产品简要
公司名称 :
Bio-Ocean
产品类型 :
ELISA/assay
产品名称 :
人类sCD40L酶联免疫吸附试剂盒
目录 :
EK188
规格 :
96 well test
价格 :
349美元
更多信息或购买 :
产品信息
目录代码 :
EK188
产品名称 :
人类sCD40L酶联免疫吸附试剂盒
宿主物种 :
人类
产品类型 :
酶联免疫吸附测定
规格 :
96 well test
标价 :
349美元
产品描述 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human sCD40L. The Human sCD40L ELISA is for research use only. Not for diagnostic or therapeutic procedures. CD40 ligand (CD40L, CD154) is a member of the TNF superfamily of molecules and is a CD40L is a 39 kDa glycoprotein that is primarily expressed on activated T cells. 15-18 kDa soluble forms of CD40L (sCD40L) is produced by proteolytic cleavage. CD40L binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. CD40L acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells (TFH cells). On Tfh cells, CD40L promotes B cell maturation and function by engaging CD40 on the B cell surface and therefore facilitating cell-cell communication. Monitoring of MCP-1 levels in serum provides more detailed insights in several pathological situations such as acquired immune deficiency syndrome (AIDS), systemic lupus erythematosus (SLE), chronic lymphocytic leukemia (CLL), unstable angina, atherosclerosis and acute coronary syndromes.
更多信息或购买 :
公司信息
Bio-Ocean
3550 Lexington Ave, Suite 203, Shoreview, Minnesota 55126
info@bioocean.com
www.bioocean.com
1-800-852-7601
公司总部: 美国