产品简要
公司名称 :
Bio X Cell
产品类型 :
抗体
产品名称 :
InVivoMAb抗小鼠NK1.1
目录 :
BE0036-100毫克
规格 :
100毫克
价格 :
2, 782.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
PK136
反应物种 :
小鼠
应用 :
流式细胞仪, 抑制或激活实验, 其他
更多信息或购买 :
文章摘录数: 69
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 小鼠; ; 图 2d
Aiken T, Erbe A, Zebertavage L, Komjathy D, Feils A, Rodriguez M, et al. Mechanism of effective combination radio-immunotherapy against 9464D-GD2, an immunologically cold murine neuroblastoma. J Immunother Cancer. 2022;10: pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4a
Meléndez E, Chondronasiou D, Mosteiro L, Mart xed nez de Villarreal J, Fern xe1 ndez Alfara M, Lynch C, et al. Natural killer cells act as an extrinsic barrier for in vivo reprogramming. Development. 2022;149: pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 3a
Li S, Dou B, Shu S, Wei L, Zhu S, Ke Z, et al. Suppressing NK Cells by Astragaloside IV Protects Against Acute Ischemic Stroke in Mice Via Inhibiting STAT3. Front Pharmacol. 2021;12:802047 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 s5a
Petley E, Koay H, Henderson M, Sek K, Todd K, Keam S, et al. MAIT cells regulate NK cell-mediated tumor immunity. Nat Commun. 2021;12:4746 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Zhou T, Damsky W, Weizman O, McGeary M, Hartmann K, Rosen C, et al. IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy. Nature. 2020;583:609-614 pubmed 出版商
  • 其他; 小鼠
Koprivsek J, He Y, Song C, Zhang N, Tumanov A, Zhong G. Evasion of Innate Lymphoid Cell-Regulated Gamma Interferon Responses by Chlamydia muridarum To Achieve Long-Lasting Colonization in Mouse Colon. Infect Immun. 2020;88: pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 s8
  • 流式细胞仪; 小鼠; 图 s5e
Ruscetti M, Leibold J, Bott M, Fennell M, Kulick A, Salgado N, et al. NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science. 2018;362:1416-1422 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 2c
Sato Y, Bolzenius J, Eteleeb A, Su X, Maher C, Sehn J, et al. CD4+ T cells induce rejection of urothelial tumors after immune checkpoint blockade. JCI Insight. 2018;3: pubmed 出版商
  • 其他; 小鼠; 图 2f
Ferrari de Andrade L, Tay R, Pan D, Luoma A, Ito Y, Badrinath S, et al. Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity. Science. 2018;359:1537-1542 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 6b
Kwan B, Zhu E, Tzeng A, Sugito H, Eltahir A, Ma B, et al. Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses. J Exp Med. 2017;214:1679-1690 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 3g
Stacey M, Clare S, Clement M, Marsden M, Abdul Karim J, Kane L, et al. The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis. J Clin Invest. 2017;127:1463-1474 pubmed 出版商
Wu M, Xia X, Hu J, Fowlkes N, Li S. WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression. Nat Commun. 2021;12:3500 pubmed 出版商
Mahr B, Pilat N, Granofszky N, Muckenhuber M, Unger L, Weijler A, et al. Distinct roles for major and minor antigen barriers in chimerism-based tolerance under irradiation-free conditions. Am J Transplant. 2021;21:968-977 pubmed 出版商
Oba T, Long M, Keler T, Marsh H, Minderman H, Abrams S, et al. Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s. Nat Commun. 2020;11:5415 pubmed 出版商
Swaminathan S, Hansen A, Heftdal L, Dhanasekaran R, Deutzmann A, Fernandez W, et al. MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies. Nat Commun. 2020;11:2860 pubmed 出版商
