed 出版商
Rowe A, Yun H, Hendricks R. Exposure Stress Induces Reversible Corneal Graft Opacity in Recipients With Herpes Simplex Virus-1 Infections. Invest Ophthalmol Vis Sci. 2017;58:35-41 pubmed 出版商
Ehrlich A, Fernández O, Rodriguez Pinto D, Castilho T, Corral Caridad M, Goldsmith Pestana K, et al. Local Delivery of the Toll-Like Receptor 9 Ligand CpG Downregulates Host Immune and Inflammatory Responses, Ameliorating Established Leishmania (Viannia) panamensis Chronic Infection. Infect Immun. 2017;85: pubmed 出版商
Phan T, Jaruga B, Pingle S, Bandyopadhyay B, Ahern G. Intrinsic Photosensitivity Enhances Motility of T Lymphocytes. Sci Rep. 2016;6:39479 pubmed 出版商
Liu W, Yu W, Zhang J, Chan R, Loh M, Zhang Z, et al. Inhibition of the Gab2/PI3K/mTOR signaling ameliorates myeloid malignancy caused by Ptpn11 (Shp2) gain-of-function mutations. Leukemia. 2017;31:1415-1422 pubmed 出版商
Ishikawa E, Kosako H, Yasuda T, Ohmuraya M, Araki K, Kurosaki T, et al. Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1. Nat Commun. 2016;7:12756 pubmed 出版商
Alberdi M, Iglesias M, Tejedor S, Merino R, Lopez Rodriguez C, Aramburu J. Context-dependent regulation of Th17-associated genes and IFN? expression by the transcription factor NFAT5. Immunol Cell Biol. 2017;95:56-67 pubmed 出版商
De Grove K, Provoost S, Hendriks R, McKenzie A, Seys L, Kumar S, et al. Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses. J Allergy Clin Immunol. 2017;139:246-257.e4 pubmed 出版商
Rabacal W, Pabbisetty S, Hoek K, Cendron D, Guo Y, Maseda D, et al. Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival. Proc Natl Acad Sci U S A. 2016;113:5370-5 pubmed 出版商
Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed 出版商
Barsoumian H, Yolcu E, Shirwan H. 4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4+CD25+FoxP3+ T Regulatory Cell Suppression. PLoS ONE. 2016;11:e0153088 pubmed 出版商
Whibley N, Tritto E, Traggiai E, Kolbinger F, Moulin P, Brees D, et al. Antibody blockade of IL-17 family cytokines in immunity to acute murine oral mucosal candidiasis. J Leukoc Biol. 2016;99:1153-64 pubmed 出版商
Vivar O, Masi G, Carpier J, Magalhaes J, Galgano D, Pazour G, et al. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113:386-91 pubmed 出版商
Brennan T, Lin L, Brandstadter J, Rendell V, Dredge K, Huang X, et al. Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation. J Clin Invest. 2016;126:207-19 pubmed 出版商
Arnold J, Murera D, Arbogast F, Fauny J, Muller S, Gros F. Autophagy is dispensable for B-cell development but essential for humoral autoimmune responses. Cell Death Differ. 2016;23:853-64 pubmed 出版商
Oh Y, Park H, Shin J, Lee J, Park H, Kho D, et al. Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2. Nat Commun. 2015;6:8698 pubmed 出版商
Sánchez González B, García Vázquez F, Farfán Morales J, Jiménez Zamudio L. Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse. Mediators Inflamm. 2015;2015:313140 pubmed 出版商
Mikucki M, Fisher D, Matsuzaki J, Skitzki J, Gaulin N, Muhitch J, et al. Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints. Nat Commun. 2015;6:7458 pubmed 出版商
Charmsaz S, Beckett K, Smith F, Bruedigam C, Moore A, Al Ejeh F, et al. EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia. PLoS ONE. 2015;10:e0130692 pubmed 出版商
Teo T, Her Z, Tan J, Lum F, Lee W, Chan Y, et al. Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology. J Virol. 2015;89:7955-69 pubmed 出版商
Niebling J, E Rünker A, Schallenberg S, Kretschmer K, Kempermann G. Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms. F1000Res. 2014;3:169 pubmed 出版商
Liu E, McDaniel K, Case S, Yu L, Gerhartz B, Ostermann N, et al. Exploring T cell reactivity to gliadin in young children with newly diagnosed celiac disease. Autoimmune Dis. 2014;2014:927190 pubmed 出版商
Diaz de Durana Y, Lau J, Knee D, Filippi C, Londei M, McNamara P, et al. IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes. PLoS ONE. 2013;8:e78483 pubmed 出版商
