产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化抗小鼠CD3ε
目录 :
100302
规格 :
500微克
价格 :
72美元
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
未共轭
克隆名称 :
145-2C11
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 中和反应, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片, 抑制或激活实验, mass cytometry
更多信息或购买 :
文章摘录数: 354
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:700; 图 2d
Rizvi Z, Dalal R, Sadhu S, Kumar Y, Kumar S, Gupta S, et al. High-salt diet mediates interplay between NK cells and gut microbiota to induce potent tumor immunity. Sci Adv. 2021;7:eabg5016 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:300; 图 2f
Moreira T, Mangani D, Cox L, Leibowitz J, Lobo E, Oliveira M, et al. PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis. Nat Commun. 2021;12:4907 pubmed 出版商
  • 流式细胞仪; 小鼠
Gvozdeva O, Achasova K, Litvinova N, Kozhevnikova E, Litvinova E. Female Scent Activated Expression of Arginase1 and Inducible NO-Synthetase in Lung of BALB/c Male Mice. Animals (Basel). 2021;11: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6a
Innamarato P, Morse J, Mackay A, Asby S, Beatty M, Blauvelt J, et al. Intralesional injection of rose bengal augments the efficacy of gemcitabine chemotherapy against pancreatic tumors. BMC Cancer. 2021;21:756 pubmed 出版商
  • 抑制或激活实验; 小鼠; 2 ug/ml; 图 5b
Uyanik B, Goloudina A, Akbarali A, Grigorash B, Petukhov A, Singhal S, et al. Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses. Nat Commun. 2021;12:3622 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400; 图 2m
Roca C, Burton O, Gergelits V, Prezzemolo T, Whyte C, Halpert R, et al. AutoSpill is a principled framework that simplifies the analysis of multichromatic flow cytometry data. Nat Commun. 2021;12:2890 pubmed 出版商
  • mass cytometry; 小鼠
Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton K, Tian L, et al. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021;125:176-189 pubmed 出版商
  • 流式细胞仪; 小鼠
Chu A, Kok S, TSUI J, Lin M, Aguirre B, Wadehra M. Epithelial membrane protein 2 (Emp2) modulates innate immune cell population recruitment at the maternal-fetal interface. J Reprod Immunol. 2021;145:103309 pubmed 出版商
  • 流式细胞仪; 小鼠
Yoon S, Song S, Shin J, Kang S, Kim H, You H. Protective Effects of Korean Herbal Remedy against Airway Inflammation in an Allergic Asthma by Suppressing Eosinophil Recruitment and Infiltration in Lung. Antioxidants (Basel). 2020;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4d
Ray S, Chee L, Matson D, Palermo N, Bresnick E, Hewitt K. Sterile α-motif domain requirement for cellular signaling and survival. J Biol Chem. 2020;295:7113-7125 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4
Eastman A, Xu J, Bermik J, Potchen N, den Dekker A, Neal L, et al. Epigenetic stabilization of DC and DC precursor classical activation by TNFα contributes to protective T cell polarization. Sci Adv. 2019;5:eaaw9051 pubmed 出版商
  • 抑制或激活实验; 小鼠; 1-10 ug/ml; 图 2a
Krovi S, Kappler J, Marrack P, Gapin L. Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules. Proc Natl Acad Sci U S A. 2019;116:22252-22261 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6a
Jia S, Li W, Liu P, Xu L. A role of eosinophils in mediating the anti-tumour effect of cryo-thermal treatment. Sci Rep. 2019;9:13214 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Takagaki S, Yamashita R, Hashimoto N, Sugihara K, Kanari K, Tabata K, et al. Galactosyl carbohydrate residues on hematopoietic stem/progenitor cells are essential for homing and engraftment to the bone marrow. Sci Rep. 2019;9:7133 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 5c
Klein J, Moses K, Zelinskyy G, Sody S, Buer J, Lang S, et al. Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth. Nat Commun. 2017;8:14600 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6e
