出版应用/物种/样本/稀释 | 参考文献 |
---|
| James O, Vandereyken M, Marchingo J, Singh F, Bray S, Wilson J, et al. IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes. Nat Commun. 2021;12:4290 pubmed 出版商
|
| Xia X, Li R, Zhou P, Xing Z, Lu C, Long Z, et al. Decreased NSG3 enhances PD-L1 expression by Erk1/2 pathway to promote pancreatic cancer progress. Am J Cancer Res. 2021;11:916-929 pubmed
|
- 流式细胞仪; 小鼠; 1:250; 图 4g
- 免疫组化; 小鼠; 图 2a
| Bhaskar A, Kumar S, Khan M, Singh A, Dwivedi V, Nandicoori V. Host sirtuin 2 as an immunotherapeutic target against tuberculosis. elife. 2020;9: pubmed 出版商
|
| Terashima Y, Toda E, Itakura M, Otsuji M, Yoshinaga S, Okumura K, et al. Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties. Nat Commun. 2020;11:609 pubmed 出版商
|
| Schafflick D, Xu C, Hartlehnert M, Cole M, Schulte Mecklenbeck A, Lautwein T, et al. Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis. Nat Commun. 2020;11:247 pubmed 出版商
|
| Schanoski A, Le T, Kaiserman D, Rowe C, Prow N, Barboza D, et al. Granzyme A in Chikungunya and Other Arboviral Infections. Front Immunol. 2019;10:3083 pubmed 出版商
|
| Lee J, Stone M, Porrett P, Thomas S, Komar C, Li J, et al. Hepatocytes direct the formation of a pro-metastatic niche in the liver. Nature. 2019;567:249-252 pubmed 出版商
|
| Wheeler M, Jaronen M, Covacu R, Zandee S, Scalisi G, Rothhammer V, et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell. 2019;176:581-596.e18 pubmed 出版商
|
| Garić D, Tao S, Ahmed E, Youssef M, Kanagaratham C, Shah J, et al. Depletion of BAFF cytokine exacerbates infection in Pseudomonas aeruginosa infected mice. J Cyst Fibros. 2019;18:349-356 pubmed 出版商
|
| Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira N, et al. Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance. Nature. 2018;553:91-95 pubmed 出版商
|
| Tripathi D, Venkatasubramanian S, Cheekatla S, Paidipally P, Welch E, Tvinnereim A, et al. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice. Nat Commun. 2016;7:13896 pubmed 出版商
|
| Moodley D, Yoshida H, Mostafavi S, Asinovski N, Ortiz Lopez A, Symanowicz P, et al. Network pharmacology of JAK inhibitors. Proc Natl Acad Sci U S A. 2016;113:9852-7 pubmed 出版商
|
| Qi X, Gurung P, Malireddi R, Karmaus P, Sharma D, Vogel P, et al. Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis. Mucosal Immunol. 2017;10:128-138 pubmed 出版商
|
| Ackerknecht M, Hauser M, Legler D, Stein J. In vivo TCR Signaling in CD4(+) T Cells Imprints a Cell-Intrinsic, Transient Low-Motility Pattern Independent of Chemokine Receptor Expression Levels, or Microtubular Network, Integrin, and Protein Kinase C Activity. Front Immunol. 2015;6:297 pubmed 出版商
|
| Suzuki H, Watari A, Hashimoto E, Yonemitsu M, Kiyono H, Yagi K, et al. C-Terminal Clostridium perfringens Enterotoxin-Mediated Antigen Delivery for Nasal Pneumococcal Vaccine. PLoS ONE. 2015;10:e0126352 pubmed 出版商
|
| OlguÃn J, Fernández J, Salinas N, Juárez I, Rodriguez Sosa M, Campuzano J, et al. Adoptive transfer of CD4(+)Foxp3(+) regulatory T cells to C57BL/6J mice during acute infection with Toxoplasma gondii down modulates the exacerbated Th1 immune response. Microbes Infect. 2015;17:586-95 pubmed 出版商