Stern A, Wold A, Ostman S. Neonatal mucosal immune stimulation by microbial superantigen improves the tolerogenic capacity of CD103(+) dendritic cells. PLoS ONE. 2013;8:e75594 pubmed 出版商
Vink P, Smout W, Driessen Engels L, de Bruin A, Delsing D, Krajnc Franken M, et al. In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation. PLoS ONE. 2013;8:e57348 pubmed 出版商
van Lierop M, Alkema W, Laskewitz A, Dijkema R, van der Maaden H, Smit M, et al. Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index. PLoS ONE. 2012;7:e48385 pubmed 出版商
Chouker A, Ohta A, Martignoni A, Lukashev D, Zacharia L, Jackson E, et al. In vivo hypoxic preconditioning protects from warm liver ischemia-reperfusion injury through the adenosine A2B receptor. Transplantation. 2012;94:894-902 pubmed 出版商
Sawant D, Sehra S, Nguyen E, Jadhav R, Englert K, Shinnakasu R, et al. Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. J Immunol. 2012;189:4759-69 pubmed 出版商
Rush C, Nyara M, Moxon J, Trollope A, Cullen B, Golledge J. Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysm. BMC Genomics. 2009;10:298 pubmed 出版商
Carlson T, Kroenke M, Rao P, Lane T, Segal B. The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease. J Exp Med. 2008;205:811-23 pubmed 出版商
Evans A, Moser J, Krug L, Pozharskaya V, Mora A, Speck S. A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology. J Exp Med. 2008;205:669-84 pubmed 出版商
Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, et al. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med. 2007;204:2803-12 pubmed
Alcázar I, Marqués M, Kumar A, Hirsch E, Wymann M, Carrera A, et al. Phosphoinositide 3-kinase gamma participates in T cell receptor-induced T cell activation. J Exp Med. 2007;204:2977-87 pubmed
Onoyama I, Tsunematsu R, Matsumoto A, Kimura T, de Alboran I, Nakayama K, et al. Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis. J Exp Med. 2007;204:2875-88 pubmed
Iwakoshi N, Pypaert M, Glimcher L. The transcription factor XBP-1 is essential for the development and survival of dendritic cells. J Exp Med. 2007;204:2267-75 pubmed
Scott Browne J, Shafiani S, Tucker Heard G, Ishida Tsubota K, Fontenot J, Rudensky A, et al. Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis. J Exp Med. 2007;204:2159-69 pubmed
Narni Mancinelli E, Campisi L, Bassand D, Cazareth J, Gounon P, Glaichenhaus N, et al. Memory CD8+ T cells mediate antibacterial immunity via CCL3 activation of TNF/ROI+ phagocytes. J Exp Med. 2007;204:2075-87 pubmed
Sun C, Hall J, Blank R, Bouladoux N, Oukka M, Mora J, et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med. 2007;204:1775-85 pubmed
Coombes J, Siddiqui K, Arancibia Cárcamo C, Hall J, Sun C, Belkaid Y, et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med. 2007;204:1757-64 pubmed
Yuan Q, Bromley S, Means T, Jones K, Hayashi F, Bhan A, et al. CCR4-dependent regulatory T cell function in inflammatory bowel disease. J Exp Med. 2007;204:1327-34 pubmed
Rossi S, Kim M, Leibbrandt A, Parnell S, Jenkinson W, Glanville S, et al. RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J Exp Med. 2007;204:1267-72 pubmed
Humphreys I, De Trez C, Kinkade A, Benedict C, Croft M, Ware C. Cytomegalovirus exploits IL-10-mediated immune regulation in the salivary glands. J Exp Med. 2007;204:1217-25 pubmed
Waisman A, Kraus M, Seagal J, Ghosh S, Melamed D, Song J, et al. IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta. J Exp Med. 2007;204:747-58 pubmed
Purton J, Tan J, Rubinstein M, Kim D, Sprent J, Surh C. Antiviral CD4+ memory T cells are IL-15 dependent. J Exp Med. 2007;204:951-61 pubmed
Henderson W, Chi E, Bollinger J, Tien Y, Ye X, Castelli L, et al. Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model. J Exp Med. 2007;204:865-77 pubmed
Loeser S, Loser K, Bijker M, Rangachari M, van der Burg S, Wada T, et al. Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells. J Exp Med. 2007;204:879-91 pubmed