Williams J, Li S, Higgs E, Cabanov A, Wang X, Huang H, et al. Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-γ-signaling mutant cancer cells. Nat Commun. 2020;11:602 pubmed 出版商
Abulizi A, Shao Y, Aji T, Li Z, Zhang C, Aini A, et al. Echinococcus multilocularis inoculation induces NK cell functional decrease through high expression of NKG2A in C57BL/6 mice. BMC Infect Dis. 2019;19:792 pubmed 出版商
Westrich J, Vermeer D, Silva A, Bonney S, Berger J, Cicchini L, et al. CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression. Oncogene. 2019;: pubmed 出版商
Engelbertsen D, Autio A, Verwilligen R, Depuydt M, Newton G, Rattik S, et al. Increased lymphocyte activation and atherosclerosis in CD47-deficient mice. Sci Rep. 2019;9:10608 pubmed 出版商
Zhou X, Yu J, Cheng X, Zhao B, Manyam G, Zhang L, et al. The deubiquitinase Otub1 controls the activation of CD8+ T cells and NK cells by regulating IL-15-mediated priming. Nat Immunol. 2019;20:879-889 pubmed 出版商
Sharma N, Vacher J, Allison J. TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion. Proc Natl Acad Sci U S A. 2019;116:10453-10462 pubmed 出版商
Zhou L, Chu C, Teng F, Bessman N, Goc J, Santosa E, et al. Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Nature. 2019;568:405-409 pubmed 出版商
Stokes K, Cortez Retamozo V, Acosta J, Lauderback B, Robles Oteiza C, Cicchini M, et al. Natural killer cells limit the clearance of senescent lung adenocarcinoma cells. Oncogenesis. 2019;8:24 pubmed 出版商
Bek S, Stritzke F, Wintges A, Nedelko T, Böhmer D, Fischer J, et al. Targeting intrinsic RIG-I signaling turns melanoma cells into type I interferon-releasing cellular antitumor vaccines. Oncoimmunology. 2019;8:e1570779 pubmed 出版商
Wang A, Pope S, Weinstein J, Yu S, Zhang C, Booth C, et al. Specific sequences of infectious challenge lead to secondary hemophagocytic lymphohistiocytosis-like disease in mice. Proc Natl Acad Sci U S A. 2019;116:2200-2209 pubmed 出版商
Liu M, O Connor R, Trefely S, Graham K, Snyder N, Beatty G. Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal. Nat Immunol. 2019;20:265-275 pubmed 出版商
Andre P, Denis C, Soulas C, Bourbon Caillet C, Lopez J, Arnoux T, et al. Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells. Cell. 2018;175:1731-1743.e13 pubmed 出版商
Mahr B, Pilat N, Granofszky N, Wiletel M, Muckenhuber M, Maschke S, et al. Hybrid resistance to parental bone marrow grafts in nonlethally irradiated mice. Am J Transplant. 2019;19:591-596 pubmed 出版商
Harmon J, Spengler J, Coleman McCray J, Nichol S, Spiropoulou C, McElroy A. CD4 T Cells, CD8 T Cells, and Monocytes Coordinate To Prevent Rift Valley Fever Virus Encephalitis. J Virol. 2018;92: pubmed 出版商
Webster B, Werneke S, Zafirova B, This S, Coléon S, Decembre E, et al. Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses. elife. 2018;7: pubmed 出版商
Abel A, Tiwari A, Gerbec Z, Siebert J, Yang C, Schloemer N, et al. IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. Front Immunol. 2018;9:1168 pubmed 出版商
García Nores G, Ly C, Cuzzone D, Kataru R, Hespe G, Torrisi J, et al. CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema. Nat Commun. 2018;9:1970 pubmed 出版商
Manske K, Kallin N, König V, Schneider A, Kurz S, Bosch M, et al. Outcome of Antiviral Immunity in the Liver Is Shaped by the Level of Antigen Expressed in Infected Hepatocytes. Hepatology. 2018;68:2089-2105 pubmed 出版商
