产品简要
公司名称 :
伯乐（Bio-Rad）公司
其他品牌 :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
产品类型 :
抗体
产品名称 :
大鼠抗MOUSE F4/80:Low内毒素
目录 :
MCA497EL
规格 :
0.5毫克
价格 :
622美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
Cl:A3-1
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
伯乐（Bio-Rad）公司 产品网页
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 7a
Huang Z, Liu S, Tang A, Al Rabadi L, Henkemeyer M, Mimche P, et al. Key role for EphB2 receptor in kidney fibrosis. Clin Sci (Lond). 2021;135:2127-2142 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a, s2b
Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2a
Sorrentino C, Yin Z, Ciummo S, Lanuti P, Lu L, Marchisio M, et al. Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival. J Immunother Cancer. 2019;7:201 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s2a, s2b
Aarts S, Seijkens T, Kusters P, Van Tiel C, Reiche M, den Toom M, et al. Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis. J Pathol. 2019;247:471-480 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 1b
Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch S, et al. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018;128:1852-1866 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 6h
Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018;9:75 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
A Gonzalez N, Quintana J, Garcia Silva S, Mazariegos M, González de la Aleja A, Nicolás Ávila J, et al. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med. 2017;214:1281-1296 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 s1
Lim E, Nakanishi S, Hoghooghi V, Eaton S, Palmer A, Frederick A, et al. AlphaB-crystallin regulates remyelination after peripheral nerve injury. Proc Natl Acad Sci U S A. 2017;114:E1707-E1716 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s1c
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar -, et al. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 2016;167:1264-1280.e18 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 S7A
Troegeler A, Mercier I, Cougoule C, Pietretti D, Colom A, Duval C, et al. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc Natl Acad Sci U S A. 2017;114:E540-E549 pubmed 出版商
  • 免疫组化; 小鼠; 图 6a
Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s2
Fransén Pettersson N, Duarte N, Nilsson J, Lundholm M, Mayans S, Larefalk A, et al. A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis. PLoS ONE. 2016;11:e0159850 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5
Tsuboki J, Fujiwara Y, Horlad H, Shiraishi D, Nohara T, Tayama S, et al. Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages. Sci Rep. 2016;6:29588 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Brandstätter O, Schanz O, Vorac J, König J, Mori T, Maruyama T, et al. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016;6:26091 pubmed 出版商
  • 免疫组化; 小鼠; 图 1
Hirasawa M, Takubo K, Osada H, Miyake S, Toda E, Endo M, et al. Angiopoietin-like Protein 2 Is a Multistep Regulator of Inflammatory Neovascularization in a Murine Model of Age-related Macular Degeneration. J Biol Chem. 2016;291:7373-85 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed 出版商
  • 流式细胞仪; 小鼠
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4a
Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed 出版商
  • 流式细胞仪; 小鼠
Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, et al. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 2015;42:1143-58 pubmed 出版商
  • 流式细胞仪; 人类
Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, et al. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. J Immunol. 2015;194:1819-31 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Evrard M, Chong S, Devi S, Chew W, Lee B, Poidinger M, et al. Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L-/- reporter mouse by multiphoton intravital microscopy. J Leukoc Biol. 2015;97:611-9 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 4b
Jannasch K, Wegwitz F, Lenfert E, Maenz C, Deppert W, Alves F. Chemotherapy of WAP-T mouse mammary carcinomas aggravates tumor phenotype and enhances tumor cell dissemination. Int J Cancer. 2015;137:25-36 pubmed 出版商
  • 免疫组化; 小鼠; 图 1
Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, et al. Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice. Arthritis Rheumatol. 2015;67:517-26 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 流式细胞仪; 小鼠
Liu G, Zhang W, Xiao Y, Lu P. Critical Role of IP-10 on Reducing Experimental Corneal Neovascularization. Curr Eye Res. 2015;40:891-901 pubmed 出版商
  • 流式细胞仪; 小鼠
Döring M, Lessin I, Frenz T, Spanier J, Kessler A, Tegtmeyer P, et al. M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells. J Virol. 2014;88:13638-50 pubmed 出版商
  • 流式细胞仪; 小鼠
Bernasconi E, D Angelo F, Michetti P, Velin D. Critical role of the GM-CSF signaling pathway in macrophage pro-repair activities. Pathobiology. 2014;81:183-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500
de Bock L, Somers K, Fraussen J, Hendriks J, van Horssen J, Rouwette M, et al. Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. J Immunol. 2014;193:2147-56 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200
Watatani H, Maeshima Y, Hinamoto N, Yamasaki H, Ujike H, Tanabe K, et al. Vasohibin-1 deficiency enhances renal fibrosis and inflammation after unilateral ureteral obstruction. Physiol Rep. 2014;2: pubmed 出版商
  • 流式细胞仪; 小鼠
Forgèt M, Voorhees J, Cole S, Dakhlallah D, Patterson I, Gross A, et al. Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer. PLoS ONE. 2014;9:e98623 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50
Orim F, Bychkov A, Shimamura M, Nakashima M, Ito M, Matsuse M, et al. Thyrotropin signaling confers more aggressive features with higher genomic instability on BRAF(V600E)-induced thyroid tumors in a mouse model. Thyroid. 2014;24:502-10 pubmed 出版商
Phillips E, Lorch A, Durkes A, Goergen C. Early pathological characterization of murine dissecting abdominal aortic aneurysms. APL Bioeng. 2018;2:046106 pubmed 出版商
Kortlever R, Sodir N, Wilson C, Burkhart D, Pellegrinet L, Brown Swigart L, et al. Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. Cell. 2017;171:1301-1315.e14 pubmed 出版商
Kennelly K, Holmes T, Wallace D, O Farrelly C, Keegan D. Early Subretinal Allograft Rejection Is Characterized by Innate Immune Activity. Cell Transplant. 2017;26:983-1000 pubmed 出版商
Hudson N, Powner M, Sarker M, Burgoyne T, Campbell M, Ockrim Z, et al. Differential apicobasal VEGF signaling at vascular blood-neural barriers. Dev Cell. 2014;30:541-52 pubmed 出版商
Khare R, Hillestad M, Xu Z, Byrnes A, Barry M. Circulating antibodies and macrophages as modulators of adenovirus pharmacology. J Virol. 2013;87:3678-86 pubmed 出版商
Fisher J, McKenzie T, Lillegard J, Yu Y, Juskewitch J, Nedredal G, et al. Role of Kupffer cells and toll-like receptor 4 in acetaminophen-induced acute liver failure. J Surg Res. 2013;180:147-55 pubmed 出版商
Pagani A, Nai A, Corna G, Bosurgi L, Rovere Querini P, Camaschella C, et al. Low hepcidin accounts for the proinflammatory status associated with iron deficiency. Blood. 2011;118:736-46 pubmed 出版商
