产品简要
公司名称 :
Bethyl
产品类型 :
抗体
产品名称 :
兔抗MAD2抗体, 亲和纯化
目录 :
A300-301A
规格 :
100微克
价格 :
339美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, proximity ligation assay, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 34
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:5000; 图 3a
Ruppert J, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash A, et al. HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry. EMBO J. 2018;37: pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Faisal A, Mak G, Gurden M, Xavier C, Anderhub S, Innocenti P, et al. Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy. Br J Cancer. 2017;116:1166-1176 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 5
Fong C, Mazo G, Das T, Goodman J, Kim M, O Rourke B, et al. 53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Salsi V, Fantini S, Zappavigna V. NUP98 fusion oncoproteins interact with the APC/C(Cdc20) as a pseudosubstrate and prevent mitotic checkpoint complex binding. Cell Cycle. 2016;15:2275-87 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 1:1000; 图 1c
  • 免疫印迹; 人类; 1:1000
Sedgwick G, Larsen M, Lischetti T, Streicher W, Jersie Christensen R, Olsen J, et al. Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling. MAbs. 2016;8:689-97 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 s4
Wild T, Larsen M, Narita T, Schou J, Nilsson J, Choudhary C. The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity. Cell Rep. 2016;14:1829-40 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6
Baron A, von Schubert C, Cubizolles F, Siemeister G, Hitchcock M, Mengel A, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7c
Sharma B, Kolhe R, Black S, Keller J, Mivechi N, Satyanarayana A. Inhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells. FASEB J. 2016;30:262-75 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Voets E, Marsman J, Demmers J, Beijersbergen R, Wolthuis R. The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1. Sci Rep. 2015;5:14798 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 1
Milev M, Hasaj B, Saint Dic D, Snounou S, Zhao Q, Sacher M. TRAMM/TrappC12 plays a role in chromosome congression, kinetochore stability, and CENP-E recruitment. J Cell Biol. 2015;209:221-34 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 s1
Czechanski A, Kim H, Byers C, Greenstein I, Stumpff J, Reinholdt L. Kif18a is specifically required for mitotic progression during germ line development. Dev Biol. 2015;402:253-262 pubmed 出版商
  • 免疫细胞化学; 人类
Brownlow N, Pike T, Zicha D, Collinson L, Parker P. Mitotic catenation is monitored and resolved by a PKCε-regulated pathway. Nat Commun. 2014;5:5685 pubmed 出版商
  • 免疫沉淀; 人类; 1:500; 图 4
  • 免疫细胞化学; 人类
Izawa D, Pines J. The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C. Nature. 2015;517:631-4 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Goldfarb D, Hast B, Wang W, Major M. Spotlite: web application and augmented algorithms for predicting co-complexed proteins from affinity purification--mass spectrometry data. J Proteome Res. 2014;13:5944-55 pubmed 出版商
  • 免疫沉淀; 人类; 图 2b
  • 免疫印迹; 人类; 1:1000; 图 6e
  • 免疫沉淀; 小鼠; 图 2d
  • 免疫印迹; 小鼠; 1:1000; 图 6e
Shandilya J, Toska E, Richard D, Medler K, Roberts S. WT1 interacts with MAD2 and regulates mitotic checkpoint function. Nat Commun. 2014;5:4903 pubmed 出版商
  • 免疫印迹; 人类
Yang X, Xu W, Hu Z, Zhang Y, Xu N. Chk1 is required for the metaphase-anaphase transition via regulating the expression and localization of Cdc20 and Mad2. Life Sci. 2014;106:12-8 pubmed 出版商
  • 免疫印迹; 人类
