产品简要
公司名称 :
伯乐(Bio-Rad)公司
其他品牌 :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
产品类型 :
抗体
产品名称 :
大鼠抗微管蛋白甲
目录 :
MCA78G
规格 :
0.5毫克
价格 :
493美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
YOL1/34
反应物种 :
酵母菌目, 人类, 小鼠, 大鼠, brewer's yeast, roundworm
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 70
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:1000; 图 1d
  • 免疫细胞化学; 小鼠; 1:1000; 图 1f
Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand A, Robertson D, et al. RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol Cell. 2019;73:413-428.e7 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
  • 免疫细胞化学; roundworm ; 图 2
Wike C, Graves H, Hawkins R, Gibson M, Ferdinand M, Zhang T, et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. elife. 2016;5:e11402 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:1000; 图 3
  • 免疫印迹; 大鼠; 1:1000
Uehara R, Kamasaki T, Hiruma S, Poser I, Yoda K, Yajima J, et al. Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission. Mol Biol Cell. 2016;27:812-27 pubmed 出版商
  • 免疫细胞化学; 人类; 1:3000
Zielinska A, Holubcová Z, Blayney M, Elder K, Schuh M. Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect. elife. 2015;4:e11389 pubmed 出版商
  • 免疫组化; 小鼠; 1:3000; 图 s2
Clift D, Schuh M. A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes. Nat Commun. 2015;6:7217 pubmed 出版商
  • 免疫细胞化学; 酵母菌目
Tsai F, Vijayraghavan S, Prinz J, MacAlpine H, MacAlpine D, Schwacha A. Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate. Mol Cell Biol. 2015;35:2131-43 pubmed 出版商
  • 流式细胞仪; brewer's yeast; 图 s3
Iacovella M, Golfieri C, Massari L, Busnelli S, Pagliuca C, Dal Maschio M, et al. Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation. Nat Commun. 2015;6:6643 pubmed 出版商
  • 免疫印迹; brewer's yeast; 图 s1
Sánchez de Groot N, Gomes R, Villar Piqué A, Babu M, Coelho A, Ventura S. Proteome response at the edge of protein aggregation. Open Biol. 2015;5:140221 pubmed 出版商
  • 免疫细胞化学; 人类
Hasegawa H, Ishibashi K, Kubota S, Yamaguchi C, Yuki R, Nakajo H, et al. Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase. PLoS ONE. 2014;9:e116048 pubmed 出版商
  • 免疫细胞化学; 人类
Sarbajna S, Davies D, West S. Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe. Genes Dev. 2014;28:1124-36 pubmed 出版商
  • 免疫印迹; 人类
Bersten D, Bruning J, Peet D, Whitelaw M. Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function. PLoS ONE. 2014;9:e85768 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
Kubota S, Fukumoto Y, Aoyama K, Ishibashi K, Yuki R, Morinaga T, et al. Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1? (HP1?) with heterochromatin. J Biol Chem. 2013;288:17871-83 pubmed 出版商
Scheffler K, Uraji J, Jentoft I, Cavazza T, Mönnich E, Mogessie B, et al. Two mechanisms drive pronuclear migration in mouse zygotes. Nat Commun. 2021;12:841 pubmed 出版商
Zielinska A, Bellou E, Sharma N, Frombach A, Seres K, Gruhn J, et al. Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs. Curr Biol. 2019;29:3749-3765.e7 pubmed 出版商
Adamakis I, Panteris E, Eleftheriou E. Tubulin Acetylation Mediates Bisphenol A Effects on the Microtubule Arrays of Allium cepa and Triticum turgidum. Biomolecules. 2019;9: pubmed 出版商
