产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
亮紫色421™抗小鼠/人类CD11b
目录 :
101235
规格 :
125微升
价格 :
165美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
BV421
克隆名称 :
M1/70
反应物种 :
人类, 小鼠
应用 :
免疫组化, 流式细胞仪
更多信息或购买 :
文章摘录数: 81
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 4f
Lin J, Lv J, Yu S, Chen Y, Wang H, Chen J. Transcript Engineered Extracellular Vesicles Alleviate Alloreactive Dynamics in Renal Transplantation. Adv Sci (Weinh). 2022;9:e2202633 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s3a
Yang C, Lei L, Collins J, Briones M, Ma L, Sturdevant G, et al. Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor. Nat Commun. 2021;12:5454 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 9e
Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, et al. The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II. Nat Commun. 2021;12:3333 pubmed 出版商
  • 流式细胞仪; 小鼠
Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton K, Tian L, et al. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021;125:176-189 pubmed 出版商
  • 免疫组化; 小鼠; 图 s1b
Cho C, Smallwood P, Nathans J. Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation. Neuron. 2017;95:1056-1073.e5 pubmed 出版商
  • 流式细胞仪; 人类; 图 2
Chai Y, Lee E, Gubbe J, Brekke J. 3D Cell Culture in a Self-Assembled Nanofiber Environment. PLoS ONE. 2016;11:e0162853 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:1000; 图 9
Menheniott T, O Connor L, Chionh Y, Däbritz J, Scurr M, Rollo B, et al. Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression. J Clin Invest. 2016;126:1383-400 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:1000; 图 8a
Däbritz J, Judd L, Chalinor H, Menheniott T, Giraud A. Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived suppressor cells. Sci Rep. 2016;6:20584 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
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  • 流式细胞仪; 小鼠
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Alikhanyan K, Chen Y, Somogyi K, Kraut S, Sotillo R. Mad2 Induced Aneuploidy Contributes to Eml4-Alk Driven Lung Cancer by Generating an Immunosuppressive Environment. Cancers (Basel). 2021;13: pubmed 出版商
Bae S, Park P, Lee Y, Mun S, Giannopoulou E, Fujii T, et al. MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages. Cell Rep. 2021;35:109264 pubmed 出版商
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Singh S, Thompson J, Yilmaz B, Li H, Weis S, Sobral D, et al. Loss of α-gal during primate evolution enhanced antibody-effector function and resistance to bacterial sepsis. Cell Host Microbe. 2021;29:347-361.e12 pubmed 出版商
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Chen M, Yang A, Yousef H, Lee D, Chen W, Schaum N, et al. Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues. Cell Rep. 2020;30:4418-4432.e4 pubmed 出版商
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Krivtsov A, Evans K, Gadrey J, Eschle B, Hatton C, Uckelmann H, et al. A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia. Cancer Cell. 2019;36:660-673.e11 pubmed 出版商
Qi F, Liu M, Li F, Lv Q, Wang G, Gong S, et al. Interleukin-37 Ameliorates Influenza Pneumonia by Attenuating Macrophage Cytokine Production in a MAPK-Dependent Manner. Front Microbiol. 2019;10:2482 pubmed 出版商
O CONNOR T, Zhou X, Kosla J, Adili A, García Beccaria M, Kotsiliti E, et al. Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention. Cancer Cell. 2019;36:250-267.e9 pubmed 出版商
Di Mitri D, Mirenda M, Vasilevska J, Calcinotto A, Delaleu N, Revandkar A, et al. Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer. Cell Rep. 2019;28:2156-2168.e5 pubmed 出版商
Hou X, Chen G, Bracamonte Baran W, Choi H, Diny N, Sung J, et al. The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis. Cell Rep. 2019;28:172-189.e7 pubmed 出版商
Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, et al. Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors. Cell. 2019;178:346-360.e24 pubmed 出版商
Rashidi M, Simpson D, Hempel A, Frank D, Petrie E, Vince A, et al. The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release. J Immunol. 2019;: pubmed 出版商
Bryson B, Rosebrock T, Tafesse F, Itoh C, Nibasumba A, Babunovic G, et al. Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis. Nat Commun. 2019;10:2329 pubmed 出版商
Yousef H, Czupalla C, Lee D, Chen M, Burke A, Zera K, et al. Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1. Nat Med. 2019;25:988-1000 pubmed 出版商
Yousef H, Czupalla C, Lee D, Butcher E, Wyss Coray T. Papain-based Single Cell Isolation of Primary Murine Brain Endothelial Cells Using Flow Cytometry. Bio Protoc. 2018;8: pubmed 出版商
Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, et al. Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells. Sci Rep. 2019;9:6136 pubmed 出版商
Hirai T, Zenke Y, Yang Y, Bartholin L, Beura L, Masopust D, et al. Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells. Immunity. 2019;50:1249-1261.e5 pubmed 出版商
Liu J, Zhang X, Chen K, Cheng Y, Liu S, Xia M, et al. CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis. Immunity. 2019;50:600-615.e15 pubmed 出版商
Li Q, Cheng Z, Zhou L, Darmanis S, Neff N, Okamoto J, et al. Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing. Neuron. 2019;101:207-223.e10 pubmed 出版商