Obeid S, Wankell M, Charrez B, Sternberg J, Kreuter R, Esmaili S, et al. Adiponectin confers protection from acute colitis and restricts a B cell immune response. J Biol Chem. 2017;292:6569-6582 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Ramos G, van den Berg A, Nunes Silva V, Weirather J, Peters L, Burkard M, et al. Myocardial aging as a T-cell-mediated phenomenon. Proc Natl Acad Sci U S A. 2017;114:E2420-E2429 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Yanagita T, Murata Y, Tanaka D, Motegi S, Arai E, Daniwijaya E, et al. Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy. JCI Insight. 2017;2:e89140 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3e
Rombouts M, Cools N, Grootaert M, de Bakker F, Van Brussel I, Wouters A, et al. Long-Term Depletion of Conventional Dendritic Cells Cannot Be Maintained in an Atherosclerotic Zbtb46-DTR Mouse Model. PLoS ONE. 2017;12:e0169608 pubmed 出版商
  • 流式细胞仪; 小鼠
Rychtarčíková Z, Lettlova S, Tomkova V, Korenkova V, Langerova L, Simonova E, et al. Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism. Oncotarget. 2017;8:6376-6398 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4
Bieber K, Witte M, Sun S, Hundt J, Kalies K, Dräger S, et al. T cells mediate autoantibody-induced cutaneous inflammation and blistering in epidermolysis bullosa acquisita. Sci Rep. 2016;6:38357 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
  • 酶联免疫吸附测定; 小鼠
Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
  • 流式细胞仪; 小鼠
Shifrin N, Kissiov D, Ardolino M, Joncker N, Raulet D. Differential Role of Hematopoietic and Nonhematopoietic Cell Types in the Regulation of NK Cell Tolerance and Responsiveness. J Immunol. 2016;197:4127-4136 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:50; 图 s2b
Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, et al. Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. Nat Commun. 2016;7:13130 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 5a
Ishikura S, Tsunoda T, Nakabayashi K, Doi K, Koyanagi M, Hayashi K, et al. Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells. Biochim Biophys Acta. 2016;1859:1398-1410 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Kritikou J, Dahlberg C, Baptista M, Wagner A, Banerjee P, Gwalani L, et al. IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo. Sci Rep. 2016;6:30636 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:300; 图 4d
Riedel A, Shorthouse D, Haas L, Hall B, Shields J. Tumor-induced stromal reprogramming drives lymph node transformation. Nat Immunol. 2016;17:1118-27 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 2a
Contreras F, Prado C, Gonzalez H, Franz D, Osorio Barrios F, Osorio F, et al. Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity. J Immunol. 2016;196:4143-9 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Hua J, Stevenson W, Dohlman T, Inomata T, Tahvildari M, Calcagno N, et al. Graft Site Microenvironment Determines Dendritic Cell Trafficking Through the CCR7-CCL19/21 Axis. Invest Ophthalmol Vis Sci. 2016;57:1457-67 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 3
  • 流式细胞仪; 小鼠; 图 4
Apostolidis S, Rodríguez Rodríguez N, Suárez Fueyo A, Dioufa N, Ozcan E, Crispín J, et al. Phosphatase PP2A is requisite for the function of regulatory T cells. Nat Immunol. 2016;17:556-64 pubmed 出版商
  • 流式细胞仪; 小鼠
Flach A, Litke T, Strauss J, Haberl M, Gómez C, Reindl M, et al. Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease. Proc Natl Acad Sci U S A. 2016;113:3323-8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
  • 免疫细胞化学; 小鼠; 1:200; 图 2
Foy S, Sennino B, dela Cruz T, Cote J, Gordon E, Kemp F, et al. Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice. PLoS ONE. 2016;11:e0150084 pubmed 出版商
  • 抑制或激活实验; 小鼠
Hwang S, Jang S, Kim M, Kim L, Kim B, Kim H, et al. YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity. Nat Commun. 2016;7:10789 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Pelly V, Kannan Y, Coomes S, Entwistle L, Rückerl D, Seddon B, et al. IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection. Mucosal Immunol. 2016;9:1407-1417 pubmed 出版商