Karasu M, Bouftas N, Keeney S, Wassmann K. Cyclin B3 promotes anaphase I onset in oocyte meiosis. J Cell Biol. 2019;218:1265-1281 pubmed 出版商
Sawyer E, Joshi P, Jorgensen V, Yunus J, Berchowitz L, Unal E. Developmental regulation of an organelle tether coordinates mitochondrial remodeling in meiosis. J Cell Biol. 2019;218:559-579 pubmed 出版商
Fink S, Zugelder L, Roth B, Brandt E, Meloche S, Izsvák Z, et al. A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors. PLoS ONE. 2018;13:e0205585 pubmed 出版商
Yamamoto Hino M, Katsumata E, Suzuki E, Maeda Y, Kinoshita T, Goto S. Nuclear envelope localization of PIG-B is essential for GPI-anchor synthesis in Drosophila. J Cell Sci. 2018;131: pubmed 出版商
Horiuchi M, Kuga T, Saito Y, Nagano M, Adachi J, Tomonaga T, et al. The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1. J Biol Chem. 2018;293:15524-15537 pubmed 出版商
Balmus G, Larrieu D, Barros A, Collins C, Abrudan M, Demir M, et al. Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome. Nat Commun. 2018;9:1700 pubmed 出版商
Parker F, Batchelor M, Wolny M, Hughes R, Knight P, Peckham M. A1603P and K1617del, Mutations in β-Cardiac Myosin Heavy Chain that Cause Laing Early-Onset Distal Myopathy, Affect Secondary Structure and Filament Formation In Vitro and In Vivo. J Mol Biol. 2018;430:1459-1478 pubmed 出版商
Wang S, Stoops E, Cp U, Markus B, Reuveny A, Ordan E, et al. Mechanotransduction via the LINC complex regulates DNA replication in myonuclei. J Cell Biol. 2018;217:2005-2018 pubmed 出版商
Touati S, Kataria M, Jones A, Snijders A, Uhlmann F. Phosphoproteome dynamics during mitotic exit in budding yeast. EMBO J. 2018;37: pubmed 出版商
Novák D, Vadovic P, Ovecka M, Samajová O, Komis G, Colcombet J, et al. Gene Expression Pattern and Protein Localization of Arabidopsis Phospholipase D Alpha 1 Revealed by Advanced Light-Sheet and Super-Resolution Microscopy. Front Plant Sci. 2018;9:371 pubmed 出版商
Veri A, Miao Z, Shapiro R, Tebbji F, O Meara T, Kim S, et al. Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space. PLoS Genet. 2018;14:e1007270 pubmed 出版商
Murayama Y, Samora C, Kurokawa Y, Iwasaki H, Uhlmann F. Establishment of DNA-DNA Interactions by the Cohesin Ring. Cell. 2018;172:465-477.e15 pubmed 出版商
Vaškebová L, Samaj J, Ovecka M. Single-point ACT2 gene mutation in the Arabidopsis root hair mutant der1-3 affects overall actin organization, root growth and plant development. Ann Bot. 2018;122:889-901 pubmed 出版商
Clift D, McEwan W, Labzin L, Konieczny V, Mogessie B, James L, et al. A Method for the Acute and Rapid Degradation of Endogenous Proteins. Cell. 2017;171:1692-1706.e18 pubmed 出版商
Tungadi E, Ito A, Kiyomitsu T, Goshima G. Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2. J Cell Sci. 2017;130:3676-3684 pubmed 出版商
Carvalhal S, Stevense M, Koehler K, Naumann R, Huebner A, Jessberger R, et al. ALADIN is required for the production of fertile mouse oocytes. Mol Biol Cell. 2017;28:2470-2478 pubmed 出版商
