产品简要
公司名称 :
伯乐（Bio-Rad）公司
其他品牌 :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
产品类型 :
抗体
产品名称 :
大鼠抗MOUSE CD11b
目录 :
MCA711G
规格 :
0.25毫克
价格 :
372美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
5C6
反应物种 :
小鼠
应用 :
免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
更多信息或购买 :
伯乐（Bio-Rad）公司 产品网页
文章摘录数: 34
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:15,000; 图 1j, 3b-d, 4e
Zhao Z, Wang Y, Zhou R, Li Y, Gao Y, Tu D, et al. A novel role of NLRP3-generated IL-1β in the acute-chronic transition of peripheral lipopolysaccharide-elicited neuroinflammation: implications for sepsis-associated neurodegeneration. J Neuroinflammation. 2020;17:64 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:10,000; 图 4a
Gao Y, Tu D, Yang R, Chu C, Hong J, Gao H. Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1β Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration. Int J Mol Sci. 2020;21: pubmed 出版商
  • 免疫组化; 小鼠; 图 3b
Thygesen C, Ilkjær L, Kempf S, Hemdrup A, von Linstow C, Babcock A, et al. Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1ΔE9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease. Front Cell Neurosci. 2018;12:397 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:300; 图 3c
Pulido Salgado M, Vidal Taboada J, Garcia Díaz Barriga G, Serratosa J, Valente T, Castillo P, et al. Myeloid C/EBP? deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2017;14:54 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:250; 图 1c
Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 5a
Koyanagi S, Kusunose N, Taniguchi M, Akamine T, Kanado Y, Ozono Y, et al. Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia. Nat Commun. 2016;7:13102 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 4
McGonigal R, Cunningham M, Yao D, Barrie J, Sankaranarayanan S, Fewou S, et al. C1q-targeted inhibition of the classical complement pathway prevents injury in a novel mouse model of acute motor axonal neuropathy. Acta Neuropathol Commun. 2016;4:23 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2
Chen H, Sun Y, Lai L, Wu H, Xiao Y, Ming B, et al. Interleukin-33 is released in spinal cord and suppresses experimental autoimmune encephalomyelitis in mice. Neuroscience. 2015;308:157-68 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Kan M, Lee J, Wilson J, Everhart A, Brown C, Hoofnagle A, et al. Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. J Neurosci. 2015;35:5969-82 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 2
Tyzack G, Sitnikov S, Barson D, Adams Carr K, Lau N, Kwok J, et al. Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression. Nat Commun. 2014;5:4294 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
Ding Y, Qu Y, Feng J, Wang M, Han Q, So K, et al. Functional motor recovery from motoneuron axotomy is compromised in mice with defective corticospinal projections. PLoS ONE. 2014;9:e101918 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 s10a
Paez Gonzalez P, Asrican B, Rodriguez E, Kuo C. Identification of distinct ChAT? neurons and activity-dependent control of postnatal SVZ neurogenesis. Nat Neurosci. 2014;17:934-42 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫组化; 小鼠
de Waard M, van der Pluijm I, Zuiderveen Borgesius N, Comley L, Haasdijk E, Rijksen Y, et al. Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice. Acta Neuropathol. 2010;120:461-75 pubmed 出版商
Bussian T, Aziz A, Meyer C, Swenson B, van Deursen J, Baker D. Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline. Nature. 2018;562:578-582 pubmed 出版商
Soto M, Herzog C, Pacheco J, Fujisaka S, Bullock K, Clish C, et al. Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism. Mol Psychiatry. 2018;23:2287-2301 pubmed 出版商
Zheng J, Jia L, Mori S, Kodama T. Evaluation of metastatic niches in distant organs after surgical removal of tumor-bearing lymph nodes. BMC Cancer. 2018;18:608 pubmed 出版商
