产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Pacific Blue™ anti-mouse/human CD11b
目录 :
101224
规格 :
100微克
价格 :
195美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
Pacific Blue荧光染料
克隆名称 :
M1/70
反应物种 :
人类, 小鼠, 黑猩猩
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 109
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:200; 图 1a, 6a, 6s1a, 7s1a
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  • 流式细胞仪; 小鼠; 1:400; 图 s10g
Terashima Y, Toda E, Itakura M, Otsuji M, Yoshinaga S, Okumura K, et al. Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties. Nat Commun. 2020;11:609 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Tomlinson J, Žygelytė E, Grenier J, Edwards M, Cheetham J. Temporal changes in macrophage phenotype after peripheral nerve injury. J Neuroinflammation. 2018;15:185 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 s1d
Kumar B, Garcia M, Weng L, Jung X, Murakami J, Hu X, et al. Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion. Leukemia. 2018;32:575-587 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s2a
von Moltke J, O Leary C, Barrett N, Kanaoka Y, Austen K, Locksley R. Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. J Exp Med. 2017;214:27-37 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4
Yang Y, Xu J, Chen H, Fei X, Tang Y, Yan Y, et al. MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells. Oncotarget. 2016;7:17520-31 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Tsaousi A, Hayes E, Di Gregoli K, Bond A, Bevan L, Thomas A, et al. Plaque Size Is Decreased but M1 Macrophage Polarization and Rupture Related Metalloproteinase Expression Are Maintained after Deleting T-Bet in ApoE Null Mice. PLoS ONE. 2016;11:e0148873 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Pannu J, Belle J, Forster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Baillet A, Rehaume L, Benham H, O Meara C, Armitage C, Ruscher R, et al. High Chlamydia Burden Promotes Tumor Necrosis Factor-Dependent Reactive Arthritis in SKG Mice. Arthritis Rheumatol. 2015;67:1535-47 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
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  • 流式细胞仪; 小鼠; 图 1
Adamopoulos I, Suzuki E, Chao C, Gorman D, Adda S, Maverakis E, et al. IL-17A gene transfer induces bone loss and epidermal hyperplasia associated with psoriatic arthritis. Ann Rheum Dis. 2015;74:1284-92 pubmed 出版商
  • 流式细胞仪; 小鼠
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Díaz Salazar C, Sun J. Coordinated Viral Control by Cytotoxic Lymphocytes Ensures Optimal Adaptive NK Cell Responses. Cell Rep. 2020;32:108186 pubmed 出版商
Michael B, Bricio Moreno L, Sorensen E, Miyabe Y, Lian J, Solomon T, et al. Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis. Cell Rep. 2020;32:108150 pubmed 出版商
Nguyen G, Shaban L, Mack M, Swanson K, Bunnell S, Sykes D, et al. SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst. elife. 2020;9: pubmed 出版商
Yeung F, Chen Y, Lin J, Leung J, McCauley C, Devlin J, et al. Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization. Cell Host Microbe. 2020;27:809-822.e6 pubmed 出版商
Brenner E, Schörg B, Ahmetlić F, Wieder T, Hilke F, Simon N, et al. Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours. Nat Commun. 2020;11:1335 pubmed 出版商
Cheng Y, Luo H, Izzo F, Pickering B, Nguyen D, Myers R, et al. m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment. Cell Rep. 2019;28:1703-1716.e6 pubmed 出版商
Tomida S, Aizawa K, Nishida N, Aoki H, Imai Y, Nagai R, et al. Indomethacin reduces rates of aortic dissection and rupture of the abdominal aorta by inhibiting monocyte/macrophage accumulation in a murine model. Sci Rep. 2019;9:10751 pubmed 出版商
Yahagi A, Saika T, Hirano H, Takai Imamura M, Tsuji F, Aono H, et al. IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis. RMD Open. 2019;5:e000853 pubmed 出版商
Hou X, Chen G, Bracamonte Baran W, Choi H, Diny N, Sung J, et al. The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis. Cell Rep. 2019;28:172-189.e7 pubmed 出版商
Rothweiler S, Feldbrügge L, Jiang Z, Csizmadia E, Longhi M, Vaid K, et al. Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis. Purinergic Signal. 2019;15:375-385 pubmed 出版商
Kubli S, Vornholz L, Duncan G, Zhou W, Ramachandran P, Fortin J, et al. Fcmr regulates mononuclear phagocyte control of anti-tumor immunity. Nat Commun. 2019;10:2678 pubmed 出版商