  • 抑制或激活实验; 小鼠; 10 ug/ml; 图 4
Kim K, Kim N, Lee G. Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region. PLoS ONE. 2016;11:e0148576 pubmed 出版商
  • 流式细胞仪; 小鼠; 30 ug/ml; 图 s1
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Yasuma K, Yasunaga J, Takemoto K, Sugata K, Mitobe Y, Takenouchi N, et al. HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT). PLoS Pathog. 2016;12:e1005372 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, et al. Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma. Nat Med. 2015;21:1272-9 pubmed 出版商
  • 免疫组化-冰冻切片; 人类
  • 流式细胞仪; 人类; 图 1
Sewald X, Ladinsky M, Uchil P, Beloor J, Pi R, Herrmann C, et al. Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection. Science. 2015;350:563-567 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Murayama M, Kakuta S, Inoue A, Umeda N, Yonezawa T, Maruhashi T, et al. CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis. Nat Commun. 2015;6:8483 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s7
McCormack R, de Armas L, Shiratsuchi M, Fiorentino D, Olsson M, Lichtenheld M, et al. Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria. elife. 2015;4: pubmed 出版商
  • 流式细胞仪; 小鼠
Aparicio Domingo P, Romera Hernandez M, Karrich J, Cornelissen F, Papazian N, Lindenbergh Kortleve D, et al. Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage. J Exp Med. 2015;212:1783-91 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Kamimura D, Katsunuma K, Arima Y, Atsumi T, Jiang J, Bando H, et al. KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR. Nat Commun. 2015;6:7474 pubmed 出版商
  • 抑制或激活实验; 人类; 图 1
McCully M, Collins P, Hughes T, Thomas C, Billen J, O Donnell V, et al. Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells. J Immunol. 2015;195:96-104 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Iwai H, Funatogawa K, Matsumura K, Kato Miyazawa M, Kirikae F, Kiga K, et al. MicroRNA-155 knockout mice are susceptible to Mycobacterium tuberculosis infection. Tuberculosis (Edinb). 2015;95:246-50 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Brunner P, Glitzner E, Reininger B, Klein I, Stary G, Mildner M, et al. CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin. Exp Dermatol. 2015;24:522-8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Liu B, Lee J, Chen C, Hershey G, Wang Y. Collaborative interactions between type 2 innate lymphoid cells and antigen-specific CD4+ Th2 cells exacerbate murine allergic airway diseases with prominent eosinophilia. J Immunol. 2015;194:3583-93 pubmed 出版商
  • 免疫沉淀; 小鼠
Richardson E, Shukla S, Sweet D, Wearsch P, Tsichlis P, Boom W, et al. Toll-like receptor 2-dependent extracellular signal-regulated kinase signaling in Mycobacterium tuberculosis-infected macrophages drives anti-inflammatory responses and inhibits Th1 polarization of responding T cells. Infect Immun. 2015;83:2242-54 pubmed 出版商
  • 抑制或激活实验; 小鼠; 5 ug/ml
  • 流式细胞仪; 小鼠
Rao E, Zhang Y, Zhu G, Hao J, Persson X, Egilmez N, et al. Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death. Oncotarget. 2015;6:7944-58 pubmed
  • 流式细胞仪; 小鼠; 图 2
Stack G, Jones E, Marsden M, Stacey M, Snelgrove R, Lacaze P, et al. CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue. PLoS Pathog. 2015;11:e1004641 pubmed 出版商
  • 抑制或激活实验; 小鼠; 20 ug/ml; 图 1
Fos C, Bécart S, Canonigo Balancio A, Boehning D, Altman A. Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells. Sci Signal. 2014;7:ra93 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 3
Ishikura S, Ogawa M, Doi K, Matsuzaki H, Iwaihara Y, Tanaka Y, et al. Zfat-deficient CD4⁺ CD8⁺ double-positive thymocytes are susceptible to apoptosis with deregulated activation of p38 and JNK. J Cell Biochem. 2015;116:149-57 pubmed 出版商
  • 流式细胞仪; 小鼠