Khare R, May S, Vetrini F, Weaver E, Palmer D, Rosewell A, et al. Generation of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer. Mol Ther. 2011;19:1254-62 pubmed 出版商
Ibe S, Qin Z, Schuler T, Preiss S, Blankenstein T. Tumor rejection by disturbing tumor stroma cell interactions. J Exp Med. 2001;194:1549-59 pubmed
图像
图像 1 :
伯乐（Bio-Rad）公司 MCA497EL 图像 1
Dot Blot showing FSC/SSC gated mouse peritoneal macrophages dual stained with F4/80 ( MCA497A647 ) at a 1/5 dilution and CD11b ( MCA74F ) at a 1/5 dilution. Isotype control pair in red. Fc receptors were blocked by Mouse Seroblock ( BUF041B )
产品信息
Entity Type :
单克隆抗体
Entity Category :
抗体
ProductCode :
MCA497EL
描述 :
大鼠抗MOUSE F4/80:Low内毒素
特异性 :
F4/80
目标物种 :
小鼠
宿主 :
大鼠
格式 :
低内毒素
Isotypes :
IgG2b
应用 :
C, FN, F, 免疫印迹, 免疫沉淀, P*, R, RE
ApplicationTypes :
Flow Cytometry,Western Blotting,Immunohistology - Frozen,Immunohistology - Paraffin,Immunoprecipitation,Radioimmunoassays,Functional Assays,Immunohistology - Resin
克隆 :
Cl:A3-1
规格 :
0.5毫克
Quantity Value :
0.5
规格类型 :
毫克
GO登录号 :
GO:0009897, GO:0007218, GO:0004930, GO:0016021, GO:0005509
GOTerms :
calcium ion storage activity,transmembrane,EBV-induced receptor,Epstein-Barr Virus-induced receptor activity,G protein coupled receptor activity,G protein linked receptor activity,GO:0001622,GO:0001623,GO:0001624,GO:0001625,GO:0016526,GPCR activity,G-protein coupled receptor activity, unknown ligand,G-protein linked receptor activity,G-protein-coupled receptor activity,ligand-dependent GPCR activity,Mas proto-oncogene receptor activity,orphan G protein coupled receptor activity,orphan GPCR activity,orphan G-protein coupled receptor activity,RDC1 receptor activity,SREB receptor,super conserved receptor expressed in brain receptor activity,neuropeptide signalling pathway,juxtamembrane,outer surface of cytoplasmic membrane
UniProt数据库登录号 :
Q61549
基因 :
Emr1
GeneID网址 :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=13733
Entity Formats :
ALEXA FLUOR® 405,ALEXA FLUOR® 488,ALEXA FLUOR® 647,ALEXA FLUOR® 700,Amethyst Blue,Amethyst Orange,APC,Biotin,DyLight®350,DyLight®680,FITC,Low Endotoxin,Pacific Blue®,Preservative Free,Purified,RPE,RPE-ALEXA FLUOR® 647,RPE-ALEXA FLUOR® 750,RPE-CY5,S/N,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 700,StarBright Blue 765,StarBright Blue 810,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815,StarBright UltraViolet 400,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright UltraViolet 665,StarBright UltraViolet 740,StarBright UltraViolet 795,StarBright Violet 440,StarBright Violet 475,StarBright Violet 515,StarBright Violet 570,StarBright Violet 610,StarBright Violet 670,StarBright Violet 710,StarBright Violet 760,StarBright Violet 790,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 720,StarBright Yellow 800
UNSPSC :
41116161
浓度 :
IgG浓度1毫克/毫升
产品形式 :
纯化IgG-液体
PriceGBP :
445
PriceEUR :
622
PriceUSD :
622美元
PriceCHF :
677
PriceSEK :
6780
PriceNOK :
6814
PriceDKK :
4637
更多信息或购买 :
伯乐（Bio-Rad）公司 产品网页
公司信息
伯乐（Bio-Rad）公司
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
44-1865-852-700
公司总部: 英国
伯乐（Bio-Rad）公司是世界领先的抗体生产商之一。通过其原名为AbD Serotec公司的专业抗体业务团队，提供超过12,000种抗体及相关试剂，专注于免疫学、肿瘤、兽医研究及细胞生物学等领域。
抗体产品包括细胞凋亡试剂盒，自噬检测试剂，CD分子标记物，标签抗体，免疫学研究抗体，神经科学研究抗体和兽医应用试剂等。
伯乐（Bio-Rad）公司在英国拥有经ISO9001和ISO13485认证的生产厂房，同时在德国和美国均设有经ISO9001认证的厂房。
我们专业领域已扩展到传统和重组抗体制备及生产服务。我们的抗体定制服务仅需8周就能完成抗体制备并且成功率在90%以上。我们的体外重组抗体技术能够使得我们筛选制备针对具有挑战性的靶点的抗体，确保长期稳定供货，并能够提供抗体的相应基因序列。
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