Schleicher U, Liese J, Knippertz I, Kurzmann C, Hesse A, Heit A, et al. NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs. J Exp Med. 2007;204:893-906 pubmed
Schneider M, Meingassner J, Lipp M, Moore H, Rot A. CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells. J Exp Med. 2007;204:735-45 pubmed
Dunn S, Ousman S, Sobel R, Zuniga L, Baranzini S, Youssef S, et al. Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. J Exp Med. 2007;204:321-30 pubmed
Hirota K, Hashimoto M, Yoshitomi H, Tanaka S, Nomura T, Yamaguchi T, et al. T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis. J Exp Med. 2007;204:41-7 pubmed
Schnyder Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, Quesniaux V, et al. Interleukin-17 is a negative regulator of established allergic asthma. J Exp Med. 2006;203:2715-25 pubmed
Das G, Das J, Eynott P, Zhang Y, Bothwell A, Van Kaer L, et al. Pivotal roles of CD8+ T cells restricted by MHC class I-like molecules in autoimmune diseases. J Exp Med. 2006;203:2603-11 pubmed
Yurchenko E, Tritt M, Hay V, Shevach E, Belkaid Y, Piccirillo C. CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence. J Exp Med. 2006;203:2451-60 pubmed
Friend L, Shah D, Deppong C, Lin J, Bricker T, Juehne T, et al. A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant. J Exp Med. 2006;203:2121-33 pubmed
Umemoto E, Tanaka T, Kanda H, Jin S, Tohya K, Otani K, et al. Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow. J Exp Med. 2006;203:1603-14 pubmed
Fallon P, Ballantyne S, Mangan N, Barlow J, Dasvarma A, Hewett D, et al. Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med. 2006;203:1105-16 pubmed
Kjer Nielsen L, Borg N, Pellicci D, Beddoe T, Kostenko L, Clements C, et al. A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition. J Exp Med. 2006;203:661-73 pubmed
Boscardin S, Hafalla J, Masilamani R, Kamphorst A, Zebroski H, Rai U, et al. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. J Exp Med. 2006;203:599-606 pubmed
Bajenoff M, Breart B, Huang A, Qi H, Cazareth J, Braud V, et al. Natural killer cell behavior in lymph nodes revealed by static and real-time imaging. J Exp Med. 2006;203:619-31 pubmed
Olson T, Reuter B, Scott K, Morris M, Wang X, Hancock L, et al. The primary defect in experimental ileitis originates from a nonhematopoietic source. J Exp Med. 2006;203:541-52 pubmed
Dunn S, Youssef S, Goldstein M, Prod homme T, Weber M, Zamvil S, et al. Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin. J Exp Med. 2006;203:401-12 pubmed
Marti F, Garcia G, Lapinski P, Macgregor J, King P. Essential role of the T cell-specific adapter protein in the activation of LCK in peripheral T cells. J Exp Med. 2006;203:281-7 pubmed
Hayes S, Love P. Stoichiometry of the murine gammadelta T cell receptor. J Exp Med. 2006;203:47-52 pubmed
Zhong F, Davis M, McColl K, Distelhorst C. Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation. J Cell Biol. 2006;172:127-37 pubmed
Bafica A, Scanga C, Feng C, Leifer C, Cheever A, Sher A. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J Exp Med. 2005;202:1715-24 pubmed
Chen S, Kawashima H, Lowe J, Lanier L, Fukuda M. Suppression of tumor formation in lymph nodes by L-selectin-mediated natural killer cell recruitment. J Exp Med. 2005;202:1679-89 pubmed
Jiang H, Pan F, Erickson L, Jang M, Sanui T, Kunisaki Y, et al. Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection. J Exp Med. 2005;202:1121-30 pubmed
Annacker O, Coombes J, Malmstrom V, Uhlig H, Bourne T, Johansson Lindbom B, et al. Essential role for CD103 in the T cell-mediated regulation of experimental colitis. J Exp Med. 2005;202:1051-61 pubmed
Yasunami Y, Kojo S, Kitamura H, Toyofuku A, Satoh M, Nakano M, et al. Valpha14 NK T cell-triggered IFN-gamma production by Gr-1+CD11b+ cells mediates early graft loss of syngeneic transplanted islets. J Exp Med. 2005;202:913-8 pubmed
