产品简要
公司名称 :
碧迪BD
其他品牌 :
Transduction Laboratories, PharMingen, Difco
产品类型 :
抗体
产品名称 :
Paxillin
目录 :
610051
规格 :
50微克
价格 :
207.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
349/Paxillin
反应物种 :
人类, 小鼠, 大鼠, , , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片, 其他
更多信息或购买 :
文章摘录数: 55
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 图 s5e
Freeman S, Uderhardt S, Saric A, Collins R, Buckley C, Mylvaganam S, et al. Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance. Science. 2020;367:301-305 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s7g
Kalappurakkal J, Anilkumar A, Patra C, van Zanten T, Sheetz M, Mayor S. Integrin Mechano-chemical Signaling Generates Plasma Membrane Nanodomains that Promote Cell Spreading. Cell. 2019;: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s5b
Schell C, Sabass B, Helmstaedter M, Geist F, Abed A, Yasuda Yamahara M, et al. ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier. Dev Cell. 2018;47:741-757.e8 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5c
Chen X, Wanggou S, Bodalia A, Zhu M, Dong W, Fan J, et al. A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression. Neuron. 2018;100:799-815.e7 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2a
Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3b
Wu Y, Jhao Y, Cheng Y, Chen Y. 15-Deoxy-?12,14-prostaglandin J2 inhibits migration of human thyroid carcinoma cells by disrupting focal adhesion complex and adherens junction. Oncol Lett. 2017;13:2569-2576 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 2e
Heim J, Squirewell E, Neu A, Zocher G, Sominidi Damodaran S, Wyles S, et al. Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix. Proc Natl Acad Sci U S A. 2017;114:3933-3938 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:300; 图 4b
Benito Jardón M, Klapproth S, Gimeno LLuch I, Petzold T, Bharadwaj M, Müller D, et al. The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes. elife. 2017;6: pubmed 出版商
  • 免疫细胞化学; 人类; 图 3a
Frank S, Köllmann C, van Lidth de Jeude J, Thiagarajah J, Engelholm L, Frödin M, et al. The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. Oncogene. 2017;36:1816-1828 pubmed 出版商
  • 免疫细胞化学; 犬; 图 3e
  • 免疫细胞化学; 人类; 图 1d
Taneja N, Fenix A, Rathbun L, Millis B, Tyska M, Hehnly H, et al. Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Sci Rep. 2016;6:29846 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7a
Hashimoto Tane A, Sakuma M, Ike H, Yokosuka T, Kimura Y, Ohara O, et al. Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation. J Exp Med. 2016;213:1609-25 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 s3
  • 免疫细胞化学; 小鼠; 1:200; 图 5
  • 免疫印迹; 小鼠; 1:1000; 图 4
Fusté N, Fernández Hernández R, Cemeli T, Mirantes C, Pedraza N, Rafel M, et al. Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nat Commun. 2016;7:11581 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Jadav R, Kumar D, Buwa N, Ganguli S, Thampatty S, Balasubramanian N, et al. Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice. Cell Signal. 2016;28:1124-36 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Marcos Ramiro B, García Weber D, Barroso S, Feito J, Ortega M, Cernuda Morollón E, et al. RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border. J Cell Biol. 2016;213:385-402 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 2c
  • 免疫印迹; 小鼠; 1:1000; 图 s1e
Nader G, Ezratty E, Gundersen G. FAK, talin and PIPKI? regulate endocytosed integrin activation to polarize focal adhesion assembly. Nat Cell Biol. 2016;18:491-503 pubmed 出版商
  • 免疫细胞化学; 斑马鱼; 1:100; 图 1
  • 免疫印迹; 斑马鱼; 1:1000; 图 s2
