产品简要
公司名称 :
伯乐(Bio-Rad)公司
其他品牌 :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
产品类型 :
抗体
产品名称 :
大鼠抗MOUSE CD11b
目录 :
MCA711
规格 :
1毫克
价格 :
581美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
5C6
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 94
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 3b
Thygesen C, Ilkjær L, Kempf S, Hemdrup A, von Linstow C, Babcock A, et al. Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1ΔE9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease. Front Cell Neurosci. 2018;12:397 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2c
Betlazar C, Harrison Brown M, Middleton R, Banati R, Liu G. Cellular Sources and Regional Variations in the Expression of the Neuroinflammatory Marker Translocator Protein (TSPO) in the Normal Brain. Int J Mol Sci. 2018;19: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2a
Schuhmann M, Guthmann J, Stoll G, Nieswandt B, Kraft P, Kleinschnitz C. Blocking of platelet glycoprotein receptor Ib reduces "thrombo-inflammation" in mice with acute ischemic stroke. J Neuroinflammation. 2017;14:18 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:250; 图 1c
Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 2e
Thomsen M, Birkelund S, Burkhart A, Stensballe A, Moos T. Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier. J Neurochem. 2017;140:741-754 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 5
Christensen D, Ejlerskov P, Rasmussen I, Vilhardt F. Reciprocal signals between microglia and neurons regulate α-synuclein secretion by exophagy through a neuronal cJUN-N-terminal kinase-signaling axis. J Neuroinflammation. 2016;13:59 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:5000; 图 2
Hristova M, Rocha Ferreira E, Fontana X, Thei L, Buckle R, Christou M, et al. Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) reduces neonatal hypoxic-ischaemic brain damage. J Neurochem. 2016;136:981-94 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:100
Gautier H, Evans K, Volbracht K, James R, Sitnikov S, Lundgaard I, et al. Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors. Nat Commun. 2015;6:8518 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2
Chen H, Sun Y, Lai L, Wu H, Xiao Y, Ming B, et al. Interleukin-33 is released in spinal cord and suppresses experimental autoimmune encephalomyelitis in mice. Neuroscience. 2015;308:157-68 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 ev2
Zhao L, Zabel M, Wang X, Ma W, Shah P, Fariss R, et al. Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration. EMBO Mol Med. 2015;7:1179-97 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Kan M, Lee J, Wilson J, Everhart A, Brown C, Hoofnagle A, et al. Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. J Neurosci. 2015;35:5969-82 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:300
Zarruk J, Berard J, Passos Dos Santos R, Kroner A, Lee J, Arosio P, et al. Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation. Neurobiol Dis. 2015;81:93-107 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 5d
Filézac de L Etang A, Maharjan N, Cordeiro Braña M, Ruegsegger C, Rehmann R, Goswami A, et al. Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS. Nat Neurosci. 2015;18:227-38 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2
Lambertsen K, Østergaard K, Clausen B, Hansen S, Stenvang J, Thorsen S, et al. No effect of ablation of surfactant protein-D on acute cerebral infarction in mice. J Neuroinflammation. 2014;11:123 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 2
Tyzack G, Sitnikov S, Barson D, Adams Carr K, Lau N, Kwok J, et al. Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression. Nat Commun. 2014;5:4294 pubmed 出版商
  • 免疫组化; 小鼠