Herwald S, Zucchi P, Tan S, Kumamoto C. The two transmembrane regions of Candida albicans Dfi1 contribute to its biogenesis. Biochem Biophys Res Commun. 2017;488:153-158 pubmed 出版商
Lucchetta E, Ohlstein B. Amitosis of Polyploid Cells Regenerates Functional Stem Cells in the Drosophila Intestine. Cell Stem Cell. 2017;20:609-620.e6 pubmed 出版商
Morii M, Kubota S, Honda T, Yuki R, Morinaga T, Kuga T, et al. Src Acts as an Effector for Ku70-dependent Suppression of Apoptosis through Phosphorylation of Ku70 at Tyr-530. J Biol Chem. 2017;292:1648-1665 pubmed 出版商
Chen C, Lim H, Shi J, Tamura S, Maeshima K, Surana U, et al. Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo. Mol Biol Cell. 2016;27:3357-3368 pubmed
Baumann J, Wong J, Sun Y, Conklin D. Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells. BMC Cancer. 2016;16:551 pubmed 出版商
O Meara T, Veri A, Polvi E, Li X, Valaei S, Diezmann S, et al. Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress. PLoS Genet. 2016;12:e1006142 pubmed 出版商
Bersten D, Sullivan A, Li D, Bhakti V, Bent S, Whitelaw M. Inducible and reversible lentiviral and Recombination Mediated Cassette Exchange (RMCE) systems for controlling gene expression. PLoS ONE. 2015;10:e0116373 pubmed 出版商
Tape C, Norrie I, Worboys J, Lim L, Lauffenburger D, Jørgensen C. Cell-specific labeling enzymes for analysis of cell-cell communication in continuous co-culture. Mol Cell Proteomics. 2014;13:1866-76 pubmed 出版商
Sullivan A, Raimondo A, Schwab T, Bruning J, Froguel P, Farooqi I, et al. Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2. Biochem J. 2014;461:403-12 pubmed 出版商
Nakayama Y, Saito Y, Soeda S, Iwamoto E, Ogawa S, Yamagishi N, et al. Genistein induces cytokinesis failure through RhoA delocalization and anaphase chromosome bridging. J Cell Biochem. 2014;115:763-71 pubmed 出版商
Hammond S, Byrum S, Namjoshi S, Graves H, Dennehey B, Tackett A, et al. Mitotic phosphorylation of histone H3 threonine 80. Cell Cycle. 2014;13:440-52 pubmed 出版商
Aoyama K, Yuki R, Horiike Y, Kubota S, Yamaguchi N, Morii M, et al. Formation of long and winding nuclear F-actin bundles by nuclear c-Abl tyrosine kinase. Exp Cell Res. 2013;319:3251-68 pubmed 出版商
Zhang A, Liu Z, Myers L. Differential regulation of white-opaque switching by individual subunits of Candida albicans mediator. Eukaryot Cell. 2013;12:1293-304 pubmed 出版商
Ramachandrappa S, Raimondo A, Cali A, Keogh J, Henning E, Saeed S, et al. Rare variants in single-minded 1 (SIM1) are associated with severe obesity. J Clin Invest. 2013;123:3042-50 pubmed 出版商
Hao N, Bhakti V, Peet D, Whitelaw M. Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation. Nucleic Acids Res. 2013;41:5626-38 pubmed 出版商
Soeda S, Nakayama Y, Honda T, Aoki A, Tamura N, Abe K, et al. v-Src causes delocalization of Mklp1, Aurora B, and INCENP from the spindle midzone during cytokinesis failure. Exp Cell Res. 2013;319:1382-97 pubmed 出版商
Bürstenbinder K, Savchenko T, Muller J, Adamson A, Stamm G, Kwong R, et al. Arabidopsis calmodulin-binding protein IQ67-domain 1 localizes to microtubules and interacts with kinesin light chain-related protein-1. J Biol Chem. 2013;288:1871-82 pubmed 出版商
