产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
亮紫色510™抗小鼠CD8a
目录 :
100751
规格 :
125微升
价格 :
165美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
BV510
克隆名称 :
53-6.7
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 75
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 s3
Barker K, Etesami N, Shenoy A, Arafa E, Lyon de Ana C, Smith N, et al. Lung-resident memory B cells protect against bacterial pneumonia. J Clin Invest. 2021;131: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4d
Clemen R, Freund E, Mrochen D, Miebach L, Schmidt A, Rauch B, et al. Gas Plasma Technology Augments Ovalbumin Immunogenicity and OT-II T Cell Activation Conferring Tumor Protection in Mice. Adv Sci (Weinh). 2021;8:2003395 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1s3, 4c
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  • 流式细胞仪; 小鼠; 图 2d
Bekeschus S, Clemen R, Nießner F, Sagwal S, Freund E, Schmidt A. Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion. Adv Sci (Weinh). 2020;7:1903438 pubmed 出版商
  • 流式细胞仪; 小鼠; 2.5 ug/ml; 图 s4
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  • 流式细胞仪; 小鼠; 图 5a
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Aegerter H, Kulikauskaite J, Crotta S, Patel H, Kelly G, Hessel E, et al. Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection. Nat Immunol. 2020;21:145-157 pubmed 出版商
Ge C, Monk I, Pizzolla A, Wang N, Bedford J, Stinear T, et al. Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment. Cell Rep. 2019;29:4236-4244.e3 pubmed 出版商
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Schaftenaar F, Amersfoort J, Douna H, Kröner M, Foks A, Bot I, et al. Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model. Sci Rep. 2019;9:17391 pubmed 出版商
Mao W, Ghasemzadeh A, Freeman Z, Obradovic A, Chaimowitz M, Nirschl T, et al. Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition. J Immunother Cancer. 2019;7:277 pubmed 出版商
Bradley K, Finsterbusch K, Schnepf D, Crotta S, Llorian M, Davidson S, et al. Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection. Cell Rep. 2019;28:245-256.e4 pubmed 出版商
Bommareddy P, Lowe D, Kaufman H, Rabkin S, Saha D. Multi-parametric flow cytometry staining procedure for analyzing tumor-infiltrating immune cells following oncolytic herpes simplex virus immunotherapy in intracranial glioblastoma. J Biol Methods. 2019;6: pubmed
Matsuoka S, Hashimoto D, Kadowaki M, Ohigashi H, Hayase E, Yokoyama E, et al. The myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease. Haematologica. 2019;: pubmed 出版商
Li S, Sen S, Schneider J, Xiong K, Nusbacher N, Moreno Huizar N, et al. Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection. PLoS Pathog. 2019;15:e1007611 pubmed 出版商
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Zhang L, Chen S, Guerrero Juarez C, Li F, Tong Y, Liang Y, et al. Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta. Immunity. 2019;50:121-136.e5 pubmed 出版商
Kyburz A, Fallegger A, Zhang X, Altobelli A, Artola Borán M, Borbet T, et al. Transmaternal Helicobacter pylori exposure reduces allergic airway inflammation in offspring through regulatory T cells. J Allergy Clin Immunol. 2019;143:1496-1512.e11 pubmed 出版商
Fowler A, Tang W, Young M, Mamidi A, Viramontes K, McCauley M, et al. Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice. Cell Host Microbe. 2018;24:743-750.e5 pubmed 出版商
Urata S, Kenyon E, Nayak D, Cubitt B, Kurosaki Y, Yasuda J, et al. BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection. PLoS Pathog. 2018;14:e1007172 pubmed 出版商
Lino A, Dang V, Lampropoulou V, Welle A, Joedicke J, Pohar J, et al. LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells. Immunity. 2018;49:120-133.e9 pubmed 出版商
Moore M, Blachere N, Fak J, Park C, Sawicka K, Parveen S, et al. ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity. elife. 2018;7: pubmed 出版商
Wang D, Diao H, Getzler A, Rogal W, Frederick M, Milner J, et al. The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation. Immunity. 2018;48:659-674.e6 pubmed 出版商
Herndler Brandstetter D, Ishigame H, Shinnakasu R, Plajer V, Stecher C, Zhao J, et al. KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity. Immunity. 2018;48:716-729.e8 pubmed 出版商
Hiramoto T, Li L, Funk S, Hirata R, Russell D. Nuclease-free Adeno-Associated Virus-Mediated Il2rg Gene Editing in X-SCID Mice. Mol Ther. 2018;26:1255-1265 pubmed 出版商
Zhu D, Tan J, Maleken A, Muljadi R, Chan S, Lau S, et al. Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury. Stem Cell Res Ther. 2017;8:257 pubmed 出版商