Hirth S, Bühler A, Bührdel J, Rudeck S, Dahme T, Rottbauer W, et al. Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart. PLoS ONE. 2016;11:e0150323 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s5
Kenific C, Stehbens S, Goldsmith J, Leidal A, Faure N, Ye J, et al. NBR1 enables autophagy-dependent focal adhesion turnover. J Cell Biol. 2016;212:577-90 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 6
  • 免疫印迹; 人类; 1:1000; 图 5
Horton E, Humphries J, Stutchbury B, Jacquemet G, Ballestrem C, Barry S, et al. Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition. J Cell Biol. 2016;212:349-64 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400; 图 1
  • 免疫印迹; 小鼠; 1:1000; 图 4
Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed 出版商
  • 其他; 人类; 图 st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 1a
Calvo F, Ranftl R, Hooper S, Farrugia A, Moeendarbary E, Bruckbauer A, et al. Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts. Cell Rep. 2015;13:2699-714 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 s2
Austen K, Ringer P, Mehlich A, Chrostek Grashoff A, Kluger C, Klingner C, et al. Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Nat Cell Biol. 2015;17:1597-606 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2
Kosmalska A, Casares L, Elosegui Artola A, Thottacherry J, Moreno Vicente R, González Tarragó V, et al. Physical principles of membrane remodelling during cell mechanoadaptation. Nat Commun. 2015;6:7292 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Case L, Baird M, Shtengel G, Campbell S, Hess H, Davidson M, et al. Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions. Nat Cell Biol. 2015;17:880-92 pubmed 出版商
  • 免疫细胞化学; 人类
Fukumoto M, Kurisu S, Yamada T, Takenawa T. α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation. PLoS ONE. 2015;10:e0120616 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
  • 免疫细胞化学; 人类; 1:200; 图 6
Robertson J, Jacquemet G, Byron A, Jones M, Warwood S, Selley J, et al. Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling. Nat Commun. 2015;6:6265 pubmed 出版商
  • 免疫印迹; 人类
Ng D, Humphries J, Byron A, Millon Frémillon A, Humphries M. Microtubule-dependent modulation of adhesion complex composition. PLoS ONE. 2014;9:e115213 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Gill M, Turner R, Stevenson P, Way M. KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction. EMBO J. 2015;34:448-65 pubmed 出版商
  • 免疫细胞化学; 人类; 10 ug/ml; 图 2
Georgess D, Mazzorana M, Terrado J, Delprat C, Chamot C, Guasch R, et al. Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts. Mol Biol Cell. 2014;25:380-96 pubmed 出版商
Jain P, Guerreiro P, Canato S, Janody F. The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis. Sci Rep. 2019;9:19843 pubmed 出版商
Cortés E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe S, et al. GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment. EMBO Rep. 2019;20: pubmed 出版商
Ikeuchi T, de Vega S, Forcinito P, Doyle A, Amaral J, Rodriguez I, et al. Extracellular Protein Fibulin-7 and Its C-Terminal Fragment Have In Vivo Antiangiogenic Activity. Sci Rep. 2018;8:17654 pubmed 出版商
Liao G, Wang R, Rezey A, Gerlach B, Tang D. MicroRNA miR-509 Regulates ERK1/2, the Vimentin Network, and Focal Adhesions by Targeting Plk1. Sci Rep. 2018;8:12635 pubmed 出版商
Panagiotakopoulou M, Lendenmann T, Pramotton F, Giampietro C, Stefopoulos G, Poulikakos D, et al. Cell cycle-dependent force transmission in cancer cells. Mol Biol Cell. 2018;29:2528-2539 pubmed 出版商
Chen P, Muzumdar M, Dorans K, Robbins R, Bhutkar A, Del Rosario A, et al. Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells. Cancer Res. 2018;78:985-1002 pubmed 出版商
