产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
PerCP抗小鼠CD4
目录 :
100431
规格 :
25微克
价格 :
106美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PerCP
克隆名称 :
GK1.5
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 36
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 1d
Kono M, Komatsuda H, Yamaki H, Kumai T, Hayashi R, Wakisaka R, et al. Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma. Oncoimmunology. 2022;11:2021619 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Prado C, Gaiazzi M, Gonzalez H, Ugalde V, Figueroa A, Osorio Barrios F, et al. Dopaminergic Stimulation of Myeloid Antigen-Presenting Cells Attenuates Signal Transducer and Activator of Transcription 3-Activation Favouring the Development of Experimental Autoimmune Encephalomyelitis. Front Immunol. 2018;9:571 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Ernszt D, Banfai K, Kellermayer Z, Pap A, Lord J, Pongracz J, et al. PPARgamma Deficiency Counteracts Thymic Senescence. Front Immunol. 2017;8:1515 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
  • 流式细胞仪; 小鼠; 图 2a
Contreras F, Prado C, Gonzalez H, Franz D, Osorio Barrios F, Osorio F, et al. Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity. J Immunol. 2016;196:4143-9 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Salinas N, Olguín J, Castellanos C, Saavedra R. T cell suppression in vitro during Toxoplasma gondii infection is the result of IL-2 competition between Tregs and T cells leading to death of proliferating T cells. Scand J Immunol. 2014;79:1-11 pubmed 出版商
Zhao J, Ye H, Lu Q, Wang K, Chen X, Song J, et al. Inhibition of post-surgery tumour recurrence via a sprayable chemo-immunotherapy gel releasing PD-L1 antibody and platelet-derived small EVs. J Nanobiotechnology. 2022;20:62 pubmed 出版商
Jiang Q, Qiao B, Lin X, Cao J, Zhang N, Guo H, et al. A hydrogen peroxide economizer for on-demand oxygen production-assisted robust sonodynamic immunotherapy. Theranostics. 2022;12:59-75 pubmed 出版商
Marks K, Flaherty S, Patterson K, STRATTON M, Martinez G, Reynolds J. Toll-like receptor 2 induces pathogenicity in Th17 cells and reveals a role for IPCEF in regulating Th17 cell migration. Cell Rep. 2021;35:109303 pubmed 出版商
Tacconi C, Commerford C, Dieterich L, Schwager S, He Y, Ikenberg K, et al. CD169+ lymph node macrophages have protective functions in mouse breast cancer metastasis. Cell Rep. 2021;35:108993 pubmed 出版商
Evans R, Antonelou M, Sathiananthamoorthy S, Rega M, Henderson S, Ceron Gutierrez L, et al. Inherited salt-losing tubulopathies are associated with immunodeficiency due to impaired IL-17 responses. Nat Commun. 2020;11:4368 pubmed 出版商
Yi X, Zhou H, Chao Y, Xiong S, Zhong J, Chai Z, et al. Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer. Sci Adv. 2020;6:eaba3546 pubmed 出版商
Guo X, Pan Y, Xiong M, Sanapala S, Anastasaki C, Cobb O, et al. Midkine activation of CD8+ T cells establishes a neuron-immune-cancer axis responsible for low-grade glioma growth. Nat Commun. 2020;11:2177 pubmed 出版商
Chao Y, Liang C, Tao H, Du Y, Wu D, Dong Z, et al. Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses. Sci Adv. 2020;6:eaaz4204 pubmed 出版商
Aguilera T, Elghonaimy E, Shehade H, Rafat M, Castellini L, Jiang D, et al. Induced Tumor Heterogeneity Reveals Factors Informing Radiation and Immunotherapy Combinations. Clin Cancer Res. 2020;26:2972-2985 pubmed 出版商
Chen C, Chencheng Z, Cuiying L, Xiaokun G. Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells. Front Cell Neurosci. 2020;14:8 pubmed 出版商
Wolf Y, Bartok O, Patkar S, Eli G, Cohen S, Litchfield K, et al. UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma. Cell. 2019;179:219-235.e21 pubmed 出版商
Tran T, Guha R, Portugal S, Skinner J, Ongoiba A, Bhardwaj J, et al. A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation. Immunity. 2019;51:750-765.e10 pubmed 出版商
Komban R, Strömberg A, Biram A, Cervin J, Lebrero Fernández C, Mabbott N, et al. Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome. Nat Commun. 2019;10:2423 pubmed 出版商