Tepavcevic V, Kerninon C, Aigrot M, Meppiel E, Mozafari S, Arnould Laurent R, et al. Early netrin-1 expression impairs central nervous system remyelination. Ann Neurol. 2014;76:252-68 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 5b
Neher M, Rich M, Keene C, Weckbach S, Bolden A, Losacco J, et al. Deficiency of complement receptors CR2/CR1 in Cr2?/? mice reduces the extent of secondary brain damage after closed head injury. J Neuroinflammation. 2014;11:95 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200
  • 免疫组化; 小鼠; 1:200
O Brien E, Kersemans V, Tredwell M, Checa B, Serres S, Soto M, et al. Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker. J Nucl Med. 2014;55:275-80 pubmed 出版商
  • 免疫组化; 小鼠; 1:500
  • 免疫印迹; 小鼠; 1:1000
Chittoor V, Sooyeon L, Rangaraju S, Nicks J, Schmidt J, Madorsky I, et al. Biochemical characterization of protein quality control mechanisms during disease progression in the C22 mouse model of CMT1A. ASN Neuro. 2013;5:e00128 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫组化; 小鼠
de Waard M, van der Pluijm I, Zuiderveen Borgesius N, Comley L, Haasdijk E, Rijksen Y, et al. Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice. Acta Neuropathol. 2010;120:461-75 pubmed 出版商
  • 免疫组化; 人类
Chaudhry U, Zhuang H, Crain B, DORE S. Elevated microsomal prostaglandin-E synthase-1 in Alzheimer's disease. Alzheimers Dement. 2008;4:6-13 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
Bulloch K, Miller M, Gal Toth J, Milner T, Gottfried Blackmore A, Waters E, et al. CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain. J Comp Neurol. 2008;508:687-710 pubmed 出版商
Bieber M, Schuhmann M, Volz J, Kumar G, Vaidya J, Nieswandt B, et al. Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function. Stroke. 2019;50:478-486 pubmed 出版商
Mouton Liger F, Rosazza T, Sepulveda Diaz J, Ieang A, Hassoun S, Claire E, et al. Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop. Glia. 2018;: pubmed 出版商
Rizzi C, Tiberi A, Giustizieri M, Marrone M, Gobbo F, Carucci N, et al. NGF steers microglia toward a neuroprotective phenotype. Glia. 2018;66:1395-1416 pubmed 出版商
Pulido Salgado M, Vidal Taboada J, Garcia Díaz Barriga G, Serratosa J, Valente T, Castillo P, et al. Myeloid C/EBP? deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2017;14:54 pubmed 出版商
Hopp S, Nolte M, Stetter C, Kleinschnitz C, SIREN A, Albert Weissenberger C. Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa. J Neuroinflammation. 2017;14:39 pubmed 出版商
Rabl R, Breitschaedel C, Flunkert S, Duller S, Amschl D, Neddens J, et al. Early start of progressive motor deficits in Line 61 ?-synuclein transgenic mice. BMC Neurosci. 2017;18:22 pubmed 出版商
Allodi I, Comley L, Nichterwitz S, Nizzardo M, Simone C, Benitez J, et al. Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS. Sci Rep. 2016;6:25960 pubmed 出版商
Wlodarczyk A, Cédile O, Jensen K, Jasson A, Mony J, Khorooshi R, et al. Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation. Front Immunol. 2015;6:463 pubmed 出版商
Alam J. Selective Brain-Targeted Antagonism of p38 MAPKα Reduces Hippocampal IL-1β Levels and Improves Morris Water Maze Performance in Aged Rats. J Alzheimers Dis. 2015;48:219-27 pubmed 出版商
Khorooshi R, Mørch M, Holm T, Berg C, Dieu R, Dræby D, et al. Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis. Acta Neuropathol. 2015;130:107-18 pubmed 出版商
Albert Weissenberger C, Mencl S, Schuhmann M, Salur I, Göb E, Langhauser F, et al. C1-Inhibitor protects from focal brain trauma in a cortical cryolesion mice model by reducing thrombo-inflammation. Front Cell Neurosci. 2014;8:269 pubmed 出版商
Mencl S, Hennig N, Hopp S, Schuhmann M, Albert Weissenberger C, SIREN A, et al. FTY720 does not protect from traumatic brain injury in mice despite reducing posttraumatic inflammation. J Neuroimmunol. 2014;274:125-31 pubmed 出版商
