产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化抗小鼠CD40
目录 :
102802
规格 :
500微克
价格 :
235美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
1C10
反应物种 :
小鼠
应用 :
中和反应, 免疫沉淀, 流式细胞仪
更多信息或购买 :
BioLegend 产品网页
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 1a
Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6c
Khameneh H, Ho A, Spreafico R, Derks H, Quek H, Mortellaro A. The Syk-NFAT-IL-2 Pathway in Dendritic Cells Is Required for Optimal Sterile Immunity Elicited by Alum Adjuvants. J Immunol. 2017;198:196-204 pubmed
  • 流式细胞仪; 小鼠; 图 s4e
Klotz L, Kuzmanov I, Hucke S, Gross C, Posevitz V, Dreykluft A, et al. B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity. Proc Natl Acad Sci U S A. 2016;113:E6182-E6191 pubmed
  • 流式细胞仪; 小鼠; 图 3
LUCAS B, White A, Ulvmar M, Nibbs R, Sitnik K, Agace W, et al. CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice. Eur J Immunol. 2015;45:574-83 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
McDonnell A, Lesterhuis W, Khong A, Nowak A, Lake R, Currie A, et al. Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy. Eur J Immunol. 2015;45:49-59 pubmed 出版商
Sakaguchi T, Okumura R, Ono C, Okuzaki D, Kawai T, Okochi Y, et al. TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes. Cell Rep. 2020;31:107755 pubmed 出版商
Lu X, Chu C, Fang T, Rayon Estrada V, Fang F, Patke A, et al. MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition. Cell Rep. 2019;28:472-485.e5 pubmed 出版商
Obieglo K, Costain A, Webb L, Ozir Fazalalikhan A, Brown S, MacDonald A, et al. Type I interferons provide additive signals for murine regulatory B cell induction by Schistosoma mansoni eggs. Eur J Immunol. 2019;49:1226-1234 pubmed 出版商
Graf R, Li X, Chu V, Rajewsky K. sgRNA Sequence Motifs Blocking Efficient CRISPR/Cas9-Mediated Gene Editing. Cell Rep. 2019;26:1098-1103.e3 pubmed 出版商
Hoves S, Ooi C, Wolter C, Sade H, Bissinger S, Schmittnaegel M, et al. Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity. J Exp Med. 2018;215:859-876 pubmed 出版商
Le Q, Maizels N. Cell Cycle Regulates Nuclear Stability of AID and Determines the Cellular Response to AID. PLoS Genet. 2015;11:e1005411 pubmed 出版商
Rastelli J, Hömig Hölzel C, Seagal J, Muller W, Hermann A, Rajewsky K, et al. LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1. Blood. 2008;111:1448-55 pubmed
Zhang P, Sun D, Ke Y, Kaplan H, Shao H. The net effect of costimulatory blockers is dependent on the subset and activation status of the autoreactive T cells. J Immunol. 2007;178:474-9 pubmed
Ashman R, Goeken J, Drahos J, Lenert P. Sequence requirements for oligodeoxyribonucleotide inhibitory activity. Int Immunol. 2005;17:411-20 pubmed
产品信息
抗原 :
CD40
Apps. Abbrev. :
Flow Cytometry, Costim, Block, IP
目录 :
102802
克隆 :
1C10
产品 :
纯化抗小鼠CD40
抗体亚型 :
Rat IgG2a, κ
其他名称 :
Bp50, TNFRSF5
规格 :
500微克
价格(美元) :
235美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PURE
应用注释 :
The 1C10 antibody has been reported to stimulate B cell proliferation and block CD40-CD40L interactions. Additional reported applications (for the relevant formats) include: immunoprecipitation, blocking 5,6 of CD40 ligand binding, and in vitro stimulation of B cell proliferation 1-3 . The LEAF™ purified antibody (Endotoxin 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 102810). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 102812) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin 0.01 EU/µg).
更多信息或购买 :
BioLegend 产品网页
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品，旨在加速生命科学领域的研发工作。