Wang D, Tawfik V, Corder G, Low S, Francois A, Basbaum A, et al. Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits. Neuron. 2018;98:90-108.e5 pubmed 出版商
Renault Mihara F, Mukaino M, Shinozaki M, Kumamaru H, Kawase S, Baudoux M, et al. Regulation of RhoA by STAT3 coordinates glial scar formation. J Cell Biol. 2017;216:2533-2550 pubmed 出版商
Quattromani M, Cordeau P, Ruscher K, Kriz J, Wieloch T. Enriched housing down-regulates the Toll-like receptor 2 response in the mouse brain after experimental stroke. Neurobiol Dis. 2014;66:66-73 pubmed 出版商
Straccia M, Dentesano G, Valente T, Pulido Salgado M, Solà C, Saura J. CCAAT/enhancer binding protein ? regulates prostaglandin E synthase expression and prostaglandin E2 production in activated microglial cells. Glia. 2013;61:1607-19 pubmed 出版商
Leijon J, Carlsson F, Brannstrom J, Sanchez J, Larsson R, Nilsson B, et al. Attachment of flexible heparin chains to gelatin scaffolds improves endothelial cell infiltration. Tissue Eng Part A. 2013;19:1336-48 pubmed 出版商
Chao Y, Karmali P, Simberg D. Role of carbohydrate receptors in the macrophage uptake of dextran-coated iron oxide nanoparticles. Adv Exp Med Biol. 2012;733:115-23 pubmed 出版商
Straccia M, Gresa Arribas N, Dentesano G, Ejarque Ortiz A, Tusell J, Serratosa J, et al. Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein ?. J Neuroinflammation. 2011;8:156 pubmed 出版商
Wu T, Wu H, Wang J, Wang J. Expression and cellular localization of cyclooxygenases and prostaglandin E synthases in the hemorrhagic brain. J Neuroinflammation. 2011;8:22 pubmed 出版商
Yang Y, Tian S, Wu L, Huang D, Wu W. Fibrinogen depleting agent batroxobin has a beneficial effect on experimental autoimmune encephalomyelitis. Cell Mol Neurobiol. 2011;31:437-48 pubmed 出版商
Dohi K, Ohtaki H, Nakamachi T, Yofu S, Satoh K, Miyamoto K, et al. Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury. J Neuroinflammation. 2010;7:41 pubmed 出版商
Santos A, Martín Oliva D, Ferrer Martín R, Tassi M, Calvente R, Sierra A, et al. Microglial response to light-induced photoreceptor degeneration in the mouse retina. J Comp Neurol. 2010;518:477-92 pubmed 出版商
Paulussen M, Landuyt B, Schoofs L, Luyten W, Arckens L. Thymosin beta 4 mRNA and peptide expression in phagocytic cells of different mouse tissues. Peptides. 2009;30:1822-32 pubmed 出版商
Devey L, Ferenbach D, Mohr E, Sangster K, Bellamy C, Hughes J, et al. Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism. Mol Ther. 2009;17:65-72 pubmed 出版商
Tusell J, Ejarque Ortiz A, Mancera P, Solà C, Saura J, Serratosa J. Upregulation of p21Cip1 in activated glial cells. Glia. 2009;57:524-34 pubmed 出版商
Niciu M, Ma X, El Meskini R, Pachter J, Mains R, Eipper B. Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease. Neurobiol Dis. 2007;27:278-91 pubmed
Ejarque Ortiz A, Medina M, Tusell J, Perez Gonzalez A, Serratosa J, Saura J. Upregulation of CCAAT/enhancer binding protein beta in activated astrocytes and microglia. Glia. 2007;55:178-88 pubmed
Engwerda C, Mynott T, Sawhney S, de Souza J, Bickle Q, Kaye P. Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria. J Exp Med. 2002;195:1371-7 pubmed
Carenini S, Maurer M, Werner A, Blazyca H, Toyka K, Schmid C, et al. The role of macrophages in demyelinating peripheral nervous system of mice heterozygously deficient in p0. J Cell Biol. 2001;152:301-8 pubmed
图像
图像 1 :
伯乐（Bio-Rad）公司 MCA711G 图像 1
Figure A. Alexa Fluor 700 conjugated Rat anti Mouse GR-1 ( MCA2387A700 ) and Pacific Blue conjugated Rat IgG2b isotype control ( MCA6006PB ). Figure B. Alexa Fluor 700 conjugated Rat anti Mouse GR-1 ( MCA2387A700 ) and Pacific Blue conjugated Rat anti Mouse CD11b ( MCA711PB ). All experiments performed on red cell lysed mouse bone marrow gated on mononuclear cells in the presence of Mouse Seroblock ( BUF041A ). Data acquired on the ZE5 cell analyzer.