Löffler T, Flunkert S, Havas D, Schweinzer C, Uger M, Windisch M, et al. Neuroinflammation and related neuropathologies in APPSL mice: further value of this in vivo model of Alzheimer's disease. J Neuroinflammation. 2014;11:84 pubmed 出版商
Valero J, Mastrella G, Neiva I, S nchez S, Malva J. Long-term effects of an acute and systemic administration of LPS on adult neurogenesis and spatial memory. Front Neurosci. 2014;8:83 pubmed 出版商
Vacca V, Marinelli S, Pieroni L, Urbani A, Luvisetto S, Pavone F. Higher pain perception and lack of recovery from neuropathic pain in females: a behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice. Pain. 2014;155:388-402 pubmed 出版商
Nielsen G, Vorup Jensen T. Detection of soluble CR3 (CD11b/CD18) by time-resolved immunofluorometry. Methods Mol Biol. 2014;1100:355-64 pubmed 出版商
Orre M, Kamphuis W, Osborn L, Melief J, Kooijman L, Huitinga I, et al. Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice. Neurobiol Aging. 2014;35:1-14 pubmed 出版商
Harhausen D, Sudmann V, Khojasteh U, Müller J, Zille M, Graham K, et al. Specific imaging of inflammation with the 18 kDa translocator protein ligand DPA-714 in animal models of epilepsy and stroke. PLoS ONE. 2013;8:e69529 pubmed 出版商
Montalvo V, Quigley L, Vistica B, Boelte K, Nugent L, Takai T, et al. Environmental factors determine DAP12 deficiency to either enhance or suppress immunopathogenic processes. Immunology. 2013;140:475-82 pubmed 出版商
Bracchi Ricard V, Lambertsen K, Ricard J, Nathanson L, Karmally S, Johnstone J, et al. Inhibition of astroglial NF-?B enhances oligodendrogenesis following spinal cord injury. J Neuroinflammation. 2013;10:92 pubmed 出版商
Löffler T, Flunkert S, Havas D, Santha M, Hutter Paier B, Steyrer E, et al. Impact of ApoB-100 expression on cognition and brain pathology in wild-type and hAPPsl mice. Neurobiol Aging. 2013;34:2379-88 pubmed 出版商
Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer M, Heneka M. PPAR?/RXR?-induced and CD36-mediated microglial amyloid-? phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. J Neurosci. 2012;32:17321-31 pubmed 出版商
Siopi E, Llufriu Dabén G, Cho A, Vidal Lletjós S, Plotkine M, Marchand Leroux C, et al. Etazolate, an ?-secretase activator, reduces neuroinflammation and offers persistent neuroprotection following traumatic brain injury in mice. Neuropharmacology. 2013;67:183-92 pubmed 出版商
Yang J, Pattanayak A, Song M, Kou J, Taguchi H, Paul S, et al. Muscle-directed anti-A? single-chain antibody delivery via AAV1 reduces cerebral A? load in an Alzheimer's disease mouse model. J Mol Neurosci. 2013;49:277-88 pubmed 出版商
Ma W, Coon S, Zhao L, Fariss R, Wong W. A2E accumulation influences retinal microglial activation and complement regulation. Neurobiol Aging. 2013;34:943-60 pubmed 出版商
Flunkert S, Hierzer M, Löffler T, Rabl R, Neddens J, Duller S, et al. Elevated levels of soluble total and hyperphosphorylated tau result in early behavioral deficits and distinct changes in brain pathology in a new tau transgenic mouse model. Neurodegener Dis. 2013;11:194-205 pubmed 出版商
Heydenreich N, Nolte M, Göb E, Langhauser F, Hofmeister M, Kraft P, et al. C1-inhibitor protects from brain ischemia-reperfusion injury by combined antiinflammatory and antithrombotic mechanisms. Stroke. 2012;43:2457-67 pubmed 出版商
Liao H, Franck E, Freret M, Adriouch S, Baba Amer Y, Authier F, et al. Myoinjury transiently activates muscle antigen-specific CD8+ T cells in lymph nodes in a mouse model. Arthritis Rheum. 2012;64:3441-51 pubmed 出版商
Sato A, Ohtaki H, Tsumuraya T, Song D, Ohara K, Asano M, et al. Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury. J Neuroinflammation. 2012;9:65 pubmed 出版商