Chen J, Zhao Y, Zhang C, Chen H, Feng J, Chi X, et al. Persistent hepatitis C virus infections and hepatopathological manifestations in immune-competent humanized mice. Cell Res. 2014;24:1050-66 pubmed 出版商
  • 流式细胞仪; 小鼠
Budde H, Kolb S, Salinas Tejedor L, Wulf G, Reichardt H, Riggert J, et al. Modified extracorporeal photopheresis with cells from a healthy donor for acute graft-versus-host disease in a mouse model. PLoS ONE. 2014;9:e105896 pubmed 出版商
  • 流式细胞仪; 小鼠
Xu Y, Hyun Y, Lim K, Lee H, Cummings R, Gerber S, et al. Optogenetic control of chemokine receptor signal and T-cell migration. Proc Natl Acad Sci U S A. 2014;111:6371-6 pubmed 出版商
  • 抑制或激活实验; 小鼠; 0.25 ug/ml
Koga T, Hedrich C, Mizui M, Yoshida N, Otomo K, Lieberman L, et al. CaMK4-dependent activation of AKT/mTOR and CREM-? underlies autoimmunity-associated Th17 imbalance. J Clin Invest. 2014;124:2234-45 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Yan J, Villarreal D, Racine T, Chu J, Walters J, Morrow M, et al. Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine. Vaccine. 2014;32:2833-42 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4b
Xia S, Wei J, Wang J, Sun H, Zheng W, Li Y, et al. A requirement of dendritic cell-derived interleukin-27 for the tumor infiltration of regulatory T cells. J Leukoc Biol. 2014;95:733-742 pubmed
  • 流式细胞仪; 小鼠
Wickström S, Oberg L, Kärre K, Johansson M. A genetic defect in mice that impairs missing self recognition despite evidence for normal maturation and MHC class I-dependent education of NK cells. J Immunol. 2014;192:1577-86 pubmed 出版商
Morales Mantilla D, Kain B, Le D, Flores A, Paust S, King K. Hematopoietic stem and progenitor cells improve survival from sepsis by boosting immunomodulatory cells. elife. 2022;11: pubmed 出版商
Sun L, Zhang W, Zhao L, Zhao Y, Wang F, Lew A, et al. Self-Tolerance of Vascular Tissues Is Broken Down by Vascular Dendritic Cells in Response to Systemic Inflammation to Initiate Regional Autoinflammation. Front Immunol. 2022;13:823853 pubmed 出版商
Chen Y, Liu R, Cui Y, Hettinghouse A, Fu W, Zhang L, et al. Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases. Arthritis Res Ther. 2022;24:27 pubmed 出版商
Nagatake T, Kishino S, Urano E, Murakami H, Kitamura N, Konishi K, et al. Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques. Mucosal Immunol. 2022;15:289-300 pubmed 出版商
Shiozawa S, Tsumiyama K, Miyazaki Y, Uto K, Sakurai K, Nakashima T, et al. DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus. iScience. 2022;25:103537 pubmed 出版商
Wu G, Murugesan G, Nagala M, McCraw A, Haslam S, Dell A, et al. Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses. Wellcome Open Res. 2021;6:134 pubmed 出版商
Tanaka Y, Nakao A, Miyake Y, Higashi Y, Tanigaki R, Kataoka T. Small Molecule Inhibitors Targeting Nuclear Factor κB Activation Markedly Reduce Expression of Interleukin-2, but Not Interferon-γ, Induced by Phorbol Esters and Calcium Ionophores. Int J Mol Sci. 2021;22: pubmed 出版商
Ejima R, Akiyama M, Sato H, Tomioka S, Yakabe K, Kimizuka T, et al. Seaweed Dietary Fiber Sodium Alginate Suppresses the Migration of Colonic Inflammatory Monocytes and Diet-Induced Metabolic Syndrome via the Gut Microbiota. Nutrients. 2021;13: pubmed 出版商
Kobayashi A, Ito A, Shirakawa I, Tamura A, Tomono S, Shindou H, et al. Dietary Supplementation With Eicosapentaenoic Acid Inhibits Plasma Cell Differentiation and Attenuates Lupus Autoimmunity. Front Immunol. 2021;12:650856 pubmed 出版商
Lu S, De Neef E, Thomas J, SABIO E, Rousseau B, Gigoux M, et al. Pharmacologic modulation of RNA splicing enhances anti-tumor immunity. Cell. 2021;184:4032-4047.e31 pubmed 出版商
Debackere K, Marcelis L, Demeyer S, Vanden Bempt M, Mentens N, Gielen O, et al. Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified. Nat Commun. 2021;12:3705 pubmed 出版商
Wan Mohd Zawawi W, Hibma M, Salim M, Jemon K. Hyperthermia by near infrared radiation induced immune cells activation and infiltration in breast tumor. Sci Rep. 2021;11:10278 pubmed 出版商