Robbins N, Leach M, Cowen L. Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance. Cell Rep. 2012;2:878-88 pubmed 出版商
González Santamaría J, Campagna M, Ortega Molina A, Marcos Villar L, de la Cruz Herrera C, Gonzalez D, et al. Regulation of the tumor suppressor PTEN by SUMO. Cell Death Dis. 2012;3:e393 pubmed 出版商
Hao N, Lee K, Furness S, Bosdotter C, Poellinger L, Whitelaw M. Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling. Mol Pharmacol. 2012;82:1082-93 pubmed 出版商
Nakayama Y, Matsui Y, Takeda Y, Okamoto M, Abe K, Fukumoto Y, et al. c-Src but not Fyn promotes proper spindle orientation in early prometaphase. J Biol Chem. 2012;287:24905-15 pubmed 出版商
Walsh C. The structure of the mitotic spindle and nucleolus during mitosis in the amebo-flagellate Naegleria. PLoS ONE. 2012;7:e34763 pubmed 出版商
Sato H, Yamada R, Yanagihara M, Okuzawa H, Iwata H, Kurosawa A, et al. New 2-aryl-1,4-naphthoquinone-1-oxime methyl ether compound induces microtubule depolymerization and subsequent apoptosis. J Pharmacol Sci. 2012;118:467-78 pubmed
Aoyama K, Fukumoto Y, Ishibashi K, Kubota S, Morinaga T, Horiike Y, et al. Nuclear c-Abl-mediated tyrosine phosphorylation induces chromatin structural changes through histone modifications that include H4K16 hypoacetylation. Exp Cell Res. 2011;317:2874-903 pubmed 出版商
Robbins N, Uppuluri P, Nett J, Rajendran R, Ramage G, Lopez Ribot J, et al. Hsp90 governs dispersion and drug resistance of fungal biofilms. PLoS Pathog. 2011;7:e1002257 pubmed 出版商
Keeling J, Miller R. Indirect immunofluorescence for monitoring spindle assembly and disassembly in yeast. Methods Mol Biol. 2011;782:231-44 pubmed 出版商
Hao N, Whitelaw M, Shearwin K, Dodd I, Chapman Smith A. Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR. Nucleic Acids Res. 2011;39:3695-709 pubmed 出版商
To S, Rodda S, Rathjen P, Keough R. Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation. PLoS ONE. 2010;5:e11702 pubmed 出版商
Whelan F, Hao N, Furness S, Whitelaw M, Chapman Smith A. Amino acid substitutions in the aryl hydrocarbon receptor ligand binding domain reveal YH439 as an atypical AhR activator. Mol Pharmacol. 2010;77:1037-46 pubmed 出版商
Higashiyama Y, Takahashi A, Fukumoto Y, Nakayama Y, Yamaguchi N. Induction of chromatin condensation by nuclear expression of a novel arginine-rich cationic protein genetically engineered from the enhanced green fluorescent protein. Cytotechnology. 2009;60:153-9 pubmed 出版商
Sdralia N, Patmanidi A, Velentzas A, Margaritis L, Baltatzis G, Hatzinikolaou D, et al. The mode of lymphoblastoid cell death in response to gas phase cigarette smoke is dose-dependent. Respir Res. 2009;10:82 pubmed 出版商
Nakayama Y, Igarashi A, Kikuchi I, Obata Y, Fukumoto Y, Yamaguchi N. Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway. Exp Cell Res. 2009;315:2515-28 pubmed 出版商
Hartl T, Sweeney S, Knepler P, Bosco G. Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosis. PLoS Genet. 2008;4:e1000228 pubmed 出版商
Kuga T, Hoshino M, Nakayama Y, Kasahara K, Ikeda K, Obata Y, et al. Role of Src-family kinases in formation of the cortical actin cap at the dorsal cell surface. Exp Cell Res. 2008;314:2040-54 pubmed 出版商