Buzzelli J, O Connor L, Scurr M, Chung Nien Chin S, Catubig A, Ng G, et al. Overexpression of IL-11 promotes premalignant gastric epithelial hyperplasia in isolation from germline gp130-JAK-STAT driver mutations. Am J Physiol Gastrointest Liver Physiol. 2019;316:G251-G262 pubmed 出版商
Grzelak A, Polakova I, Smahelova J, Vackova J, Pekarčíková L, Tachezy R, et al. Experimental Combined Immunotherapy of Tumours with Major Histocompatibility Complex Class I Downregulation. Int J Mol Sci. 2018;19: pubmed 出版商
Li Z, Liu S, Xu J, Zhang X, Han D, Liu J, et al. Adult Connective Tissue-Resident Mast Cells Originate from Late Erythro-Myeloid Progenitors. Immunity. 2018;49:640-653.e5 pubmed 出版商
Liakopoulos V, Jeron A, Shah A, Bruder D, Mertens P, Gorny X. Hemodialysis-related changes in phenotypical features of monocytes. Sci Rep. 2018;8:13964 pubmed 出版商
Sabbagh M, Heng J, Luo C, Castanon R, Nery J, Rattner A, et al. Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells. elife. 2018;7: pubmed 出版商
Sokol C, Camire R, Jones M, Luster A. The Chemokine Receptor CCR8 Promotes the Migration of Dendritic Cells into the Lymph Node Parenchyma to Initiate the Allergic Immune Response. Immunity. 2018;49:449-463.e6 pubmed 出版商
Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, et al. TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. Cell. 2018;174:1477-1491.e19 pubmed 出版商
Cong J, Wang X, Zheng X, Wang D, Fu B, Sun R, et al. Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression. Cell Metab. 2018;28:243-255.e5 pubmed 出版商
Zukauskas A, Mrsny R, Cortés Barrantes P, Turner J, Leong J, McCormick B. Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection. mSphere. 2018;3: pubmed 出版商
Geng X, Wang X, Luo M, Xing M, Wu Y, Li W, et al. Induction of neutrophil apoptosis by a Bcl-2 inhibitor reduces particulate matter-induced lung inflammation. Aging (Albany NY). 2018;10:1415-1423 pubmed 出版商
Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, et al. Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Science. 2018;360: pubmed 出版商
Skucha A, Ebner J, Schmöllerl J, Roth M, Eder T, César Razquin A, et al. MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity. Nat Commun. 2018;9:1983 pubmed 出版商
Laban H, Weigert A, Zink J, Elgheznawy A, Schürmann C, Günther L, et al. VASP regulates leukocyte infiltration, polarization, and vascular repair after ischemia. J Cell Biol. 2018;217:1503-1519 pubmed 出版商
Kakizaki M, Watanabe R. IL-10 expression in pyramidal neurons after neuropathogenic coronaviral infection. Neuropathology. 2017;37:398-406 pubmed 出版商
Yin Z, Raj D, Saiepour N, Van Dam D, Brouwer N, Holtman I, et al. Immune hyperreactivity of A? plaque-associated microglia in Alzheimer's disease. Neurobiol Aging. 2017;55:115-122 pubmed 出版商
Harvey R, Howard V, Lemus M, Jois T, Andrews Z, Sleeman M. The Ghrelin/GOAT System Regulates Obesity-Induced Inflammation in Male Mice. Endocrinology. 2017;158:2179-2189 pubmed 出版商
Currier M, Sprague L, Rizvi T, Nartker B, Chen C, Wang P, et al. Aurora A kinase inhibition enhances oncolytic herpes virotherapy through cytotoxic synergy and innate cellular immune modulation. Oncotarget. 2017;8:17412-17427 pubmed 出版商
Moderzynski K, Papp S, Rauch J, Heine L, Kuehl S, Richardt U, et al. CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity. PLoS Negl Trop Dis. 2016;10:e0005089 pubmed 出版商
Reinert L, Lopušná K, Winther H, Sun C, Thomsen M, Nandakumar R, et al. Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS. Nat Commun. 2016;7:13348 pubmed 出版商
Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed 出版商
Bennett M, Bennett F, Liddelow S, Ajami B, Zamanian J, Fernhoff N, et al. New tools for studying microglia in the mouse and human CNS. Proc Natl Acad Sci U S A. 2016;113:E1738-46 pubmed 出版商
Kim I, Mlsna L, Yoon S, Le B, Yu S, Xu D, et al. A postnatal peak in microglial development in the mouse hippocampus is correlated with heightened sensitivity to seizure triggers. Brain Behav. 2015;5:e00403 pubmed 出版商
Ioannidis L, Nie C, Ly A, Ryg Cornejo V, Chiu C, Hansen D. Monocyte- and Neutrophil-Derived CXCL10 Impairs Efficient Control of Blood-Stage Malaria Infection and Promotes Severe Disease. J Immunol. 2016;196:1227-38 pubmed 出版商
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Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed 出版商
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产品信息
抗原 :
CD11b
Apps. Abbrev. :
流式细胞仪
目录 :
101235
克隆 :
M1/70
产品 :
亮紫色421™抗小鼠/人类CD11b
抗体亚型 :
Rat IgG2b, κ
其他名称 :
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
规格 :
125微升
价格(美元) :
165美元
反应物种 :
Mouse, Human, Cynomolgus, Rhesus
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
BV421
免疫原 :
C57BL/10 splenocytes
应用注释 :
Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F). Additional reported applications (for relevant formats of this clone) include: immunoprecipitation 1,4 , in vitro blocking 3,9,12 , depletion 2,8 , immunofluorescence microscopy 6,7,10 , immunohistochemistry of acetone-fixed frozen sections 5,11-13 , and spatial biology (IBEX) 35,36 . For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) (Cat. No. 101248).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。