|
| Chaimowitz N, Falanga Y, Ryan J, Conrad D. Fyn kinase is required for optimal humoral responses. PLoS ONE. 2013;8:e60640 pubmed 出版商
|
| Chen L, Zhou C, Chen Q, Shang J, Liu Z, Guo Y, et al. Oncolytic Zika virus promotes intratumoral T cell infiltration and improves immunotherapy efficacy in glioblastoma. Mol Ther Oncolytics. 2022;24:522-534 pubmed 出版商
|
| Repáraz D, Ruiz M, Llopiz D, Silva L, Vercher E, Aparicio B, et al. Neoantigens as potential vaccines in hepatocellular carcinoma. J Immunother Cancer. 2022;10: pubmed 出版商
|
| Shiozawa S, Tsumiyama K, Miyazaki Y, Uto K, Sakurai K, Nakashima T, et al. DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus. iScience. 2022;25:103537 pubmed 出版商
|
| Li Y, Zhang N, Ma C, Xu W, Jin G, Zheng Y, et al. The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation. Cell Death Dis. 2021;12:1001 pubmed 出版商
|
| Forni M, Domínguez Amorocho O, de Assis L, Kinker G, Moraes M, Castrucci A, et al. An Immunometabolic Shift Modulates Cytotoxic Lymphocyte Activation During Melanoma Progression in TRPA1 Channel Null Mice. Front Oncol. 2021;11:667715 pubmed 出版商
|
| Christian L, Wang L, Lim B, Deng D, Wu H, Wang X, et al. Resident memory T cells in tumor-distant tissues fortify against metastasis formation. Cell Rep. 2021;35:109118 pubmed 出版商
|
| Yi W, Zhang Y, Liu B, Zhou Y, Liao D, Qiao X, et al. Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration. Cell Rep. 2021;34:108922 pubmed 出版商
|
| Delacher M, Simon M, Sanderink L, Hotz Wagenblatt A, Wuttke M, Schambeck K, et al. Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells. Immunity. 2021;54:702-720.e17 pubmed 出版商
|
| Gonzalez Figueroa P, Roco J, Papa I, Núñez Villacís L, Stanley M, Linterman M, et al. Follicular regulatory T cells produce neuritin to regulate B cells. Cell. 2021;184:1775-1789.e19 pubmed 出版商
|
| Zheng H, Zhang Y, Li L, Zhang R, Luo Z, Yang Z, et al. Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury. Front Cell Dev Biol. 2021;9:641527 pubmed 出版商
|
| Yi M, Zhang J, Li A, Niu M, Yan Y, Jiao Y, et al. The construction, expression, and enhanced anti-tumor activity of YM101: a bispecific antibody simultaneously targeting TGF-β and PD-L1. J Hematol Oncol. 2021;14:27 pubmed 出版商
|
| Zhou X, Zhu X, Li C, Li Y, Ye Z, Shapiro V, et al. Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity. Cell Rep. 2021;34:108601 pubmed 出版商
|
| Zhang Y, Dong X, Bai L, Shang X, Zeng Y. MUC1-induced immunosuppression in colon cancer can be reversed by blocking the PD1/PDL1 signaling pathway. Oncol Lett. 2020;20:317 pubmed 出版商
|
| Gong N, Zhang Y, Teng X, Wang Y, Huo S, Qing G, et al. Proton-driven transformable nanovaccine for cancer immunotherapy. Nat Nanotechnol. 2020;15:1053-1064 pubmed 出版商
|
| Yang W, Yu T, Huang X, Bilotta A, Xu L, Lu Y, et al. Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 2020;11:4457 pubmed 出版商
|
| Helfricht A, Thijssen P, Rother M, Shah R, Du L, Takada S, et al. Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome. J Exp Med. 2020;217: pubmed 出版商
|
| Van Den Eeckhout B, Van Hoecke L, Burg E, Van Lint S, Peelman F, Kley N, et al. Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant. NPJ Vaccines. 2020;5:64 pubmed 出版商
