产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
PE/Cyanine5抗小鼠CD8a
目录 :
100709
规格 :
25微克
价格 :
77美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE-Cy5
克隆名称 :
53-6.7
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 52
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 2a
Pereira J, Cavaco P, da Silva R, Pacheco Leyva I, Mereiter S, Pinto R, et al. P-selectin glycoprotein ligand 1 promotes T cell lymphoma development and dissemination. Transl Oncol. 2021;14:101125 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Petty A, Dai R, Lapalombella R, Baiocchi R, Benson D, Li Z, et al. Hedgehog-induced PD-L1 on tumor-associated macrophages is critical for suppression of tumor-infiltrating CD8+ T cell function. JCI Insight. 2021;6: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4
Shikama Y, Kurosawa M, Furukawa M, Ishimaru N, Matsushita K. Involvement of adiponectin in age-related increases in tear production in mice. Aging (Albany NY). 2019;11:8329-8346 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4b
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Kurosawa M, Shikama Y, Furukawa M, Arakaki R, Ishimaru N, Matsushita K. Chemokines Up-Regulated in Epithelial Cells Control Senescence-Associated T Cell Accumulation in Salivary Glands of Aged and Sjögren's Syndrome Model Mice. Int J Mol Sci. 2021;22: pubmed 出版商
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Zhang H, Alsaleh G, Feltham J, Sun Y, Napolitano G, Riffelmacher T, et al. Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. Mol Cell. 2019;76:110-125.e9 pubmed 出版商
Luck H, Khan S, Kim J, Copeland J, Revelo X, Tsai S, et al. Gut-associated IgA+ immune cells regulate obesity-related insulin resistance. Nat Commun. 2019;10:3650 pubmed 出版商
Tomay F, Marinelli A, Leoni V, Caccia C, Matros A, Mock H, et al. Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice. J Transl Med. 2019;17:237 pubmed 出版商
Di Genua C, Norfo R, Rodriguez Meira A, Wen W, Drissen R, Booth C, et al. Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation. Haematologica. 2019;: pubmed 出版商
Tzelepis K, De Braekeleer E, Aspris D, Barbieri I, Vijayabaskar M, Liu W, et al. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nat Commun. 2018;9:5378 pubmed 出版商
Sade Feldman M, Yizhak K, Bjorgaard S, Ray J, de Boer C, Jenkins R, et al. Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma. Cell. 2018;175:998-1013.e20 pubmed 出版商
Tsai S, Clemente Casares X, Zhou A, Lei H, Ahn J, Chan Y, et al. Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection. Cell Metab. 2018;28:922-934.e4 pubmed 出版商
Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights A, et al. UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Nat Genet. 2018;50:883-894 pubmed 出版商
Booth C, Barkas N, Neo W, Boukarabila H, Soilleux E, Giotopoulos G, et al. Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors. Cancer Cell. 2018;33:274-291.e8 pubmed 出版商
Sharma P, Dmitriev I, Kashentseva E, Raes G, Li L, Kim S, et al. Development of an adenovirus vector vaccine platform for targeting dendritic cells. Cancer Gene Ther. 2018;25:27-38 pubmed 出版商
Liang Z, Zhang L, Su H, Luan R, Na N, Sun L, et al. MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance. Autophagy. 2017;: pubmed 出版商
Hart B, Lee S. Overexpression of a Mycobacterium ulcerans Ag85B-EsxH Fusion Protein in Recombinant BCG Improves Experimental Buruli Ulcer Vaccine Efficacy. PLoS Negl Trop Dis. 2016;10:e0005229 pubmed 出版商
Sim S, Kim J, Seong B, Nguyen H, Chang J. Baculovirus Displaying Hemagglutinin Elicits Broad Cross-Protection against Influenza in Mice. PLoS ONE. 2016;11:e0152485 pubmed 出版商
