产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Pacific Blue™ anti-mouse CD4
目录 :
100427
规格 :
25微克
价格 :
94美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
Pacific Blue荧光染料
克隆名称 :
GK1.5
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 57
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:100; 图 2s3e
Glassman C, Su L, Majri Morrison S, Winkelmann H, Mo F, Li P, et al. Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist. elife. 2021;10: pubmed 出版商
  • 流式细胞仪; 小鼠
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  • 流式细胞仪; 小鼠; 1:500; 图 1j
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  • 流式细胞仪; 小鼠; 5 ug/ml; 图 2j, 3a, s3a, s12r
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  • 流式细胞仪; 小鼠; 图 s16c
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  • 流式细胞仪; 小鼠; 图 1a
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  • 流式细胞仪; 小鼠; 图 S2
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  • 流式细胞仪; 小鼠; 图 s3
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Tian D, Yang L, Wang S, Zhu Y, Shi W, Zhang C, et al. Double negative T cells mediate Lag3-dependent antigen-specific protection in allergic asthma. Nat Commun. 2019;10:4246 pubmed 出版商
Zheng X, Oduro J, Boehme J, Borkner L, Ebensen T, Heise U, et al. Mucosal CD8+ T cell responses induced by an MCMV based vaccine vector confer protection against influenza challenge. PLoS Pathog. 2019;15:e1008036 pubmed 出版商
Kobayashi S, Sakurai T, So T, Shiota Y, Asao A, Phung H, et al. TNF Receptor-Associated Factor 5 Limits Function of Plasmacytoid Dendritic Cells by Controlling IFN Regulatory Factor 5 Expression. J Immunol. 2019;203:1447-1456 pubmed 出版商
Vono M, Eberhardt C, Auderset F, Mastelic Gavillet B, Lemeille S, Christensen D, et al. Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers. Cell Rep. 2019;28:1773-1784.e5 pubmed 出版商
Dangaj D, Bruand M, Grimm A, Ronet C, Barras D, Duttagupta P, et al. Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors. Cancer Cell. 2019;35:885-900.e10 pubmed 出版商
Zhou J, Huang S, Wang Z, Huang J, Xu L, Tang X, et al. Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation. Nat Commun. 2019;10:2427 pubmed 出版商
Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, et al. Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity. 2019;: pubmed 出版商
Zhao J, Wen X, Tian L, Li T, Xu C, Wen X, et al. Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer. Nat Commun. 2019;10:899 pubmed 出版商
Wu B, Zhang S, Guo Z, Wang G, Zhang G, Xie L, et al. RAS P21 Protein Activator 3 (RASA3) Specifically Promotes Pathogenic T Helper 17 Cell Generation by Repressing T-Helper-2-Cell-Biased Programs. Immunity. 2018;49:886-898.e5 pubmed 出版商
Wang Z, Yin W, Zhu L, Li J, Yao Y, Chen F, et al. Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production. Immunity. 2018;49:80-92.e7 pubmed 出版商
Lu Y, Wang Q, Xue G, Bi E, Ma X, Wang A, et al. Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. Cancer Cell. 2018;33:1048-1060.e7 pubmed 出版商
Liu S, Xia Q, Wu X, Sun F, Hu Q, Wu J, et al. Stimulator of Interferon Genes in Classical Dendritic Cells Controls Mucosal Th17 Responses to Cyclic Dinucleotides for Host Defenses Against Microbial Infections in Gut. Front Immunol. 2018;9:1085 pubmed 出版商
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产品信息
抗原 :
CD4
Apps. Abbrev. :
流式细胞仪
目录 :
100427
克隆 :
GK1.5
产品 :
Pacific Blue™ anti-mouse CD4
抗体亚型 :
Rat IgG2b, κ
其他名称 :
L3T4, T4
规格 :
25微克
价格(美元) :
94美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PB
免疫原 :
小鼠CTL克隆V4
应用注释 :
Additional reported applications (for the relevant formats) include: blocking of CD4 + T cell activation 1,4,11 , thymocyte costimulation 3 , in vitro and in vivo depletion 2,5-8 , blocking of egg-sperm cell adhesion 1,4 , immunohistochemical staining of acetone-fixed frozen sections 9,10 , immunoprecipitation 1,2 , and spatial biology (IBEX) 12,13 . The GK1.5 antibody is able to block CD4 mediated cell adhesion and T cell activation. Binding of GK1.5 antibody to CD4 T cells can be blocked by RM4-5 antibody, but not RM4-4 antibody. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 100442) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。