|
| Lin H, Wang Q, Liu L, Chen Z, Das R, Zhao Y, et al. Colonization of Mice With Amoxicillin-Associated Klebsiella variicola Drives Inflammation via Th1 Induction and Treg Inhibition. Front Microbiol. 2020;11:1256 pubmed 出版商
|
| Zhang Y, Chen C, Deng C, Zhang C, Li N, Wang Z, et al. A novel rabies vaccine based on infectious propagating particles derived from hybrid VEEV-Rabies replicon. EBioMedicine. 2020;56:102819 pubmed 出版商
|
| Bao Z, Li J, Zhang P, Pan Q, Liu B, Zhu J, et al. Toll-Like Receptor 3 Activator Preconditioning Enhances Modulatory Function of Adipose‑Derived Mesenchymal Stem Cells in a Fully MHC-Mismatched Murine Model of Heterotopic Heart Transplantation. Ann Transplant. 2020;25:e921287 pubmed 出版商
|
| Krotova K, Day A, Aslanidi G. An Engineered AAV6-Based Vaccine Induces High Cytolytic Anti-Tumor Activity by Directly Targeting DCs and Improves Ag Presentation. Mol Ther Oncolytics. 2019;15:166-177 pubmed 出版商
|
| Jackstadt R, van Hooff S, Leach J, Cortés Lavaud X, Lohuis J, Ridgway R, et al. Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis. Cancer Cell. 2019;36:319-336.e7 pubmed 出版商
|
| Misumi I, Cook K, Mitchell J, Lund M, Vick S, Lee R, et al. Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection. Cell Rep. 2019;27:1387-1396.e5 pubmed 出版商
|
| Fachi J, Felipe J, Pral L, da Silva B, Corrêa R, de Andrade M, et al. Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism. Cell Rep. 2019;27:750-761.e7 pubmed 出版商
|
| Srivastava S, Salter A, Liggitt D, Yechan Gunja S, Sarvothama M, Cooper K, et al. Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting. Cancer Cell. 2019;35:489-503.e8 pubmed 出版商
|
| Zhou J, Peng H, Li K, Qu K, Wang B, Wu Y, et al. Liver-Resident NK Cells Control Antiviral Activity of Hepatic T Cells via the PD-1-PD-L1 Axis. Immunity. 2019;50:403-417.e4 pubmed 出版商
|
| Cantor D, King B, Blumenberg L, Dimauro T, Aifantis I, Koralov S, et al. Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice. Cell Rep. 2019;26:108-118.e4 pubmed 出版商
|
| Zegarra Ruiz D, El Beidaq A, Iñiguez A, Lubrano Di Ricco M, Manfredo Vieira S, Ruff W, et al. A Diet-Sensitive Commensal Lactobacillus Strain Mediates TLR7-Dependent Systemic Autoimmunity. Cell Host Microbe. 2019;25:113-127.e6 pubmed 出版商
|
| Jin X, Ding D, Yan Y, Li H, Wang B, Ma L, et al. Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression. Mol Cell. 2019;73:22-35.e6 pubmed 出版商
|
| Kyburz A, Fallegger A, Zhang X, Altobelli A, Artola Borán M, Borbet T, et al. Transmaternal Helicobacter pylori exposure reduces allergic airway inflammation in offspring through regulatory T cells. J Allergy Clin Immunol. 2019;143:1496-1512.e11 pubmed 出版商
|
| Ogawa M, Inomata T, Shiang T, Tsubota K, Murakami A. Method for selective quantification of immune and inflammatory cells in the cornea using flow cytometry. J Biol Methods. 2018;5:e102 pubmed 出版商
|
| Uchimura T, Oyama Y, Deng M, Guo H, Wilson J, Rampanelli E, et al. The Innate Immune Sensor NLRC3 Acts as a Rheostat that Fine-Tunes T Cell Responses in Infection and Autoimmunity. Immunity. 2018;49:1049-1061.e6 pubmed 出版商
|