Nagai Y, Ji M, Zhu F, Xiao Y, Tanaka Y, Kambayashi T, et al. PRMT5 Associates With the FOXP3 Homomer and When Disabled Enhances Targeted p185erbB2/neu Tumor Immunotherapy. Front Immunol. 2019;10:174 pubmed 出版商
Zhao J, Wen X, Tian L, Li T, Xu C, Wen X, et al. Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer. Nat Commun. 2019;10:899 pubmed 出版商
Ouyang S, Zeng Q, Tang N, Guo H, Tang R, Yin W, et al. Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells. J Immunol. 2019;202:1441-1452 pubmed 出版商
Britton G, Contijoch E, Mogno I, Vennaro O, Llewellyn S, Ng R, et al. Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice. Immunity. 2019;50:212-224.e4 pubmed 出版商
Zhu W, Xu R, Du J, Fu Y, Li S, Zhang P, et al. Zoledronic acid promotes TLR-4-mediated M1 macrophage polarization in bisphosphonate-related osteonecrosis of the jaw. FASEB J. 2019;33:5208-5219 pubmed 出版商
O Malley G, Treacy O, Lynch K, Naicker S, Leonard N, Lohan P, et al. Stromal Cell PD-L1 Inhibits CD8+ T-cell Antitumor Immune Responses and Promotes Colon Cancer. Cancer Immunol Res. 2018;6:1426-1441 pubmed 出版商
Zhang J, Hou S, Gu J, Tian T, Yuan Q, Jia J, et al. S100A4 promotes colon inflammation and colitis-associated colon tumorigenesis. Oncoimmunology. 2018;7:e1461301 pubmed 出版商
Nagatake T, Suzuki H, Hirata S, Matsumoto N, Wada Y, Morimoto S, et al. Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice. Int Immunol. 2018;30:471-481 pubmed 出版商
Lino A, Dang V, Lampropoulou V, Welle A, Joedicke J, Pohar J, et al. LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells. Immunity. 2018;49:120-133.e9 pubmed 出版商
Nagatake T, Shiogama Y, Inoue A, Kikuta J, Honda T, Tiwari P, et al. The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques. J Allergy Clin Immunol. 2018;142:470-484.e12 pubmed 出版商
Probst P, Kopp J, Oxenius A, Colombo M, Ritz D, Fugmann T, et al. Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8+ T-cell Recognition of a Retroviral Antigen. Cancer Res. 2017;77:3644-3654 pubmed 出版商
Maston L, Jones D, Giermakowska W, Howard T, Cannon J, Wang W, et al. Central role of T helper 17 cells in chronic hypoxia-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2017;312:L609-L624 pubmed 出版商
Chen Q, Xu L, Liang C, Wang C, Peng R, Liu Z. Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy. Nat Commun. 2016;7:13193 pubmed 出版商
Yu H, Sui Y, Wang Y, Sato N, Frey B, Xia Z, et al. Interleukin-15 Constrains Mucosal T Helper 17 Cell Generation: Influence of Mononuclear Phagocytes. PLoS ONE. 2015;10:e0143001 pubmed 出版商
Charlton J, Tsoukatou D, Mamalaki C, Chatzidakis I. Programmed death 1 regulates memory phenotype CD4 T cell accumulation, inhibits expansion of the effector memory phenotype subset and modulates production of effector cytokines. PLoS ONE. 2015;10:e0119200 pubmed 出版商
Geng J, Zhang K, Chen L, Miao J, Yao M, Ren Y, et al. Enhancement of CD147 on M1 macrophages induces differentiation of Th17 cells in the lung interstitial fibrosis. Biochim Biophys Acta. 2014;1842:1770-82 pubmed 出版商
Blonska M, Joo D, Nurieva R, Zhao X, Chiao P, Sun S, et al. Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKK? signaling cascade. Sci Signal. 2013;6:ra110 pubmed 出版商
产品信息
抗原 :
CD4
Apps. Abbrev. :
流式细胞仪
目录 :
100431
克隆 :
GK1.5
产品 :
PerCP抗小鼠CD4
抗体亚型 :
Rat IgG2b, κ
其他名称 :
L3T4, T4
规格 :
25微克
价格(美元) :
106美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PERCP
免疫原 :
小鼠CTL克隆V4
应用注释 :
Additional reported applications (for the relevant formats) include: blocking of CD4 + T cell activation 1,4,11 , thymocyte costimulation 3 , in vitro and in vivo depletion 2,5-8 , blocking of egg-sperm cell adhesion 1,4 , immunohistochemical staining of acetone-fixed frozen sections 9,10 , immunoprecipitation 1,2 , and spatial biology (IBEX) 12,13 . The GK1.5 antibody is able to block CD4 mediated cell adhesion and T cell activation. Binding of GK1.5 antibody to CD4 T cells can be blocked by RM4-5 antibody, but not RM4-4 antibody. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 100442) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。