产品简要
公司名称 :
Bethyl
产品类型 :
抗体
产品名称 :
兔抗HIF1甲抗体, 亲和纯化
目录 :
A300-286A
规格 :
20微克
价格 :
339美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , proximity ligation assay
更多信息或购买 :
文章摘录数: 31
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 小鼠; 图 1b
Yuan X, Qi H, Li X, Wu F, Fang J, Bober E, et al. Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. J Clin Invest. 2017;127:2235-2248 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Bizzarro V, Belvedere R, Migliaro V, Romano E, Parente L, Petrella A. Hypoxia regulates ANXA1 expression to support prostate cancer cell invasion and aggressiveness. Cell Adh Migr. 2017;11:247-260 pubmed 出版商
  • proximity ligation assay; 小鼠; 1:1000; 图 2a
Chen W, Hill H, Christie A, Kim M, Holloman E, Pavía Jiménez A, et al. Targeting renal cell carcinoma with a HIF-2 antagonist. Nature. 2016;539:112-117 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Jain I, Zazzeron L, Goli R, Alexa K, Schatzman Bone S, Dhillon H, et al. Hypoxia as a therapy for mitochondrial disease. Science. 2016;352:54-61 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2
  • 染色质免疫沉淀 ; 人类; 图 2
  • 免疫印迹; 人类; 1:1000; 图 2
Ding M, Bruick R, Yu Y. Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling. Nat Cell Biol. 2016;18:319-27 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Murata Y, Uehara Y, Hosoi Y. Activation of mTORC1 under nutrient starvation conditions increases cellular radiosensitivity in human liver cancer cell lines, HepG2 and HuH6. Biochem Biophys Res Commun. 2015;468:684-90 pubmed 出版商
  • 免疫印迹; 人类
Finger E, Cheng C, Williams T, Rankin E, Bedogni B, Tachiki L, et al. CTGF is a therapeutic target for metastatic melanoma. Oncogene. 2014;33:1093-100 pubmed 出版商
  • 免疫印迹; 人类
Isaacs J, Antony L, Dalrymple S, Brennen W, Gerber S, Hammers H, et al. Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Cancer Res. 2013;73:1386-99 pubmed 出版商
Bruno T, Valerio M, Casadei L, De Nicola F, Goeman F, Pallocca M, et al. Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization. J Exp Clin Cancer Res. 2017;36:32 pubmed 出版商
Sorrentino C, Miele L, Porta A, Pinto A, Morello S. Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAP-positive tumor stromal cells, enhancing tumor progression. Oncotarget. 2016;7:64274-64288 pubmed 出版商
Wei K, Piecewicz S, McGinnis L, Taniguchi C, Wiegand S, Anderson K, et al. A liver Hif-2?-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. Nat Med. 2013;19:1331-1337 pubmed 出版商
Aslam M, Schluter K, Rohrbach S, Rafiq A, Nazli S, Piper H, et al. Hypoxia-reoxygenation-induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase. J Physiol. 2013;591:461-73 pubmed 出版商
El Filali M, Ly L, Luyten G, Versluis M, Grossniklaus H, van der Velden P, et al. Bevacizumab and intraocular tumors: an intriguing paradox. Mol Vis. 2012;18:2454-67 pubmed
Hamidi T, Cano C, Grasso D, Garcia M, Sandi M, Calvo E, et al. Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death. Clin Cancer Res. 2012;18:5234-46 pubmed 出版商
Ji K, Tsirka S. Inflammation modulates expression of laminin in the central nervous system following ischemic injury. J Neuroinflammation. 2012;9:159 pubmed 出版商
Zhang L, Das P, Schmolke M, Manicassamy B, Wang Y, Deng X, et al. Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export. J Cell Biol. 2012;196:315-26 pubmed 出版商
Hong S, Jin D, Buck D, Galiano R, Mustoe T. Impaired response of mature adipocytes of diabetic mice to hypoxia. Exp Cell Res. 2011;317:2299-307 pubmed 出版商