Zhu L, Yang J, Bromberger T, Holly A, Lu F, Liu H, et al. Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation. Nat Commun. 2017;8:1744 pubmed 出版商
Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proc Natl Acad Sci U S A. 2017;114:E9280-E9289 pubmed 出版商
Luo W, Janostiak R, Tolde O, Ryzhova L, Koudelková L, Dibus M, et al. ARHGAP42 is activated by Src-mediated tyrosine phosphorylation to promote cell motility. J Cell Sci. 2017;130:2382-2393 pubmed 出版商
Goicoechea S, Zinn A, Awadia S, Snyder K, Garcia Mata R. A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells. J Cell Sci. 2017;130:1064-1077 pubmed 出版商
Mercey O, Popa A, Cavard A, Paquet A, Chevalier B, Pons N, et al. Characterizing isomiR variants within the microRNA-34/449 family. FEBS Lett. 2017;591:693-705 pubmed 出版商
Lim I, Joo H, Jeong M, Kim J, Choi S, Kim C, et al. Talin Modulation by a Synthetic N-Acylurea Derivative Reduces Angiogenesis in Human Endothelial Cells. Int J Mol Sci. 2017;18: pubmed 出版商
Albecka A, Owen D, Ivanova L, Brun J, Liman R, Davies L, et al. Dual Function of the pUL7-pUL51 Tegument Protein Complex in Herpes Simplex Virus 1 Infection. J Virol. 2017;91: pubmed 出版商
Chronopoulos A, Robinson B, Sarper M, Cortés E, Auernheimer V, Lachowski D, et al. ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion. Nat Commun. 2016;7:12630 pubmed 出版商
Moazzam M, Ye L, Sun P, Kynaston H, Jiang W. Knockdown of WAVE3 impairs HGF induced migration and invasion of prostate cancer cells. Cancer Cell Int. 2015;15:51 pubmed 出版商
Moshfegh Y, Bravo Cordero J, Miskolci V, Condeelis J, Hodgson L. A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly. Nat Cell Biol. 2014;16:574-86 pubmed 出版商
Rognoni E, Widmaier M, Jakobson M, Ruppert R, Ussar S, Katsougkri D, et al. Kindlin-1 controls Wnt and TGF-? availability to regulate cutaneous stem cell proliferation. Nat Med. 2014;20:350-9 pubmed 出版商
Yamazaki D, Itoh T, Miki H, Takenawa T. srGAP1 regulates lamellipodial dynamics and cell migratory behavior by modulating Rac1 activity. Mol Biol Cell. 2013;24:3393-405 pubmed 出版商
Vyas S, Chesarone Cataldo M, Todorova T, Huang Y, Chang P. A systematic analysis of the PARP protein family identifies new functions critical for cell physiology. Nat Commun. 2013;4:2240 pubmed 出版商
Kostourou V, Lechertier T, Reynolds L, Lees D, Baker M, Jones D, et al. FAK-heterozygous mice display enhanced tumour angiogenesis. Nat Commun. 2013;4:2020 pubmed 出版商
Tezuka Y, Okada M, Tada Y, Yamauchi J, Nishigori H, Sanbe A. Regulation of neurite growth by inorganic pyrophosphatase 1 via JNK dephosphorylation. PLoS ONE. 2013;8:e61649 pubmed 出版商
Matthews H, Delabre U, Rohn J, Guck J, Kunda P, Baum B. Changes in Ect2 localization couple actomyosin-dependent cell shape changes to mitotic progression. Dev Cell. 2012;23:371-83 pubmed 出版商
Lahlou H, Sanguin Gendreau V, Frame M, Muller W. Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo. Breast Cancer Res. 2012;14:R36 pubmed
Hewer R, Sala Newby G, Wu Y, Newby A, Bond M. PKA and Epac synergistically inhibit smooth muscle cell proliferation. J Mol Cell Cardiol. 2011;50:87-98 pubmed 出版商
Millan J, Cain R, Reglero Real N, Bigarella C, Marcos Ramiro B, Fernández Martín L, et al. Adherens junctions connect stress fibres between adjacent endothelial cells. BMC Biol. 2010;8:11 pubmed 出版商
ten Klooster J, Jaffer Z, Chernoff J, Hordijk P. Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix. J Cell Biol. 2006;172:759-69 pubmed
产品信息
Cat.# :
610051
品牌 :
BD Transduction Laboratories
名称 :
Paxillin
格式 :
纯化
克隆 :
349/Paxillin
抗体亚型 :
Ms IgG 1
反应 :
Hu , Ms , Rat , Dog , Chick
浓度 :
250微克/毫升
Apps :
IF, 免疫组化(F)*, 免疫沉淀, 免疫印迹
规格 :
50微克
状态 :
RUO
标价 :
207.00美元
更多信息或购买 :
公司信息
碧迪BD
上海市南京西路1168号中信泰富广场30楼
http://www.bd.com/china
021-32104610