| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Chen S, Yun F, Yao Y, Cao M, Zhang Y, Wang J, et al. USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein. J Exp Med. 2018;215:2850-2867 pubmed 出版商 |
| Dustrude E, Moutal A, Yang X, Wang Y, Khanna M, Khanna R. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function. Proc Natl Acad Sci U S A. 2016;113:E8443-E8452 pubmed 出版商 |
| Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, et al. Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner. Cell Discov. 2016;2:15044 pubmed 出版商 |
- 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 5
- 免疫沉淀; 小鼠; 图 3
| Kathania M, Khare P, Zeng M, Cantarel B, Zhang H, Ueno H, et al. Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-?t ubiquitination. Nat Immunol. 2016;17:997-1004 pubmed 出版商 |
| O Leary C, Riling C, Spruce L, Ding H, Kumar S, Deng G, et al. Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells. Nat Commun. 2016;7:11226 pubmed 出版商 |
- 其他; 人类; 图 st1
- 免疫印迹; 人类; 图 st4
| Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed 出版商 |
| Stöhr R, Mavilio M, Marino A, Casagrande V, Kappel B, Möllmann J, et al. ITCH modulates SIRT6 and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE null mice. Sci Rep. 2015;5:9023 pubmed 出版商 |
- 免疫印迹; 小鼠; 图 3
- 免疫沉淀; 人类; 图 3
| Kathania M, Zeng M, Yadav V, Moghaddam S, Yang B, Venuprasad K. Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7. J Immunol. 2015;194:2160-7 pubmed 出版商 |
| Moerdyk Schauwecker M, Hwang S, Grdzelishvili V. Cellular proteins associated with the interior and exterior of vesicular stomatitis virus virions. PLoS ONE. 2014;9:e104688 pubmed 出版商 |
| Pranski E, Dalal N, Sanford C, Herskowitz J, Gearing M, Lazo C, et al. RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-?B signaling in dopaminergic cells. Neurobiol Dis. 2013;54:264-79 pubmed 出版商 |
| Moreno Garcia M, Sommer K, Rincón Arano H, Brault M, Ninomiya Tsuji J, Matesic L, et al. Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-?B activation. Mol Cell Biol. 2013;33:1149-63 pubmed 出版商 |
| Ahmed N, Zeng M, Sinha I, Polin L, Wei W, Rathinam C, et al. The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation. Nat Immunol. 2011;12:1176-83 pubmed 出版商 |
| Shembade N, Ma A, Harhaj E. Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. Science. 2010;327:1135-9 pubmed 出版商 |
| Li X, Sun W, Li J, Wang M, Zhang H, Pei L, et al. Clomipramine causes osteoporosis by promoting osteoclastogenesis via E3 ligase Itch, which is prevented by Zoledronic acid. Sci Rep. 2017;7:41358 pubmed 出版商 |
| Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu Y. The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells. Nat Immunol. 2014;15:657-66 pubmed 出版商 |
| Pranski E, Dalal N, Herskowitz J, Orr A, Roesch L, Fritz J, et al. Neuronal RING finger protein 11 (RNF11) regulates canonical NF-?B signaling. J Neuroinflammation. 2012;9:67 pubmed 出版商 |