McLane L, Ngiow S, Chen Z, Attanasio J, Manne S, Ruthel G, et al. Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells. Cell Rep. 2021;35:109120 pubmed 出版商
Sasai M, Ma J, Okamoto M, Nishino K, Nagaoka H, Takashima E, et al. Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells. J Exp Med. 2021;218: pubmed 出版商
Wang Z, Goto Y, Allevato M, Wu V, Saddawi Konefka R, Gilardi M, et al. Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer. Nat Commun. 2021;12:2383 pubmed 出版商
Willimsky G, Beier C, Immisch L, Papafotiou G, Scheuplein V, Goede A, et al. In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo. elife. 2021;10: pubmed 出版商
Caronni N, Piperno G, Simoncello F, Romano O, Vodret S, Yanagihashi Y, et al. TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses. Nat Commun. 2021;12:2237 pubmed 出版商
Uzhachenko R, Bharti V, Ouyang Z, Blevins A, Mont S, Saleh N, et al. Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors. Cell Rep. 2021;35:108944 pubmed 出版商
Chen Z, Arai E, Khan O, Zhang Z, Ngiow S, He Y, et al. In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer. Cell. 2021;184:1262-1280.e22 pubmed 出版商
Yi M, Zhang J, Li A, Niu M, Yan Y, Jiao Y, et al. The construction, expression, and enhanced anti-tumor activity of YM101: a bispecific antibody simultaneously targeting TGF-β and PD-L1. J Hematol Oncol. 2021;14:27 pubmed 出版商
Jennings E, Lecky D, Ono M, Bending D. Application of dual Nr4a1-GFP Nr4a3-Tocky reporter mice to study T cell receptor signaling by flow cytometry. STAR Protoc. 2021;2:100284 pubmed 出版商
Becker W, Alrafas H, Busbee P, Walla M, Wilson K, Miranda K, et al. Cannabinoid Receptor Activation on Haematopoietic Cells and Enterocytes Protects against Colitis. J Crohns Colitis. 2021;15:1032-1048 pubmed 出版商
Mullins G, Valentine K, Al Kuhlani M, Davini D, Jensen K, Hoyer K. T cell signaling and Treg dysfunction correlate to disease kinetics in IL-2Rα-KO autoimmune mice. Sci Rep. 2020;10:21994 pubmed 出版商
Meryk A, Grasse M, Balasco L, Kapferer W, Grubeck Loebenstein B, Pangrazzi L. Antioxidants N-Acetylcysteine and Vitamin C Improve T Cell Commitment to Memory and Long-Term Maintenance of Immunological Memory in Old Mice. Antioxidants (Basel). 2020;9: pubmed 出版商
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产品信息
抗原 :
CD3epsilon
Apps. Abbrev. :
流式细胞仪, 免疫组化-F, 免疫沉淀, 活性的, 中和, 西方墨点法, 免疫细胞化学
目录 :
100302
克隆 :
145-2C11
产品 :
纯化抗小鼠CD3ε
抗体亚型 :
亚美尼亚仓鼠IgG
其他名称 :
CD3ε, T3, CD3
规格 :
500微克
价格(美元) :
72美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
亚美尼亚仓鼠
共轭标签/标签/标记 :
PURE
免疫原 :
H-2K b -specific mouse cytotoxic T lymphocyte clone BM10-37
应用注释 :
Clone 145-2C11 is useful for in vitro blocking of target-specific CTL-mediated cell lysis 1 , as well as T cell activation assays, inducing proliferation and cytokine production 1,2,7,12,16 . It also induces apoptosis in immature thymocytes 32 , and in vivo T cell depletion 8-10 . Additional reported applications (for relevant formats of this clone) include: immunoprecipitation 1 , immunohistochemical staining 14,15 of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections, Western blotting 4 , complement-mediated cytotoxicity 6 , in vitro and in vivo stimulation of T cells 1,2,7,12,16 , immunofluorescent staining 5 , and in vivo T cell depletion8-10. The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells 11 . Clone 145-2C11 is not recommended for formalin-fixed paraffin embedded sections. The LEAF™ purified antibody (Endotoxin 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 100314). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 100340) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin 0.01 EU/µg).
更多信息或购买 :
公司信息
BioLegend
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https://www.biolegend.com
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公司总部: 美国
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