Kuga T, Nakayama Y, Hoshino M, Higashiyama Y, Obata Y, Matsuda D, et al. Differential mitotic activation of endogenous c-Src, c-Yes, and Lyn in HeLa cells. Arch Biochem Biophys. 2007;466:116-24 pubmed
Yu H, Koshland D. The Aurora kinase Ipl1 maintains the centromeric localization of PP2A to protect cohesin during meiosis. J Cell Biol. 2007;176:911-8 pubmed
Kateneva A, Konovchenko A, Guacci V, Dresser M. Recombination protein Tid1p controls resolution of cohesin-dependent linkages in meiosis in Saccharomyces cerevisiae. J Cell Biol. 2005;171:241-53 pubmed
White J, Stead E, Faast R, Conn S, Cartwright P, Dalton S. Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation. Mol Biol Cell. 2005;16:2018-27 pubmed
Lavoie B, Hogan E, Koshland D. In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin. J Cell Biol. 2002;156:805-15 pubmed
图像
图像 1 :
伯乐(Bio-Rad)公司 MCA78G 图像 1
Published customer image: . Rat anti tubulin alpha antibody, clone YOL1/34 ( MCA78G ) used as a loading control for the detection of tubulin- in Candida albicans lysates by western blotting. Image caption: . Staurosporine induces filamentation independent of Nrg1 degradation. (A) Staurosporine-induced filamentation is not accompanied by Nrg1 protein degradation. SN95 wild-type cells expressing native levels of HA-tagged Nrg1 were grown in YPD plus 10% serum at 37 C, YPD plus 200 mM hydroxyurea (HU) at 30 C, or YPD plus 0.5 ug/ml staurosporine at 30 C for 5 or 65 min. Total proteins were resolved by SDS-PAGE gel, and the blot was hybridized with anti-HA to detect Nrg1 and anti-tubulin to monitor tubulin as a loading control. (B) Staurosporine induces germ tube formation at different kinetics from serum and hydroxyurea. Cells were imaged by DIC microscopy. The scale bar indicates 10 um. From: Xie JL, O'Meara TR, Polvi EJ, Robbins N, Cowen LE. Staurosporine Induces Filamentation in the Human Fungal Pathogen Candida albicans via Signaling through Cyr1 and Protein Kinase A. mSphere. 2017 Mar 1;2(2). pii: e00056-17. eCollection 2017 Mar-Apr .
产品信息
Entity Type :
单克隆抗体
Entity Category :
抗体
产品代码 :
MCA78G
描述 :
大鼠抗微管蛋白甲
特异性 :
微管蛋白甲
靶物种 :
酵母
宿主 :
大鼠
格式 :
纯化
Isotypes :
IgG2a
应用 :
免疫印迹, R, IF, C, E
应用类型 :
Western Blotting,Immunofluorescence,Immunohistology - Frozen,ELISA,Radioimmunoassays
交叉活性 :
Fungal,Drosophila,Asplenium nidus,Ashbya,Arabidopsis thaliana,Birds,Mammals,Human,Mouse,Seagrass (Cymodocea nodosa),Saccharomyces,Platyzoma ,Naegleria
克隆 :
YOL1/34
规格 :
0.5毫克
QuantityValue :
0.5
规格类型 :
毫克
Entity Formats :
纯化
UNSPSC :
41116161
浓度 :
IgG浓度1.0毫克/毫升
产品形式 :
纯化IgG-液体
Primary Secondary :
Primary
英镑价格 :
352
欧元价格 :
493
美元价格 :
493美元
价格CHF :
536
价格SEK :
5182
价格NOK :
5282
价格DKK :
3676
更多信息或购买 :
公司信息
伯乐(Bio-Rad)公司
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
44-1865-852-700
公司总部: 英国
伯乐(Bio-Rad)公司是世界领先的抗体生产商之一。通过其原名为AbD Serotec公司的专业抗体业务团队,提供超过12,000种抗体及相关试剂,专注于免疫学、肿瘤、兽医研究及细胞生物学等领域。
抗体产品包括细胞凋亡试剂盒,自噬检测试剂,CD分子标记物,标签抗体,免疫学研究抗体,神经科学研究抗体和兽医应用试剂等。
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