Jenkins R, Aref A, Lizotte P, Ivanova E, Stinson S, Zhou C, et al. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discov. 2018;8:196-215 pubmed 出版商
Soukup K, Halfmann A, Dillinger B, Poyer F, Martin K, Blauensteiner B, et al. Loss of MAPK-activated protein kinase 2 enables potent dendritic cell-driven anti-tumour T cell response. Sci Rep. 2017;7:11746 pubmed 出版商
Cosway E, LUCAS B, James K, Parnell S, Carvalho Gaspar M, White A, et al. Redefining thymus medulla specialization for central tolerance. J Exp Med. 2017;214:3183-3195 pubmed 出版商
Saha D, Martuza R, Rabkin S. Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade. Cancer Cell. 2017;32:253-267.e5 pubmed 出版商
Kyburz A, Urban S, Altobelli A, Floess S, Huehn J, Cover T, et al. Helicobacter pylori and its secreted immunomodulator VacA protect against anaphylaxis in experimental models of food allergy. Clin Exp Allergy. 2017;47:1331-1341 pubmed 出版商
Telford W, Stickland L, Koschorreck M. Ultraviolet 320 nm laser excitation for flow cytometry. Cytometry A. 2017;91:314-325 pubmed 出版商
Rodriguez Ruiz M, Rodríguez I, Garasa S, Barbés B, Solorzano J, Perez Gracia J, et al. Abscopal Effects of Radiotherapy Are Enhanced by Combined Immunostimulatory mAbs and Are Dependent on CD8 T Cells and Crosspriming. Cancer Res. 2016;76:5994-6005 pubmed
Wang C, Liu X, Li Z, Chai Y, Jiang Y, Wang Q, et al. CD8(+)NKT-like cells regulate the immune response by killing antigen-bearing DCs. Sci Rep. 2015;5:14124 pubmed 出版商
Mairhofer D, Ortner D, Tripp C, Schaffenrath S, Fleming V, Heger L, et al. Impaired gp100-Specific CD8(+) T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma Model. J Invest Dermatol. 2015;135:2785-2793 pubmed 出版商
Cui L, Osada K, Imaizumi A, Kataoka K, Nakano K. Feasibility of a subcutaneously administered block/homo-mixed polyplex micelle as a carrier for DNA vaccination in a mouse tumor model. J Control Release. 2015;206:220-31 pubmed 出版商
Wang T, Zhan X, Bu C, Lyon S, Pratt D, Hildebrand S, et al. Real-time resolution of point mutations that cause phenovariance in mice. Proc Natl Acad Sci U S A. 2015;112:E440-9 pubmed 出版商
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Lee C, Chiang Y, Chang S, Chong C, Cheng B, Roffler S. Tumor-localized ligation of CD3 and CD28 with systemic regulatory T-cell depletion induces potent innate and adaptive antitumor responses. Clin Cancer Res. 2009;15:2756-66 pubmed 出版商
Britschgi M, Link A, Lissandrin T, Luther S. Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo. J Immunol. 2008;181:7681-8 pubmed
Kingeter L, Schaefer B. Loss of protein kinase C theta, Bcl10, or Malt1 selectively impairs proliferation and NF-kappa B activation in the CD4+ T cell subset. J Immunol. 2008;181:6244-54 pubmed
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Jordan J, Woods M, Olano J, Walker D. The absence of Toll-like receptor 4 signaling in C3H/HeJ mice predisposes them to overwhelming rickettsial infection and decreased protective Th1 responses. Infect Immun. 2008;76:3717-24 pubmed 出版商
Guo Y, Maillard I, Chakraborti S, Rothenberg E, Speck N. Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification. Blood. 2008;112:480-92 pubmed 出版商
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Ko S, Ko H, Chang W, Park S, Kweon M, Kang C. alpha-Galactosylceramide can act as a nasal vaccine adjuvant inducing protective immune responses against viral infection and tumor. J Immunol. 2005;175:3309-17 pubmed
产品信息
抗原 :
CD8a
Apps. Abbrev. :
流式细胞仪
目录 :
100751
克隆 :
53-6.7
产品 :
亮紫色510™抗小鼠CD8a
抗体亚型 :
Rat IgG2a, κ
其他名称 :
T8, Lyt2, Ly-2
规格 :
125微升
价格(美元) :
165美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
BV510
免疫原 :
小鼠胸腺或脾脏
应用注释 :
Clone 53-6.7 antibody competes with clone 5H10-1 antibody for binding to thymocytes 3 . The 53-6.7 antibody has been reported to block antigen presentation via MHC class I and inhibit T cell responses to IL-2. This antibody has also been used for depletion of CD8a + cells. Additional reported applications (for the relevant formats) include: immunoprecipitation 1,3 , in vivo and in vitro cell depletion 2,10,15 , inhibition of CD8 T cell proliferation 3 , blocking of cytotoxicity 3,4 , immunohistochemical staining 5,6 of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections, and spatial biology (IBEX) 29,30 . Clone 53-6.7 is not recommended for immunohistochemistry of formalin-fixed paraffin sections. The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays or in vivo studies (Cat No. 100746).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。