产品信息
Entity Type :
单克隆抗体
Entity Category :
抗体
ProductCode :
MCA711G
描述 :
大鼠抗MOUSE CD11b
特异性 :
CD11b
目标物种 :
小鼠
宿主 :
大鼠
格式 :
纯化
Isotypes :
IgG2b
应用 :
F, IF, C, 免疫沉淀
ApplicationTypes :
Immunohistology - Frozen,Immunofluorescence,Flow Cytometry,Immunoprecipitation
交叉活性 :
人类
克隆 :
5C6
规格 :
0.25毫克
Quantity Value :
0.25
规格类型 :
毫克
GO登录号 :
GO:0004872, GO:0001846, GO:0008305, GO:0005634, GO:0007229, GO:0007159, GO:0008201, GO:0030593, GO:0009897, GO:0050798, GO:0045123, GO:0043395
GOTerms :
GO:0019041,receptor guanylate cyclase activity,viral antireceptor activity,laminin receptor protein,cell nucleus,leukocyte adhesion,leukocyte cell adhesion,integrin-mediated signalling pathway,heparan sulfate binding,juxtamembrane,outer surface of cytoplasmic membrane,heparin proteoglycan binding,immune cell cellular extravasation,leucocyte cellular extravasation,leukocyte cellular extravasation,transendothelial leukocyte migration,activated T lymphocyte proliferation,activated T-cell proliferation,activated T-lymphocyte proliferation,proliferation of activated T cells
UniProt数据库登录号 :
P05555
基因 :
Itgam
GeneID网址 :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=16409
出版同义词 :
整合素甲M链, MAC-1
Entity Formats :
ALEXA FLUOR® 647,ALEXA FLUOR® 700,Amethyst Blue,Amethyst Orange,FITC,Low Endotoxin,Pacific Blue®,Preservative Free,Purified,RPE,RPE-ALEXA FLUOR® 647,RPE-ALEXA FLUOR® 750,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 700,StarBright Blue 765,StarBright Blue 810,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815,StarBright UltraViolet 400,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright UltraViolet 665,StarBright UltraViolet 740,StarBright UltraViolet 795,StarBright Violet 440,StarBright Violet 475,StarBright Violet 515,StarBright Violet 570,StarBright Violet 610,StarBright Violet 670,StarBright Violet 710,StarBright Violet 760,StarBright Violet 790,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 720,StarBright Yellow 800
UNSPSC :
41116161
浓度 :
IgG浓度1毫克/毫升
产品形式 :
纯化IgG-液体
PriceGBP :
266
PriceEUR :
372
PriceUSD :
372美元
PriceCHF :
405
PriceSEK :
4055
PriceNOK :
4075
PriceDKK :
2774
更多信息或购买 :
伯乐（Bio-Rad）公司 产品网页
公司信息
伯乐（Bio-Rad）公司
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
44-1865-852-700
公司总部: 英国
伯乐（Bio-Rad）公司是世界领先的抗体生产商之一。通过其原名为AbD Serotec公司的专业抗体业务团队，提供超过12,000种抗体及相关试剂，专注于免疫学、肿瘤、兽医研究及细胞生物学等领域。
抗体产品包括细胞凋亡试剂盒，自噬检测试剂，CD分子标记物，标签抗体，免疫学研究抗体，神经科学研究抗体和兽医应用试剂等。
伯乐（Bio-Rad）公司在英国拥有经ISO9001和ISO13485认证的生产厂房，同时在德国和美国均设有经ISO9001认证的厂房。
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