Holmberg J, He X, Peredo I, Orrego A, Hesselager G, Ericsson C, et al. Activation of neural and pluripotent stem cell signatures correlates with increased malignancy in human glioma. PLoS ONE. 2011;6:e18454 pubmed 出版商
Wolff N, Vega Rubin de Celis S, Xie X, Castrillon D, Kabbani W, Brugarolas J. Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia. Mol Cell Biol. 2011;31:1870-84 pubmed 出版商
Xu D, Yao Y, Lu L, Costa M, Dai W. Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha. J Biol Chem. 2010;285:38944-50 pubmed 出版商
Welford S, Dorie M, Li X, Haase V, Giaccia A. Renal oxygenation suppresses VHL loss-induced senescence that is caused by increased sensitivity to oxidative stress. Mol Cell Biol. 2010;30:4595-603 pubmed 出版商
Mendez O, Zavadil J, Esencay M, Lukyanov Y, Santovasi D, Wang S, et al. Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. Mol Cancer. 2010;9:133 pubmed 出版商
Lu Z, Shvartsman M, Lee A, Shao J, Murray M, Kladney R, et al. Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis. Cancer Res. 2010;70:3287-98 pubmed 出版商
Costa B, Dettori D, Lorenzato A, Bardella C, Coltella N, Martino C, et al. Fumarase tumor suppressor gene and MET oncogene cooperate in upholding transformation and tumorigenesis. FASEB J. 2010;24:2680-8 pubmed 出版商
El Filali M, Missotten G, Maat W, Ly L, Luyten G, van der Velden P, et al. Regulation of VEGF-A in uveal melanoma. Invest Ophthalmol Vis Sci. 2010;51:2329-37 pubmed 出版商
Porcelli A, Ghelli A, Ceccarelli C, Lang M, Cenacchi G, Capristo M, et al. The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization. Hum Mol Genet. 2010;19:1019-32 pubmed 出版商
Loinard C, Ginouves A, Vilar J, Cochain C, Zouggari Y, Recalde A, et al. Inhibition of prolyl hydroxylase domain proteins promotes therapeutic revascularization. Circulation. 2009;120:50-9 pubmed 出版商
Vasseur S, Afzal S, Tardivel Lacombe J, Park D, Iovanna J, Mak T. DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses. Proc Natl Acad Sci U S A. 2009;106:1111-6 pubmed 出版商
Shui Y, Arbeit J, Johnson R, Beebe D. HIF-1: an age-dependent regulator of lens cell proliferation. Invest Ophthalmol Vis Sci. 2008;49:4961-70 pubmed 出版商
Yang Y, Bai J, Shen R, Brown S, Komissarova E, Huang Y, et al. Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions. Cancer Res. 2008;68:4077-85 pubmed 出版商
Scortegagna M, Cataisson C, Martin R, Hicklin D, Schreiber R, Yuspa S, et al. HIF-1alpha regulates epithelial inflammation by cell autonomous NFkappaB activation and paracrine stromal remodeling. Blood. 2008;111:3343-54 pubmed 出版商
产品信息
目录代码 :
A300-286A
产品名称 :
兔抗HIF1甲抗体, 亲和纯化
宿主物种 :
共轭 :
未共轭
浓度 :
100 µl at 0.2 mg/ml
规格 :
20微克
包装 :
100微升(0.2毫克/毫升)
缓冲液 :
三羟甲基氨基甲烷缓冲盐液含0.1% BSA和0.09% 叠氮化钠
物种摘要 :
人类, 小鼠
应用摘要 :
免疫印迹, 免疫沉淀, 免疫组化, 免疫细胞化学-IF, PLA
储存 :
2 - 8° C
标价 :
339美元
别名 :
ARNT interacting protein, ARNT-interacting protein, basic-helix-loop-helix-PAS protein MOP1, bHLHe78, class E basic helix-loop-helix protein 78, HIF1, HIF-1A, HIF-1alpha, HIF-1-alpha, HIF1-ALPHA, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1 alpha isoform I.3, hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor1alpha, member of PAS protein 1, member of PAS superfamily 1, MOP1, PAS domain-containing protein 8, PASD8
产品类型 :
一抗
免疫原 :
Between 775 and C-term
更多信息或购买 :
公司信息
Bethyl
25043 West FM 1097 Montgomery, TX 77356 USA
technical@bethyl.com
www.bethyl.com
936-597-6111 1-800-338-9579