Paris J, Morgan M, Campos J, Spencer G, Shmakova A, Ivanova I, et al. Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia. Cell Stem Cell. 2019;: pubmed 出版商
Choi H, Deng J, Li S, Silk T, Dong L, Brea E, et al. Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer. Cell Rep. 2019;27:806-819.e5 pubmed 出版商
Matsumura T, Ikebe T, Arikawa K, Hosokawa M, Aiko M, Iguchi A, et al. Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice. Cell Rep. 2019;27:561-571.e6 pubmed 出版商
Bijalwan M, Young C, Tingling J, Zhou X, Rimmelin A, Leibowitz J, et al. Characterization of Plaque-Sized Variants of Daniel's (DA) Strain in Theiler's Virus-Induced Epilepsy. Sci Rep. 2019;9:3444 pubmed 出版商
Dahlgren M, Jones S, Cautivo K, Dubinin A, Ortiz Carpena J, Farhat S, et al. Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches. Immunity. 2019;50:707-722.e6 pubmed 出版商
Zhao J, Wen X, Tian L, Li T, Xu C, Wen X, et al. Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer. Nat Commun. 2019;10:899 pubmed 出版商
Arora H, Wilcox S, Johnson L, Munro L, Eyford B, Pfeifer C, et al. The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock. Immunity. 2019;50:418-431.e6 pubmed 出版商
Fang E, Hou Y, Palikaras K, Adriaanse B, Kerr J, Yang B, et al. Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease. Nat Neurosci. 2019;22:401-412 pubmed 出版商
Ren S, Chen X, Huang R, Zhou G, Yuan Z. SOCS4 expressed by recombinant HSV protects against cytokine storm in a mouse model. Oncol Rep. 2019;41:1509-1520 pubmed 出版商
Park S, Cho H, Thornton A, Barlowe T, Chou T, Chhangawala S, et al. IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation. Cell Stem Cell. 2019;24:153-165.e7 pubmed 出版商
Uhl J, Gujarathi S, Waheed A, Gordon A, Freed E, Gousset K. Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes. J Cell Commun Signal. 2019;13:209-224 pubmed 出版商
Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, et al. Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression. Nat Commun. 2018;9:4832 pubmed 出版商
Zhu H, Zhang L, Wu Y, Dong B, Guo W, Wang M, et al. T-ALL leukemia stem cell 'stemness' is epigenetically controlled by the master regulator SPI1. elife. 2018;7: pubmed 出版商
Fatkhullina A, Peshkova I, Dzutsev A, Aghayev T, McCulloch J, Thovarai V, et al. An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis. Immunity. 2018;49:943-957.e9 pubmed 出版商
Hong S, Zhang Z, Liu H, Tian M, Zhu X, Zhang Z, et al. B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen. Immunity. 2018;49:695-708.e4 pubmed 出版商
Malik A, Sharma D, Malireddi R, Guy C, Chang T, Olsen S, et al. SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer. Immunity. 2018;49:515-530.e5 pubmed 出版商
Geary C, Krishna C, Lau C, Adams N, Gearty S, Pritykin Y, et al. Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection. Cell Rep. 2018;24:1949-1957.e6 pubmed 出版商
Lino A, Dang V, Lampropoulou V, Welle A, Joedicke J, Pohar J, et al. LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells. Immunity. 2018;49:120-133.e9 pubmed 出版商
Young J, Yin D, Vannier A, Alegre M, Chong A. Equal Expansion of Endogenous Transplant-Specific Regulatory T Cell and Recruitment Into the Allograft During Rejection and Tolerance. Front Immunol. 2018;9:1385 pubmed 出版商
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Silver A, Buckley S, Hughes M, Hastings A, Nitabach M, Fikrig E. Daily oscillations in expression and responsiveness of Toll-like receptors in splenic immune cells. Heliyon. 2018;4:e00579 pubmed 出版商
Adams N, Lau C, Fan X, Rapp M, Geary C, Weizman O, et al. Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response. Immunity. 2018;48:1172-1182.e6 pubmed 出版商
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Si Y, Wen Y, Kelly S, Chong A, Collier J. Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses. J Control Release. 2018;282:120-130 pubmed 出版商
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Cao W, Kayama H, Chen M, Delmas A, Sun A, Kim S, et al. The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids. Immunity. 2017;47:1182-1196.e10 pubmed 出版商
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Yuan X, Yang B, Dong Y, Yamamura A, Fu W. CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells. elife. 2017;6: pubmed 出版商