Sarkar J, Chaudhary S, Namavari A, Ozturk O, Chang J, Yco L, et al. Corneal neurotoxicity due to topical benzalkonium chloride. Invest Ophthalmol Vis Sci. 2012;53:1792-802 pubmed 出版商
Kou J, Song M, Pattanayak A, Lim J, Yang J, Cao D, et al. Combined treatment of A? immunization with statin in a mouse model of Alzheimer's disease. J Neuroimmunol. 2012;244:70-83 pubmed 出版商
Straccia M, Gresa Arribas N, Dentesano G, Ejarque Ortiz A, Tusell J, Serratosa J, et al. Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein ?. J Neuroinflammation. 2011;8:156 pubmed 出版商
Carta A, Frau L, Pisanu A, Wardas J, Spiga S, Carboni E. Rosiglitazone decreases peroxisome proliferator receptor-? levels in microglia and inhibits TNF-? production: new evidences on neuroprotection in a progressive Parkinson's disease model. Neuroscience. 2011;194:250-61 pubmed 出版商
Song M, Jin J, Lim J, Kou J, Pattanayak A, Rehman J, et al. TLR4 mutation reduces microglial activation, increases A? deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease. J Neuroinflammation. 2011;8:92 pubmed 出版商
Siopi E, Cho A, Homsi S, Croci N, Plotkine M, Marchand Leroux C, et al. Minocycline restores sAPP? levels and reduces the late histopathological consequences of traumatic brain injury in mice. J Neurotrauma. 2011;28:2135-43 pubmed 出版商
Zhao L, Ma W, Fariss R, Wong W. Minocycline attenuates photoreceptor degeneration in a mouse model of subretinal hemorrhage microglial: inhibition as a potential therapeutic strategy. Am J Pathol. 2011;179:1265-77 pubmed 出版商
Terwel D, Steffensen K, Verghese P, Kummer M, Gustafsson J, Holtzman D, et al. Critical role of astroglial apolipoprotein E and liver X receptor-? expression for microglial A? phagocytosis. J Neurosci. 2011;31:7049-59 pubmed 出版商
Füchtbauer L, Groth Rasmussen M, Holm T, Løbner M, Toft Hansen H, Khorooshi R, et al. Angiotensin II Type 1 receptor (AT1) signaling in astrocytes regulates synaptic degeneration-induced leukocyte entry to the central nervous system. Brain Behav Immun. 2011;25:897-904 pubmed 出版商
Hasegawa Ishii S, Takei S, Inaba M, Umegaki H, Chiba Y, Furukawa A, et al. Defects in cytokine-mediated neuroprotective glial responses to excitotoxic hippocampal injury in senescence-accelerated mouse. Brain Behav Immun. 2011;25:83-100 pubmed 出版商
Dohi K, Ohtaki H, Nakamachi T, Yofu S, Satoh K, Miyamoto K, et al. Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury. J Neuroinflammation. 2010;7:41 pubmed 出版商
Khorooshi R, Owens T. Injury-induced type I IFN signaling regulates inflammatory responses in the central nervous system. J Immunol. 2010;185:1258-64 pubmed 出版商
Gottfried Blackmore A, Sierra A, McEwen B, Ge R, Bulloch K. Microglia express functional 11 beta-hydroxysteroid dehydrogenase type 1. Glia. 2010;58:1257-66 pubmed 出版商
Heneka M, Nadrigny F, Regen T, Martinez Hernandez A, Dumitrescu Ozimek L, Terwel D, et al. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010;107:6058-63 pubmed 出版商
Homsi S, Piaggio T, Croci N, Noble F, Plotkine M, Marchand Leroux C, et al. Blockade of acute microglial activation by minocycline promotes neuroprotection and reduces locomotor hyperactivity after closed head injury in mice: a twelve-week follow-up study. J Neurotrauma. 2010;27:911-21 pubmed 出版商
Frontini A, Giordano A. Leptin-sensitive neurons in mouse preoptic area express alpha 1A- and alpha 2A-adrenergic receptor isoforms. Neurosci Lett. 2010;471:83-8 pubmed 出版商
Uceyler N, Göbel K, Meuth S, Ortler S, Stoll G, Sommer C, et al. Deficiency of the negative immune regulator B7-H1 enhances inflammation and neuropathic pain after chronic constriction injury of mouse sciatic nerve. Exp Neurol. 2010;222:153-60 pubmed 出版商