Yoneyama H, Matsuno K, Toda E, Nishiwaki T, Matsuo N, Nakano A, et al. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J Exp Med. 2005;202:425-35 pubmed
Muljo S, Ansel K, Kanellopoulou C, Livingston D, Rao A, Rajewsky K. Aberrant T cell differentiation in the absence of Dicer. J Exp Med. 2005;202:261-9 pubmed
Benz C, Bleul C. A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision. J Exp Med. 2005;202:21-31 pubmed
Semmrich M, Smith A, Feterowski C, Beer S, Engelhardt B, Busch D, et al. Importance of integrin LFA-1 deactivation for the generation of immune responses. J Exp Med. 2005;201:1987-98 pubmed
Shin T, Yoshimura K, Shin T, Crafton E, Tsuchiya H, Housseau F, et al. In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. J Exp Med. 2005;201:1531-41 pubmed
van Rijt L, Jung S, Kleinjan A, Vos N, Willart M, Duez C, et al. In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma. J Exp Med. 2005;201:981-91 pubmed
Setoguchi R, Hori S, Takahashi T, Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med. 2005;201:723-35 pubmed
Liu J, Miwa T, Hilliard B, Chen Y, Lambris J, Wells A, et al. The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo. J Exp Med. 2005;201:567-77 pubmed
Roers A, Siewe L, Strittmatter E, Deckert M, Schluter D, Stenzel W, et al. T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. J Exp Med. 2004;200:1289-97 pubmed
Amprey J, Im J, Turco S, Murray H, Illarionov P, Besra G, et al. A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan. J Exp Med. 2004;200:895-904 pubmed
Ling K, Ottersbach K, van Hamburg J, Oziemlak A, Tsai F, Orkin S, et al. GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells. J Exp Med. 2004;200:871-82 pubmed
Tong J, Allenspach E, Takahashi S, Mody P, Park C, Burkhardt J, et al. CD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanism. J Exp Med. 2004;199:1277-83 pubmed
Shiratori I, Ogasawara K, Saito T, Lanier L, Arase H. Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor. J Exp Med. 2004;199:525-33 pubmed
Chen W, Jin W, Hardegen N, Lei K, Li L, Marinos N, et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med. 2003;198:1875-86 pubmed
Schmieg J, Yang G, Franck R, Tsuji M. Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-Galactosylceramide. J Exp Med. 2003;198:1631-41 pubmed
Fujikawa K, Miletic A, Alt F, Faccio R, Brown T, Hoog J, et al. Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells. J Exp Med. 2003;198:1595-608 pubmed
Blaeser F, Bryce P, Ho N, Raman V, Dedeoglu F, Donaldson D, et al. Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation. J Exp Med. 2003;198:1189-200 pubmed
Sangster M, Riberdy J, Gonzalez M, Topham D, Baumgarth N, Doherty P. An early CD4+ T cell-dependent immunoglobulin A response to influenza infection in the absence of key cognate T-B interactions. J Exp Med. 2003;198:1011-21 pubmed
Johansson Lindbom B, Svensson M, Wurbel M, Malissen B, Marquez G, Agace W. Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant. J Exp Med. 2003;198:963-9 pubmed
Drappa J, Kamen L, Chan E, Georgiev M, Ashany D, Marti F, et al. Impaired T cell death and lupus-like autoimmunity in T cell-specific adapter protein-deficient mice. J Exp Med. 2003;198:809-21 pubmed
Boehm T, Scheu S, Pfeffer K, Bleul C. Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. J Exp Med. 2003;198:757-69 pubmed
Prass K, Meisel C, Höflich C, Braun J, Halle E, Wolf T, et al. Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med. 2003;198:725-36 pubmed
Cretney E, Uldrich A, Berzins S, Strasser A, Godfrey D, Smyth M. Normal thymocyte negative selection in TRAIL-deficient mice. J Exp Med. 2003;198:491-6 pubmed
Filippi C, Hugues S, Cazareth J, Julia V, Glaichenhaus N, Ugolini S. CD4+ T cell polarization in mice is modulated by strain-specific major histocompatibility complex-independent differences within dendritic cells. J Exp Med. 2003;198:201-9 pubmed