Rodriguez Bravo V, Maciejowski J, Corona J, Buch H, Collin P, Kanemaki M, et al. Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor. Cell. 2014;156:1017-31 pubmed 出版商
Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa M, Uriarte I, et al. Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. Nucleic Acids Res. 2019;47:3450-3466 pubmed 出版商
Champion L, Pawar S, Luithle N, Ungricht R, Kutay U. Dissociation of membrane-chromatin contacts is required for proper chromosome segregation in mitosis. Mol Biol Cell. 2019;30:427-440 pubmed 出版商
Kim D, Han J, Ly P, Ye Q, McMahon M, Myung K, et al. TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC. Nat Commun. 2018;9:4354 pubmed 出版商
Rashid M, Mazur T, Ji W, Liu S, Taylor W. Analysis of the role of GSK3 in the mitotic checkpoint. Sci Rep. 2018;8:14259 pubmed 出版商
Drpic D, Almeida A, Aguiar P, Renda F, Damas J, Lewin H, et al. Chromosome Segregation Is Biased by Kinetochore Size. Curr Biol. 2018;28:1344-1356.e5 pubmed 出版商
Skowyra A, Allan L, Saurin A, Clarke P. USP9X Limits Mitotic Checkpoint Complex Turnover to Strengthen the Spindle Assembly Checkpoint and Guard against Chromosomal Instability. Cell Rep. 2018;23:852-865 pubmed 出版商
Gurden M, Westwood I, Faisal A, Naud S, Cheung K, McAndrew C, et al. Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Res. 2015;75:3340-54 pubmed 出版商
Bauer M, Ahrné E, Baron A, Glatter T, Fava L, Santamaria A, et al. Evaluation of data-dependent and -independent mass spectrometric workflows for sensitive quantification of proteins and phosphorylation sites. J Proteome Res. 2014;13:5973-88 pubmed 出版商
Schweizer N, Ferrás C, Kern D, Logarinho E, Cheeseman I, Maiato H. Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis. J Cell Biol. 2013;203:883-93 pubmed
Albers J, Rajski M, Schönenberger D, Harlander S, Schraml P, von Teichman A, et al. Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice. EMBO Mol Med. 2013;5:949-64 pubmed 出版商
Beck J, Maerki S, Posch M, Metzger T, Persaud A, Scheel H, et al. Ubiquitylation-dependent localization of PLK1 in mitosis. Nat Cell Biol. 2013;15:430-9 pubmed 出版商
Sedgwick G, Hayward D, Di Fiore B, Pardo M, Yu L, Pines J, et al. Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex. EMBO J. 2013;32:303-14 pubmed 出版商
Izawa D, Pines J. Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation. J Cell Biol. 2012;199:27-37 pubmed 出版商
Sigoillot F, Lyman S, Huckins J, Adamson B, Chung E, Quattrochi B, et al. A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens. Nat Methods. 2012;9:363-6 pubmed 出版商
Mansfeld J, Collin P, Collins M, Choudhary J, Pines J. APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment. Nat Cell Biol. 2011;13:1234-43 pubmed 出版商
Kannan R, Hensley L, Evers L, Lemon S, McGivern D. Hepatitis C virus infection causes cell cycle arrest at the level of initiation of mitosis. J Virol. 2011;85:7989-8001 pubmed 出版商
Tipton A, Wang K, Link L, Bellizzi J, Huang H, Yen T, et al. BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex. J Biol Chem. 2011;286:21173-9 pubmed 出版商
产品信息
目录代码 :
A300-301A
产品名称 :
兔抗MAD2抗体, 亲和纯化
宿主物种 :
共轭 :
未共轭
浓度 :
100 µl at 1 mg/ml
规格 :
100微克
包装 :
100微升(1毫克/毫升)
缓冲液 :
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
物种摘要 :
人类, 小鼠
应用摘要 :
免疫印迹, 免疫沉淀, PLA
储存 :
2 - 8° C
标价 :
339美元
别名 :
HSMAD2, MAD2, MAD2 (mitotic arrest deficient, yeast, homolog)-like 1, MAD2-like protein 1, mitotic arrest deficient 2-like protein 1, mitotic arrest deficient, yeast, homolog-like 1
产品类型 :
一抗
免疫原 :
Between 150 and C-term
更多信息或购买 :
公司信息
Bethyl
25043 West FM 1097 Montgomery, TX 77356 USA
technical@bethyl.com
https://www.bethyl.com
936-597-6111 1-800-338-9579