| Gilleron J, Bouget G, Ivanov S, Méziat C, Ceppo F, Vergoni B, et al. Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance. Cell Rep. 2018;25:3329-3341.e5 pubmed 出版商
|
| Graham D, Luo C, O Connell D, Lefkovith A, Brown E, Yassour M, et al. Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes. Nat Med. 2018;24:1762-1772 pubmed 出版商
|
| Wan X, Zinselmeyer B, Zakharov P, Vomund A, Taniguchi R, Santambrogio L, et al. Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides. Nature. 2018;560:107-111 pubmed 出版商
|
| Kim M, Galan C, Hill A, Wu W, Fehlner Peach H, Song H, et al. Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses. Immunity. 2018;49:151-163.e5 pubmed 出版商
|
| Barry K, Hsu J, Broz M, Cueto F, Binnewies M, Combes A, et al. A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments. Nat Med. 2018;24:1178-1191 pubmed 出版商
|
| Kagoya Y, Nakatsugawa M, Saso K, Guo T, Anczurowski M, Wang C, et al. DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models. Nat Commun. 2018;9:1915 pubmed 出版商
|
| Uribe Herranz M, Bittinger K, Rafail S, Guedan S, Pierini S, Tanes C, et al. Gut microbiota modulates adoptive cell therapy via CD8α dendritic cells and IL-12. JCI Insight. 2018;3: pubmed 出版商
|
| Wang L, Du F, Wang H, Xie C. Cooperation of CD4+ T cells and CD8+ T cells and release of IFN-γ are critical for antileukemia responses of recipient mice treated by microtransplantation. Exp Ther Med. 2018;15:1532-1537 pubmed 出版商
|
| Burton O, Tamayo J, Stranks A, Miller S, Koleoglou K, Weinberg E, et al. IgE promotes type 2 innate lymphoid cells in murine food allergy. Clin Exp Allergy. 2017;: pubmed 出版商
|
| Yuan X, Yang B, Dong Y, Yamamura A, Fu W. CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells. elife. 2017;6: pubmed 出版商
|
| Liao T, Xue Y, Zhao D, Li S, Liu M, Chen J, et al. In Vivo Attenuation of Antibody-Mediated Acute Renal Allograft Rejection by Ex Vivo TGF-?-Induced CD4+Foxp3+ Regulatory T Cells. Front Immunol. 2017;8:1334 pubmed 出版商
|
| Yeon S, Halim L, Chandele A, Perry C, Kim S, Kim S, et al. IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways. Sci Rep. 2017;7:11155 pubmed 出版商
|
| Kyburz A, Urban S, Altobelli A, Floess S, Huehn J, Cover T, et al. Helicobacter pylori and its secreted immunomodulator VacA protect against anaphylaxis in experimental models of food allergy. Clin Exp Allergy. 2017;47:1331-1341 pubmed 出版商
|
| Papa I, Saliba D, Ponzoni M, Bustamante S, Canete P, Gonzalez Figueroa P, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. 2017;547:318-323 pubmed 出版商
|
| Xu C, Ruan B, Jiang Y, Xue T, Wang Z, Lu H, et al. Antibiotics-induced gut microbiota dysbiosis promotes tumor initiation via affecting APC-Th1 development in mice. Biochem Biophys Res Commun. 2017;488:418-424 pubmed 出版商
|
| Inomata T, Hua J, Di Zazzo A, Dana R. Impaired Function of Peripherally Induced Regulatory T Cells in Hosts at High Risk of Graft Rejection. Sci Rep. 2016;6:39924 pubmed 出版商
|
| Wang Y, Jiang X, Zhu J, Dan Yue -, Zhang X, Wang X, et al. IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice. Sci Rep. 2016;6:31881 pubmed 出版商
|
| Mencarelli A, Cipriani S, Francisci D, Santucci L, Baldelli F, Distrutti E, et al. Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis. Sci Rep. 2016;6:30802 pubmed 出版商