Sun L, Sun C, Liang Z, Li H, Chen L, Luo H, et al. FSP1(+) fibroblast subpopulation is essential for the maintenance and regeneration of medullary thymic epithelial cells. Sci Rep. 2015;5:14871 pubmed 出版商
Hart B, Hale L, Lee S. Recombinant BCG Expressing Mycobacterium ulcerans Ag85A Imparts Enhanced Protection against Experimental Buruli ulcer. PLoS Negl Trop Dis. 2015;9:e0004046 pubmed 出版商
Luck H, Tsai S, Chung J, Clemente Casares X, Ghazarian M, Revelo X, et al. Regulation of obesity-related insulin resistance with gut anti-inflammatory agents. Cell Metab. 2015;21:527-42 pubmed 出版商
Cui L, Osada K, Imaizumi A, Kataoka K, Nakano K. Feasibility of a subcutaneously administered block/homo-mixed polyplex micelle as a carrier for DNA vaccination in a mouse tumor model. J Control Release. 2015;206:220-31 pubmed 出版商
Naik A, Hawwari A, Krangel M. Specification of Vδ and Vα usage by Tcra/Tcrd locus V gene segment promoters. J Immunol. 2015;194:790-4 pubmed 出版商
Revelo X, Tsai S, Lei H, Luck H, Ghazarian M, Tsui H, et al. Perforin is a novel immune regulator of obesity-related insulin resistance. Diabetes. 2015;64:90-103 pubmed 出版商
Ma P, Jiang J, Gao C, Cheng P, Li J, Huang X, et al. Immunosuppressive effect of compound K on islet transplantation in an STZ-induced diabetic mouse model. Diabetes. 2014;63:3458-69 pubmed 出版商
Gungor B, Yagci F, Tincer G, Bayyurt B, Alpdundar E, Yildiz S, et al. CpG ODN nanorings induce IFN? from plasmacytoid dendritic cells and demonstrate potent vaccine adjuvant activity. Sci Transl Med. 2014;6:235ra61 pubmed 出版商
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Britschgi M, Link A, Lissandrin T, Luther S. Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo. J Immunol. 2008;181:7681-8 pubmed
Kingeter L, Schaefer B. Loss of protein kinase C theta, Bcl10, or Malt1 selectively impairs proliferation and NF-kappa B activation in the CD4+ T cell subset. J Immunol. 2008;181:6244-54 pubmed
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Jordan J, Woods M, Olano J, Walker D. The absence of Toll-like receptor 4 signaling in C3H/HeJ mice predisposes them to overwhelming rickettsial infection and decreased protective Th1 responses. Infect Immun. 2008;76:3717-24 pubmed 出版商
Guo Y, Maillard I, Chakraborti S, Rothenberg E, Speck N. Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification. Blood. 2008;112:480-92 pubmed 出版商
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产品信息
抗原 :
CD8a
Apps. Abbrev. :
流式细胞仪
目录 :
100709
克隆 :
53-6.7
产品 :
PE/Cyanine5抗小鼠CD8a
抗体亚型 :
Rat IgG2a, κ
其他名称 :
T8, Lyt2, Ly-2
规格 :
25微克
价格(美元) :
77美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PE_CYANINE5
免疫原 :
小鼠胸腺或脾脏
应用注释 :
Clone 53-6.7 antibody competes with clone 5H10-1 antibody for binding to thymocytes 3 . The 53-6.7 antibody has been reported to block antigen presentation via MHC class I and inhibit T cell responses to IL-2. This antibody has also been used for depletion of CD8a + cells. Additional reported applications (for the relevant formats) include: immunoprecipitation 1,3 , in vivo and in vitro cell depletion 2,10,15 , inhibition of CD8 T cell proliferation 3 , blocking of cytotoxicity 3,4 , immunohistochemical staining 5,6 of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections, and spatial biology (IBEX) 29,30 . Clone 53-6.7 is not recommended for immunohistochemistry of formalin-fixed paraffin sections. The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays or in vivo studies (Cat No. 100746).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。