产品简要
公司名称 :
Bio-Ocean
产品类型 :
ELISA/assay
产品名称 :
人类IL-13酶联免疫吸附试剂盒
目录 :
EK113
规格 :
96 well test
价格 :
349美元
更多信息或购买 :
产品信息
目录代码 :
EK113
产品名称 :
人类IL-13酶联免疫吸附试剂盒
宿主物种 :
人类
产品类型 :
酶联免疫吸附测定
规格 :
96 well test
标价 :
349美元
产品描述 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-13. The Human IL-13 ELISA is for research use only. Not for diagnostic or therapeutic procedures. IL-13 is located on chromosome 5q31 with a length of 1.4kb. IL-13 and IL-4 exhibit a 30% of sequence similarity and have a similar structure. IL-13 is cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells. IL-13 has effects on immune cells that are similar to those of the closely related cytokine IL-4. Although IL-13 is associated primarily with the induction of airway disease, it also has anti-inflammatory properties. IL-13 is known to induce changes in hematopoietic cells, but these effects are probably less important than that of IL-4. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. IL-13 specifically induces physiological changes in parasitized organs that are required to expel the offending organisms or their products. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cellmetaplasia and mucus hypersecretion, which all contribute to airway obstruction. Furthermore, IL-13 inhibits HIV-1 replication in primary culture-derived macrophages and represents a candidate cytokine for the suppression of HIV infection within monocytes and macrophages in vivo.
更多信息或购买 :
公司信息
Bio-Ocean
3550 Lexington Ave, Suite 203, Shoreview, Minnesota 55126
info@bioocean.com
www.bioocean.com
1-800-852-7601
公司总部: 美国