|
| Campisi L, Barbet G, Ding Y, Esplugues E, Flavell R, Blander J. Apoptosis in response to microbial infection induces autoreactive TH17 cells. Nat Immunol. 2016;17:1084-92 pubmed 出版商
|
| Baptista M, Keszei M, Oliveira M, Sunahara K, Andersson J, Dahlberg C, et al. Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells. Nat Commun. 2016;7:12175 pubmed 出版商
|
| Deng Z, Rong Y, Teng Y, Zhuang X, Samykutty A, Mu J, et al. Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis. Oncogene. 2017;36:639-651 pubmed 出版商
|
| Chou T, Chuang Y, Hsieh W, Chang P, Liu H, Mo S, et al. Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1? for Th17 suppression. Nat Commun. 2016;7:11904 pubmed 出版商
|
| Sebastian M, Lopez Ocasio M, Metidji A, RIEDER S, Shevach E, Thornton A. Helios Controls a Limited Subset of Regulatory T Cell Functions. J Immunol. 2016;196:144-55 pubmed 出版商
|
| Spinner C, Uttenweiler Joseph S, Metais A, Stella A, Burlet Schiltz O, Moog Lutz C, et al. Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells. Sci Rep. 2015;5:16269 pubmed 出版商
|
| Richardson E, Shukla S, Nagy N, Boom W, Beck R, Zhou L, et al. ERK Signaling Is Essential for Macrophage Development. PLoS ONE. 2015;10:e0140064 pubmed 出版商
|
| Calderon B, Carrero J, Ferris S, Sojka D, Moore L, Epelman S, et al. The pancreas anatomy conditions the origin and properties of resident macrophages. J Exp Med. 2015;212:1497-512 pubmed 出版商
|
| Wiesner D, Specht C, Lee C, Smith K, Mukaremera L, Lee S, et al. Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. PLoS Pathog. 2015;11:e1004701 pubmed 出版商
|
| Sundberg T, Choi H, Song J, Russell C, Hussain M, Graham D, et al. Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells. Proc Natl Acad Sci U S A. 2014;111:12468-73 pubmed 出版商
|
| Lischke T, Heesch K, Schumacher V, Schneider M, Haag F, Koch Nolte F, et al. CD38 controls the innate immune response against Listeria monocytogenes. Infect Immun. 2013;81:4091-9 pubmed 出版商
|
| Siegmund K, Zeis T, Kunz G, Rolink T, Schaeren Wiemers N, Pieters J. Coronin 1-mediated naive T cell survival is essential for the development of autoimmune encephalomyelitis. J Immunol. 2011;186:3452-61 pubmed 出版商
|
| Rodriguez Manzanet R, Sanjuan M, Wu H, Quintana F, Xiao S, Anderson A, et al. T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice. Proc Natl Acad Sci U S A. 2010;107:8706-11 pubmed 出版商
|
| Zaborsky N, Brunner M, Wallner M, Himly M, Karl T, Schwarzenbacher R, et al. Antigen aggregation decides the fate of the allergic immune response. J Immunol. 2010;184:725-35 pubmed 出版商
|
| Shigeta A, Matsumoto M, Tedder T, Lowe J, Miyasaka M, Hirata T. An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation. Blood. 2008;112:4915-23 pubmed 出版商
|
| Matsumoto M, Shigeta A, Furukawa Y, Tanaka T, Miyasaka M, Hirata T. CD43 collaborates with P-selectin glycoprotein ligand-1 to mediate E-selectin-dependent T cell migration into inflamed skin. J Immunol. 2007;178:2499-506 pubmed
|
| Leon Ponte M, Ahern G, O Connell P. Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor. Blood. 2007;109:3139-46 pubmed
|