Hatfield S, Daniels K, O Donnell C, Waggoner S, Welsh R. Weak vaccinia virus-induced NK cell regulation of CD4 T cells is associated with reduced NK cell differentiation and cytolytic activity. Virology. 2018;519:131-144 pubmed 出版商
Burrack K, Huggins M, Taras E, Dougherty P, Henzler C, Yang R, et al. Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells. Immunity. 2018;48:760-772.e4 pubmed 出版商
Blass E, Aid M, Martinot A, Larocca R, Kang Z, Badamchi Zadeh A, et al. Adenovirus Vector Vaccination Impacts NK Cell Rheostat Function following Lymphocytic Choriomeningitis Virus Infection. J Virol. 2018;92: pubmed 出版商
Zamarin D, Ricca J, Sadekova S, Oseledchyk A, Yu Y, Blumenschein W, et al. PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy. J Clin Invest. 2018;128:1413-1428 pubmed 出版商
Hoves S, Ooi C, Wolter C, Sade H, Bissinger S, Schmittnaegel M, et al. Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity. J Exp Med. 2018;215:859-876 pubmed 出版商
Xiao Q, Wu J, Wang W, Chen S, Zheng Y, Yu X, et al. DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation. Nat Med. 2018;24:262-270 pubmed 出版商
Glasner A, Levi A, Enk J, Isaacson B, Viukov S, Orlanski S, et al. NKp46 Receptor-Mediated Interferon-? Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis. Immunity. 2018;48:107-119.e4 pubmed 出版商
Chockley P, Chen J, Chen G, Beer D, Standiford T, Keshamouni V. Epithelial-mesenchymal transition leads to NK cell-mediated metastasis-specific immunosurveillance in lung cancer. J Clin Invest. 2018;128:1384-1396 pubmed 出版商
Zhang Y, Li N, Suh H, Irvine D. Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity. Nat Commun. 2018;9:6 pubmed 出版商
Engblom C, Pfirschke C, Zilionis R, da Silva Martins J, Bos S, Courties G, et al. Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils. Science. 2017;358: pubmed 出版商
Barkal A, Weiskopf K, Kao K, Gordon S, Rosental B, Yiu Y, et al. Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy. Nat Immunol. 2018;19:76-84 pubmed 出版商
Brooks J, Fleischmann Mundt B, Woller N, Niemann J, Ribback S, Peters K, et al. Perioperative, Spatiotemporally Coordinated Activation of T and NK Cells Prevents Recurrence of Pancreatic Cancer. Cancer Res. 2018;78:475-488 pubmed 出版商
Alice A, Kramer G, Bambina S, Baird J, Bahjat K, Gough M, et al. Amplifying IFN-γ Signaling in Dendritic Cells by CD11c-Specific Loss of SOCS1 Increases Innate Immunity to Infection while Decreasing Adaptive Immunity. J Immunol. 2018;200:177-185 pubmed 出版商
Molgora M, Bonavita E, Ponzetta A, Riva F, Barbagallo M, Jaillon S, et al. IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity. Nature. 2017;551:110-114 pubmed 出版商
Skyberg J, Lacey C. Hematopoietic MyD88 and IL-18 are essential for IFN-?-dependent restriction of type A Francisella tularensis infection. J Leukoc Biol. 2017;102:1441-1450 pubmed 出版商
Bartee M, Dunlap K, Bartee E. Tumor-Localized Secretion of Soluble PD1 Enhances Oncolytic Virotherapy. Cancer Res. 2017;77:2952-2963 pubmed 出版商
Haas T, Heidegger S, Wintges A, Bscheider M, Bek S, Fischer J, et al. Card9 controls Dectin-1-induced T-cell cytotoxicity and tumor growth in mice. Eur J Immunol. 2017;47:872-879 pubmed 出版商
Li M, Bozzacco L, Hoffmann H, Breton G, Loschko J, Xiao J, et al. Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. J Exp Med. 2016;213:2931-2947 pubmed