Komine O, Hayashi K, Natsume W, Watanabe T, Seki Y, Seki N, et al. The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression. J Exp Med. 2003;198:51-61 pubmed
Chen C, Seguin Devaux C, Burke N, Oriss T, Watkins S, Clipstone N, et al. Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation. J Exp Med. 2003;197:1689-99 pubmed
Pfeifhofer C, Kofler K, Gruber T, Tabrizi N, Lutz C, Maly K, et al. Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells. J Exp Med. 2003;197:1525-35 pubmed
Esplugues E, Sancho D, Vega Ramos J, Martinez C, Syrbe U, Hamann A, et al. Enhanced antitumor immunity in mice deficient in CD69. J Exp Med. 2003;197:1093-106 pubmed
Wang S, Bajorath J, Flies D, Dong H, Honjo T, Chen L. Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J Exp Med. 2003;197:1083-91 pubmed
Chun T, Page M, Gapin L, Matsuda J, Xu H, Nguyen H, et al. CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells. J Exp Med. 2003;197:907-18 pubmed
Savinov A, Wong F, Stonebraker A, Chervonsky A. Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells. J Exp Med. 2003;197:643-56 pubmed
Thien C, Scaife R, Papadimitriou J, Murphy M, Bowtell D, Langdon W. A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase. J Exp Med. 2003;197:503-13 pubmed
Caramalho I, Lopes Carvalho T, Ostler D, Zelenay S, Haury M, Demengeot J. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med. 2003;197:403-11 pubmed
Hayes S, Laky K, El Khoury D, Kappes D, Fowlkes B, Love P. Activation-induced modification in the CD3 complex of the gammadelta T cell receptor. J Exp Med. 2002;196:1355-61 pubmed
Liu Q, Fleischmann B, Hondowicz B, Maier C, Turka L, Yui K, et al. Modulation of Kv channel expression and function by TCR and costimulatory signals during peripheral CD4(+) lymphocyte differentiation. J Exp Med. 2002;196:897-909 pubmed
Tarbell K, Lee M, Ranheim E, Chao C, Sanna M, Kim S, et al. CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer. J Exp Med. 2002;196:481-92 pubmed
Hoffmann P, Ermann J, Edinger M, Fathman C, Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med. 2002;196:389-99 pubmed
Ye Q, Press B, Kissler S, Yang X, Lu L, Bassing C, et al. T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice. J Exp Med. 2002;196:87-95 pubmed
Diehl S, Chow C, Weiss L, Palmetshofer A, Twardzik T, Rounds L, et al. Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation. J Exp Med. 2002;196:39-49 pubmed
Cusson N, Oikemus S, Kilpatrick E, Cunningham L, Kelliher M. The death domain kinase RIP protects thymocytes from tumor necrosis factor receptor type 2-induced cell death. J Exp Med. 2002;196:15-26 pubmed
Yoneyama H, Narumi S, Zhang Y, Murai M, Baggiolini M, Lanzavecchia A, et al. Pivotal role of dendritic cell-derived CXCL10 in the retention of T helper cell 1 lymphocytes in secondary lymph nodes. J Exp Med. 2002;195:1257-66 pubmed
Moron G, Rueda P, Casal I, Leclerc C. CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules. J Exp Med. 2002;195:1233-45 pubmed
Pellicci D, Hammond K, Uldrich A, Baxter A, Smyth M, Godfrey D. A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage. J Exp Med. 2002;195:835-44 pubmed
Bowman E, Kuklin N, Youngman K, Lazarus N, Kunkel E, Pan J, et al. The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells. J Exp Med. 2002;195:269-75 pubmed
Alcamo E, Hacohen N, Schulte L, Rennert P, Hynes R, Baltimore D. Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs. J Exp Med. 2002;195:233-44 pubmed
Takaki S, Morita H, Tezuka Y, Takatsu K. Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk. J Exp Med. 2002;195:151-60 pubmed
Schneider P, Takatsuka H, Wilson A, Mackay F, Tardivel A, Lens S, et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med. 2001;194:1691-7 pubmed
Ibe S, Qin Z, Schuler T, Preiss S, Blankenstein T. Tumor rejection by disturbing tumor stroma cell interactions. J Exp Med. 2001;194:1549-59 pubmed