Clemente Casares X, Hosseinzadeh S, Barbu I, Dick S, Macklin J, Wang Y, et al. A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis. Immunity. 2017;47:974-989.e8 pubmed 出版商
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Grayczyk J, Harvey C, Laczkovich I, Alonzo F. A Lipoylated Metabolic Protein Released by Staphylococcus aureus Suppresses Macrophage Activation. Cell Host Microbe. 2017;22:678-687.e9 pubmed 出版商
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Chandra J, Kuo P, Hahn A, Belz G, Frazer I. Batf3 selectively determines acquisition of CD8+ dendritic cell phenotype and function. Immunol Cell Biol. 2017;95:215-223 pubmed 出版商
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Fournier M, Lebert Ghali C, Bijl J. HOXA4 provides stronger engraftment potential to short-term repopulating cells than HOXB4. Stem Cells Dev. 2015;24:2413-22 pubmed 出版商
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Watson N, Schneider K, Massa P. SHP-1-dependent macrophage differentiation exacerbates virus-induced myositis. J Immunol. 2015;194:2796-809 pubmed 出版商
Price P, Bánki Z, Scheideler A, Stoiber H, Verschoor A, Sutter G, et al. Complement component C5 recruits neutrophils in the absence of C3 during respiratory infection with modified vaccinia virus Ankara. J Immunol. 2015;194:1164-8 pubmed 出版商
Chen S, Wang L, Fan J, Ye C, Dominguez D, Zhang Y, et al. Host miR155 promotes tumor growth through a myeloid-derived suppressor cell-dependent mechanism. Cancer Res. 2015;75:519-31 pubmed 出版商
Nacer A, Movila A, Sohet F, Girgis N, Gundra U, Loke P, et al. Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier. PLoS Pathog. 2014;10:e1004528 pubmed 出版商
Ashok A, Rai N, Tripathi S, Bandyopadhyay S. Exposure to As-, Cd-, and Pb-mixture induces Aβ, amyloidogenic APP processing and cognitive impairments via oxidative stress-dependent neuroinflammation in young rats. Toxicol Sci. 2015;143:64-80 pubmed 出版商
Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, et al. Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses. elife. 2014;3:e04177 pubmed 出版商
Endo J, Sano M, Isobe Y, Fukuda K, Kang J, Arai H, et al. 18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload-induced maladaptive cardiac remodeling. J Exp Med. 2014;211:1673-87 pubmed 出版商
Ni P, Solomon B, Hsieh C, Allen P, Morris G. The ability to rearrange dual TCRs enhances positive selection, leading to increased Allo- and Autoreactive T cell repertoires. J Immunol. 2014;193:1778-86 pubmed 出版商
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Weber G, Chousterman B, Hilgendorf I, Robbins C, Theurl I, Gerhardt L, et al. Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. J Exp Med. 2014;211:1243-56 pubmed 出版商
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Sharma A, Steichen A, Jondle C, Mishra B, Sharma J. Protective role of Mincle in bacterial pneumonia by regulation of neutrophil mediated phagocytosis and extracellular trap formation. J Infect Dis. 2014;209:1837-46 pubmed 出版商
Raines A, Adam M, Magella B, Meyer S, Grimes H, Dey S, et al. Recombineering-based dissection of flanking and paralogous Hox gene functions in mouse reproductive tracts. Development. 2013;140:2942-52 pubmed 出版商
Janelsins B, Sumpter T, Tkacheva O, Rojas Canales D, Erdos G, Mathers A, et al. Neurokinin-1 receptor agonists bias therapeutic dendritic cells to induce type 1 immunity by licensing host dendritic cells to produce IL-12. Blood. 2013;121:2923-33 pubmed 出版商
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Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed 出版商
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产品信息
抗原 :
CD11b
Apps. Abbrev. :
流式细胞仪
目录 :
101224
克隆 :
M1/70
产品 :
Pacific Blue™ anti-mouse/human CD11b
抗体亚型 :
Rat IgG2b, κ
其他名称 :
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
规格 :
100微克
价格(美元) :
195美元
反应物种 :
Mouse, Human, Cross-Reactivity: Cynomolgus, Rhesus, Baboon, Chimpanzee,Rabbit (Lapine)
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PB
免疫原 :
C57BL/10 splenocytes
应用注释 :
Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F). Additional reported applications (for relevant formats of this clone) include: immunoprecipitation 1,4 , in vitro blocking 3,9,12 , depletion 2,8 , immunofluorescence microscopy 6,7,10 , and immunohistochemistry of acetone-fixed frozen sections 5,11-13 . For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。