产品简要
公司名称 :
Bio X Cell
产品类型 :
抗体
产品名称 :
InVivoPlus anti-mouse TIM-3 (CD366)
目录 :
BP0115-5毫克
规格 :
5毫克
价格 :
1, 700.00美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
Pembrolizumab
反应物种 :
小鼠
应用 :
流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 小鼠; 图 5c
Zhang H, Song Y, Yang H, Liu Z, Gao L, Liang X, et al. Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis. Oncogene. 2018;37:2456-2468 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 2
Tripathi S, Chabtini L, Dakle P, Smith B, Akiba H, Yagita H, et al. Effect of TIM-3 Blockade on the Immunophenotype and Cytokine Profile of Murine Uterine NK Cells. PLoS ONE. 2015;10:e0123439 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 3
  • 流式细胞仪; 小鼠; 图 2a
Ju Y, Shang X, Liu Z, Zhang J, Li Y, Shen Y, et al. The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis. Mol Immunol. 2014;58:85-91 pubmed 出版商
Zhu H, Zhang L, Wu Y, Dong B, Guo W, Wang M, et al. T-ALL leukemia stem cell 'stemness' is epigenetically controlled by the master regulator SPI1. elife. 2018;7: pubmed 出版商
Sade Feldman M, Yizhak K, Bjorgaard S, Ray J, de Boer C, Jenkins R, et al. Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma. Cell. 2018;175:998-1013.e20 pubmed 出版商
Splitt S, Souza S, Valentine K, Castellanos B, Curd A, Hoyer K, et al. PD-L1, TIM-3, and CTLA-4 Blockade Fails To Promote Resistance to Secondary Infection with Virulent Strains of Toxoplasma gondii. Infect Immun. 2018;86: pubmed 出版商
Liu J, Wu L, Yang L, Deng W, Mao L, Wu H, et al. Blockade of TIM3 relieves immunosuppression through reducing regulatory T cells in head and neck cancer. J Exp Clin Cancer Res. 2018;37:44 pubmed 出版商
Teigler J, Zelinskyy G, Eller M, Bolton D, Marovich M, Gordon A, et al. Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection. J Virol. 2017;91: pubmed 出版商
Vazquez Mateo C, Collins J, Fleury M, Dooms H. Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7R? antibodies in NOD mice. BMC Immunol. 2017;18:18 pubmed 出版商
Kang C, Dutta A, Chang L, Mahalingam J, Lin Y, Chiang J, et al. Apoptosis of tumor infiltrating effector TIM-3+CD8+ T cells in colon cancer. Sci Rep. 2015;5:15659 pubmed 出版商
Kurtulus S, Sakuishi K, Ngiow S, Joller N, Tan D, Teng M, et al. TIGIT predominantly regulates the immune response via regulatory T cells. J Clin Invest. 2015;125:4053-62 pubmed 出版商
Ngiow S, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, et al. A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1. Cancer Res. 2015;75:3800-11 pubmed 出版商
Erickson J, Rogers M, Hastings A, Tollefson S, Williams J. Programmed death-1 impairs secondary effector lung CD8⁺ T cells during respiratory virus reinfection. J Immunol. 2014;193:5108-17 pubmed 出版商
Mittal D, Young A, Stannard K, Yong M, Teng M, Allard B, et al. Antimetastatic effects of blocking PD-1 and the adenosine A2A receptor. Cancer Res. 2014;74:3652-8 pubmed 出版商
Dolina J, Braciale T, Hahn Y. Liver-primed CD8+ T cells suppress antiviral adaptive immunity through galectin-9-independent T-cell immunoglobulin and mucin 3 engagement of high-mobility group box 1 in mice. Hepatology. 2014;59:1351-65 pubmed 出版商
Dietze K, Zelinskyy G, Liu J, Kretzmer F, Schimmer S, Dittmer U. Combining regulatory T cell depletion and inhibitory receptor blockade improves reactivation of exhausted virus-specific CD8+ T cells and efficiently reduces chronic retroviral loads. PLoS Pathog. 2013;9:e1003798 pubmed 出版商
McGray A, Hallett R, Bernard D, Swift S, Zhu Z, Teoderascu F, et al. Immunotherapy-induced CD8+ T cells instigate immune suppression in the tumor. Mol Ther. 2014;22:206-18 pubmed 出版商
Zelinskyy G, Myers L, Dietze K, Gibbert K, Roggendorf M, Liu J, et al. Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication. J Immunol. 2011;187:3730-7 pubmed 出版商
产品信息
目录号 :
BP0115-5毫克
产品名称 :
InVivoPlus anti-mouse TIM-3 (CD366)
宿主 :
大鼠
克隆性 :
单克隆
标记/共轭 :
No
抗原修饰 :
No
类别 :
抗体
规格 :
5毫克
Regular Price :
$2,615.00
Academic Price :
1, 700.00美元
克隆名称 :
Pembrolizumab
抗体亚型 :
RMT3-23
免疫原 :
重组小鼠TIM-3
反应物种 :
小鼠
浓度/数量 :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo TIM-3 neutralization, in vitro TIM-3 blocking, Flow cytometry
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
更多信息或购买 :
公司信息
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
公司总部: 美国