Moynihan K, Opel C, Szeto G, Tzeng A, Zhu E, Engreitz J, et al. Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses. Nat Med. 2016;22:1402-1410 pubmed 出版商
Ghasemi R, Lazear E, Wang X, Arefanian S, Zheleznyak A, Carreno B, et al. Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy. Nat Commun. 2016;7:12878 pubmed 出版商
Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed 出版商
Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed 出版商
Maltez V, Tubbs A, Cook K, Aachoui Y, Falcone E, Holland S, et al. Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium. Immunity. 2015;43:987-97 pubmed 出版商
Mitchell D, Batich K, Gunn M, Huang M, Sanchez Perez L, Nair S, et al. Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients. Nature. 2015;519:366-9 pubmed 出版商
Wensveen F, Jelenčić V, Valentić S, Å estan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed 出版商
Yamada D, Elsaesser H, Lux A, Timmerman J, Morrison S, de la Torre J, et al. Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection. Immunity. 2015;42:379-390 pubmed 出版商
Walsh K, Teijaro J, Brock L, Fremgen D, Collins P, Rosen H, et al. Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy. J Virol. 2014;88:6281-93 pubmed 出版商
Guo Z, Wang X, Cheng D, Xia Z, Luan M, Zhang S. PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancer. PLoS ONE. 2014;9:e89350 pubmed 出版商
Uddin M, Zhang Y, Harton J, MacNamara K, Avram D. TNF-?-dependent hematopoiesis following Bcl11b deletion in T cells restricts metastatic melanoma. J Immunol. 2014;192:1946-53 pubmed 出版商
Richter K, Perriard G, Behrendt R, Schwendener R, Sexl V, Dunn R, et al. Macrophage and T cell produced IL-10 promotes viral chronicity. PLoS Pathog. 2013;9:e1003735 pubmed 出版商
Kearl T, Jing W, Gershan J, Johnson B. Programmed death receptor-1/programmed death receptor ligand-1 blockade after transient lymphodepletion to treat myeloma. J Immunol. 2013;190:5620-8 pubmed 出版商
Dai M, Wei H, Yip Y, Feng Q, He K, Popov V, et al. Long-lasting complete regression of established mouse tumors by counteracting Th2 inflammation. J Immunother. 2013;36:248-57 pubmed 出版商
Ellermeier J, Wei J, Duewell P, Hoves S, Stieg M, Adunka T, et al. Therapeutic efficacy of bifunctional siRNA combining TGF-?1 silencing with RIG-I activation in pancreatic cancer. Cancer Res. 2013;73:1709-20 pubmed 出版商
Kodack D, Chung E, Yamashita H, Incio J, Duyverman A, Song Y, et al. Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Proc Natl Acad Sci U S A. 2012;109:E3119-27 pubmed 出版商
Hervieu A, Rébé C, Vegran F, Chalmin F, Bruchard M, Vabres P, et al. Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth. J Invest Dermatol. 2013;133:499-508 pubmed 出版商
Monticelli L, Sonnenberg G, Abt M, Alenghat T, Ziegler C, Doering T, et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol. 2011;12:1045-54 pubmed 出版商
产品信息
目录号 :
BE0036-100毫克
产品名称 :
InVivoMAb抗小鼠NK1.1
宿主 :
小鼠
克隆性 :
单克隆
标记/共轭 :
No
抗原修饰 :
No
类别 :
抗体
规格 :
100毫克
Regular Price :
$4,280.00
Academic Price :
2, 782.00美元
克隆名称 :
PK136
抗体亚型 :
PK136
免疫原 :
Mouse spleen and bone marrow cells enriched for NK1+ cells
反应物种 :
小鼠
浓度/数量 :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo NK cell depletion, Flow cytometry
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
更多信息或购买 :
公司信息
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
公司总部: 美国