Makwana M, Werner A, Acosta Saltos A, Gonitel R, Pararajasingam A, Pararajasingham A, et al. Peripheral facial nerve axotomy in mice causes sprouting of motor axons into perineuronal central white matter: time course and molecular characterization. J Comp Neurol. 2010;518:699-721 pubmed 出版商
Santos A, Martín Oliva D, Ferrer Martín R, Tassi M, Calvente R, Sierra A, et al. Microglial response to light-induced photoreceptor degeneration in the mouse retina. J Comp Neurol. 2010;518:477-92 pubmed 出版商
Nielsen M, Lambertsen K, Clausen B, Meldgaard M, Diemer N, Zimmer J, et al. Nuclear translocation of endonuclease G in degenerating neurons after permanent middle cerebral artery occlusion in mice. Exp Brain Res. 2009;194:17-27 pubmed 出版商
Christensen J, Simonsen S, Fenger C, Sørensen M, Moos T, Christensen J, et al. Fulminant lymphocytic choriomeningitis virus-induced inflammation of the CNS involves a cytokine-chemokine-cytokine-chemokine cascade. J Immunol. 2009;182:1079-87 pubmed
Clausen B, Lambertsen K, Babcock A, Holm T, Dagnaes Hansen F, Finsen B. Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice. J Neuroinflammation. 2008;5:46 pubmed 出版商
Jin J, Kim H, Maxwell J, Li L, Fukuchi K. Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease. J Neuroinflammation. 2008;5:23 pubmed 出版商
Lehrmann E, Guidetti P, Love A, Williamson J, Bertram E, Schwarcz R. Glial activation precedes seizures and hippocampal neurodegeneration in measles virus-infected mice. Epilepsia. 2008;49 Suppl 2:13-23 pubmed 出版商
Kondo Y, Lemere C, Seabrook T. Osteopetrotic (op/op) mice have reduced microglia, no Abeta deposition, and no changes in dopaminergic neurons. J Neuroinflammation. 2007;4:31 pubmed
Herber D, Mercer M, Roth L, Symmonds K, Maloney J, Wilson N, et al. Microglial activation is required for Abeta clearance after intracranial injection of lipopolysaccharide in APP transgenic mice. J Neuroimmune Pharmacol. 2007;2:222-31 pubmed
Dissing Olesen L, Ladeby R, Nielsen H, Toft Hansen H, Dalmau I, Finsen B. Axonal lesion-induced microglial proliferation and microglial cluster formation in the mouse. Neuroscience. 2007;149:112-22 pubmed
He P, Zhong Z, Lindholm K, Berning L, Lee W, Lemere C, et al. Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice. J Cell Biol. 2007;178:829-41 pubmed
Sierra A, Gottfried Blackmore A, McEwen B, Bulloch K. Microglia derived from aging mice exhibit an altered inflammatory profile. Glia. 2007;55:412-24 pubmed
Kim Y, Choi D, Block M, Lorenzl S, Yang L, Kim Y, et al. A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation. FASEB J. 2007;21:179-87 pubmed
Mennini T, De Paola M, Bigini P, Mastrotto C, Fumagalli E, Barbera S, et al. Nonhematopoietic erythropoietin derivatives prevent motoneuron degeneration in vitro and in vivo. Mol Med. 2006;12:153-60 pubmed
Hsu J, McKeon R, Goussev S, Werb Z, Lee J, Trivedi A, et al. Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury. J Neurosci. 2006;26:9841-50 pubmed
Pedersen M, Minuzzi L, Wirenfeldt M, Meldgaard M, Slidsborg C, Cumming P, et al. Up-regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain. Eur J Neurosci. 2006;24:991-1000 pubmed
Fenger C, Drojdahl N, Wirenfeldt M, Sylvest L, Jorgensen O, Meldgaard M, et al. Tumor necrosis factor and its p55 and p75 receptors are not required for axonal lesion-induced microgliosis in mouse fascia dentata. Glia. 2006;54:591-605 pubmed
Kalinin S, Gavrilyuk V, Polak P, Vasser R, Zhao J, Heneka M, et al. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol Aging. 2007;28:1206-14 pubmed
Herber D, Maloney J, Roth L, Freeman M, Morgan D, Gordon M. Diverse microglial responses after intrahippocampal administration of lipopolysaccharide. Glia. 2006;53:382-91 pubmed
Heneka M, Sastre M, Dumitrescu Ozimek L, Dewachter I, Walter J, Klockgether T, et al. Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice. J Neuroinflammation. 2005;2:22 pubmed