Nakano H, Yanagita M, Gunn M. CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J Exp Med. 2001;194:1171-8 pubmed
Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M, et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med. 2001;194:769-79 pubmed
Sasaki T, Wada T, Kishimoto H, Irie Sasaki J, Matsumoto G, Goto T, et al. The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells. J Exp Med. 2001;194:757-68 pubmed
Gibbons D, Douglas N, Barber D, Liu Q, Sullo R, Geng L, et al. The biological activity of natural and mutant pTalpha alleles. J Exp Med. 2001;194:695-703 pubmed
Almeida A, Borghans J, Freitas A. T cell homeostasis: thymus regeneration and peripheral T cell restoration in mice with a reduced fraction of competent precursors. J Exp Med. 2001;194:591-9 pubmed
Ruiz Vela A, Serrano F, Gonzalez M, Abad J, Bernad A, Maki M, et al. Transplanted long-term cultured pre-BI cells expressing calpastatin are resistant to B cell receptor-induced apoptosis. J Exp Med. 2001;194:247-54 pubmed
Marti F, Post N, Chan E, King P. A transcription function for the T cell-specific adapter (TSAd) protein in T cells: critical role of the TSAd Src homology 2 domain. J Exp Med. 2001;193:1425-30 pubmed
Agata Y, Katakai T, Ye S, Sugai M, Gonda H, Honjo T, et al. Histone acetylation determines the developmentally regulated accessibility for T cell receptor gamma gene recombination. J Exp Med. 2001;193:873-80 pubmed
Schmedt C, Tarakhovsky A. Autonomous maturation of alpha/beta T lineage cells in the absence of COOH-terminal Src kinase (Csk). J Exp Med. 2001;193:815-26 pubmed
Van Laethem F, Baus E, Smyth L, Andris F, Bex F, Urbain J, et al. Glucocorticoids attenuate T cell receptor signaling. J Exp Med. 2001;193:803-14 pubmed
Leuker C, Labow M, Muller W, Wagner N. Neonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune response. J Exp Med. 2001;193:755-68 pubmed
Fehniger T, Suzuki K, Ponnappan A, VanDeusen J, Cooper M, Florea S, et al. Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells. J Exp Med. 2001;193:219-31 pubmed
Yoneyama H, Matsuno K, Zhang Y, Murai M, Itakura M, Ishikawa S, et al. Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease. J Exp Med. 2001;193:35-49 pubmed
Ellmeier W, Jung S, Sunshine M, Hatam F, Xu Y, Baltimore D, et al. Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk. J Exp Med. 2000;192:1611-24 pubmed
Lenz L, Butz E, Bevan M. Requirements for bone marrow-derived antigen-presenting cells in priming cytotoxic T cell responses to intracellular pathogens. J Exp Med. 2000;192:1135-42 pubmed
Scanga C, Mohan V, Yu K, Joseph H, Tanaka K, Chan J, et al. Depletion of CD4(+) T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon gamma and nitric oxide synthase 2. J Exp Med. 2000;192:347-58 pubmed
Costello P, Cleverley S, Galandrini R, Henning S, Cantrell D. The GTPase rho controls a p53-dependent survival checkpoint during thymopoiesis. J Exp Med. 2000;192:77-85 pubmed
Kitani A, Fuss I, Nakamura K, Schwartz O, Usui T, Strober W. Treatment of experimental (Trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-beta1 plasmid: TGF-beta1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction . J Exp Med. 2000;192:41-52 pubmed
Chvatchko Y, Hoogewerf A, Meyer A, Alouani S, Juillard P, Buser R, et al. A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock. J Exp Med. 2000;191:1755-64 pubmed
Horai R, Saijo S, Tanioka H, Nakae S, Sudo K, Okahara A, et al. Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. J Exp Med. 2000;191:313-20 pubmed
Nishimura H, Yajima T, Naiki Y, Tsunobuchi H, Umemura M, Itano K, et al. Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo. J Exp Med. 2000;191:157-70 pubmed
产品信息
Cat.# :
557306
品牌 :
BD Pharmingen
名称 :
CD3e
格式 :
纯化
克隆 :
145-2C11
抗体亚型 :
Ar Ham IgG 1
反应 :
Ms
浓度 :
0.5毫克/毫升
Apps :
FCM , IHC(Fr
规格 :
0.1毫克
状态 :
RUO
更多信息或购买 :
公司信息
碧迪BD
上海市南京西路1168号中信泰富广场30楼
http://www.bd.com/china
021-32104610