Schütz B, Reimann J, Dumitrescu Ozimek L, Kappes Horn K, Landreth G, Schürmann B, et al. The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice. J Neurosci. 2005;25:7805-12 pubmed
Raptis S, Shapiro S, Simmons P, Cheng A, Pham C. Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering. Immunity. 2005;22:679-91 pubmed
Hebert G, Mingam R, Arsaut J, Dantzer R, Demotes Mainard J. Cellular distribution of interleukin-1alpha-immunoreactivity after MPTP intoxication in mice. Brain Res Mol Brain Res. 2005;138:156-63 pubmed
Ladeby R, Wirenfeldt M, Dalmau I, Gregersen R, Garcia Ovejero D, Babcock A, et al. Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury. Glia. 2005;50:121-31 pubmed
Engwerda C, Mynott T, Sawhney S, de Souza J, Bickle Q, Kaye P. Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria. J Exp Med. 2002;195:1371-7 pubmed
Carenini S, Maurer M, Werner A, Blazyca H, Toyka K, Schmid C, et al. The role of macrophages in demyelinating peripheral nervous system of mice heterozygously deficient in p0. J Cell Biol. 2001;152:301-8 pubmed
图像
图像 1 :
伯乐(Bio-Rad)公司 MCA711 图像 1
Figure A. Alexa Fluor 700 conjugated Rat anti Mouse GR-1 ( MCA2387A700 ) and Pacific Blue conjugated Rat IgG2b isotype control ( MCA6006PB ). Figure B. Alexa Fluor 700 conjugated Rat anti Mouse GR-1 ( MCA2387A700 ) and Pacific Blue conjugated Rat anti Mouse CD11b ( MCA711PB ). All experiments performed on red cell lysed mouse bone marrow gated on mononuclear cells in the presence of Mouse Seroblock ( BUF041A ). Data acquired on the ZE5 cell analyzer.
产品信息
Entity Type :
单克隆抗体
Entity Category :
抗体
产品代码 :
MCA711
描述 :
大鼠抗MOUSE CD11b
特异性 :
CD11b
靶物种 :
小鼠
宿主 :
大鼠
格式 :
纯化
Isotypes :
IgG2b
应用 :
C, 免疫沉淀, F, IF
应用类型 :
Immunofluorescence,Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen
交叉活性 :
人类
克隆 :
5C6
规格 :
1毫克
QuantityValue :
1
规格类型 :
毫克
GO登录号 :
GO:0045123, GO:0043395, GO:0030593, GO:0009897, GO:0050798, GO:0008201, GO:0007159, GO:0007229, GO:0008305, GO:0005634, GO:0001846, GO:0004872
GO条款 :
GO:0019041,receptor guanylate cyclase activity,viral antireceptor activity,laminin receptor protein,cell nucleus,leukocyte adhesion,leukocyte cell adhesion,integrin-mediated signalling pathway,heparan sulfate binding,juxtamembrane,outer surface of cytoplasmic membrane,heparin proteoglycan binding,immune cell cellular extravasation,leucocyte cellular extravasation,leukocyte cellular extravasation,transendothelial leukocyte migration,activated T lymphocyte proliferation,activated T-cell proliferation,activated T-lymphocyte proliferation,proliferation of activated T cells
UniProt数据库登录号 :
P05555
基因 :
Itgam
基因ID_URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=16409
出版同义词 :
整合素甲M链, MAC-1
Entity Formats :
ALEXA FLUOR® 647,ALEXA FLUOR® 700,Amethyst Blue,Amethyst Orange,FITC,Low Endotoxin,Pacific Blue®,Preservative Free,Purified,RPE,RPE-ALEXA FLUOR® 647,RPE-ALEXA FLUOR® 750,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 700,StarBright Blue 765,StarBright Blue 810,StarBright UltraViolet 400,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright UltraViolet 665,StarBright UltraViolet 740,StarBright UltraViolet 795,StarBright Violet 440,StarBright Violet 475,StarBright Violet 515,StarBright Violet 570,StarBright Violet 610,StarBright Violet 670,StarBright Violet 710,StarBright Violet 760,StarBright Violet 790,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 720,StarBright Yellow 800
UNSPSC :
41116161
浓度 :
IgG浓度1毫克/毫升
产品形式 :
纯化IgG-液体
Primary Secondary :
Primary
英镑价格 :
415
欧元价格 :
581
美元价格 :
581美元
价格CHF :
632
价格SEK :
6107
价格NOK :
6225
价格DKK :
4332
更多信息或购买 :
公司信息
伯乐(Bio-Rad)公司
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
44-1865-852-700
公司总部: 英国
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